Positions
- Postdoctoral Associate
-
Department of Neuroscience
Baylor College of Medicine
Houston, TX US
Education
- Internship at Tulane University
- New Orleans, Louisiana United States
- Neuroscience, Mentor: Dr. Jeffrey Tasker
- PhD from Louisiana Tech University
- Ruston, Louisiana United States
- Biomedical Engineering, Mentor: Dr. Alan Chiu
- Postdoctoral Fellowship at University of Michigan
- Ann Arbor, Michigan United States
- Neurology, Mentor: Dr. William Stacey
- Postdoctoral Fellowship at Baylor College of Medicine
- Houston, Texas United States
- Neuroscience, Mentor: Dr. Mingshan Xue
Honors & Awards
- Dean’s Award for Excellence
- Baylor College of Medicine
- Young Investigator Award
- American Epilepsy Society
Professional Interests
- Neurology - Epilepsy
- Neural Signal Processing
- Gene Therapy
Selected Publications
- Chen W, Cai ZL, Chao ES, Chen H, Longley CM, Hao S, Chao HT, Kim JH, Messier JE, Zoghbi HY, Tang J, Swann JW, Xue M "Stxbp1/Munc18-1 haploinsufficiency impairs inhibition and mediates key neurological features of STXBP1 encephalopathy." Elife. 2020 February 19; 9 : e48705. Pubmed PMID: 32073399
- Yin J, Chen W, Chao ES, Soriano S, Wang L, Wang W, Cummock SE, Tao H, Pang K, Liu Z, Pereira FA, Samaco RC, Zoghbi HY, Xue M, Schaaf CP "Otud7a Knockout Mice Recapitulate Many Neurological Features of 15q13.3 Microdeletion Syndrome." Am J Hum Genet. 2018 February 1; 102 (2): 296-308. Pubmed PMID: 29395075
- Yin J, Chen W, Yang H, Xue M, Schaaf CP "Chrna7 deficient mice manifest no consistent neuropsychiatric and behavioral phenotypes." Sci Rep. 2017 January 3; 7 : 39941. Pubmed PMID: 28045139
- Luna-Munguia H, Starski P, Chen W, Gliske S, Stacey WC "Control of in vivo ictogenesis via endogenous synaptic pathways." Sci Rep. 2017 May 2; 7 (1): 1311. Pubmed PMID: 28465556
- Ure K, Lu H, Wang W, Ito-Ishida A1,2, Wu Z2,4, He LJ, Sztainberg Y, Chen W, Tang J, Zoghbi HY "Restoration of Mecp2 expression in GABAergic neurons is sufficient to rescue multiple disease features in a mouse model of Rett syndrome." Elife. 2016 June 21; 5 : e14198. Pubmed PMID: 27328321
- Meng X, Wang W, Lu H, He LJ, Chen W, Chao ES, Fiorotto ML, Tang B, Herrera JA, Seymour ML, Neul JL, Pereira FA, Tang J, Xue M, Zoghbi HY "Manipulations of MeCP2 in glutamatergic neurons highlight their contributions to Rett and other neurological disorders." Elife. 2016 June 21; 5 : e14199. Pubmed PMID: 27328325
- Chen W, Cahoy DO, Tasker JG, Chiu AW "Kernel duration and modulation gain in coupled oscillator model and their implications on the progression of seizures." Network. 2012 May 9; 23 (1-2): 59-75. Pubmed PMID: 22571251
Projects
- Transgenic Mouse Models of STXBP1-Related Pediatric Epileptic Encephalopathies
- Baylor College of Medicine
Funding
- 2009 Summer research mentoring program National Institutes of Health
- Postdoctoral Research Fellowship American Epilepsy Society
- 2020 NRI Zoghbi Scholar Award Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital
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