Teresa
Middle Name
A
Davis, Ph.D.
Middle Name
A
Picture
Positions
- Professor
-
Pediatrics-Nutrition
Baylor College of Medicine
Houston, TX US
- Adjunct Professor
-
Department of Nutrition and Food Science; Department of Animal Science
Texas A&M
United States
Education
- Advanced Training from Washington University
- 01/1980 - St. Louis, MO United States
- Ph.D. from University Of Tennessee
- 01/1980 - Knoxville, TN United States
- M.S. from University Of Tennessee
- 01/1976 - Knoxville, TN United States
- B.S. from University Of Tennessee
- 01/1975 - Knoxville, TN United States
Honors & Awards
- Editor-in-Chief
- The Journal of Nutrition (01/2014 - 12/2023)
- Past President
- American Society for Nutrition (06/2013 - 01/2014)
- Director-at-Large
- American Society of Animal Science (07/2014 - 07/2017)
- Scientific Advisor
- International Life Sciences Institute North America Food, Nutrition & Safety Program (01/2016 - 01/2019)
- Research Mentor Award
- Department of Pediatrics, Baylor College of Medicine (06/2010)
- Animal Growth and Development Award
- American Society of Animal Science (07/2007)
- Fulbright United States Distinguished American Scholar
- Fulbright New Zealand-United States Educational Foundation (01/2001)
- E.L.R. Stokstad Award
- American Society for Nutrition (04/1998)
- Morrison Award
- American Society of Animal Science (07/2020)
- Fellow
- American Society of Animal Science (07/2020)
- 2020 Dietary Guidelines Advisory Committee Member
- USDA/HHS (01/2019 - 07/2020)
- Distinguished Foreign Scholar
- China Foreign Expert Administration (01/2012)
Websites
Selected Publications
- Suryawan A, Fiorotto ML, and Davis TA "Differential regulation of mTORC1 activation by leucine and β-hydroxy-β-methylbutyrate in skeletal muscle of neonatal pigs.." J Appl Physiol. 2020 (128): 286-295. Pubmed PMID: 31944890
- El-Kadi SW, Boutry C, Suryawan A, Gazzaneo MC, Orellana RA, Srivastava N, Nguyen HV, Kimball SR, Fiorotto ML, and Davis TA "Long-term intermittent bolus feeding enhances lean growth more than continuous feeding by stimulating mTORC1-dependent translation initiation in neonatal pigs.." Am J Clin Nutr. 2018 108 : 830-841. Pubmed PMID: 30239549
- Naberhuis JK, Suryawan A, Nguyen HV, Hernandez-Garcia A, Cruz SM, Lau PE, Olutoye OO, Stoll B, Burrin DG, Fiorotto ML, and Davis TA. "Prematurity blunts the feeding-induced stimulation of translation initiation signaling and protein synthesis in muscle of neonatal piglets.." Am J Physiol Endocrinol Metab. 2019 (317): E839-E851. Pubmed PMID: 31503514
- Rudar M, Fiorotto ML, and Davis TA "Regulation of muscle growth in early postnatal life in a swine model.." Ann Rev Animal Biosci. 2019 7 : 309-335. Pubmed PMID: 30388025
- Davis TA, Fiorotto ML, Burrin DG, Vann RC, Reeds PJ, Nguyen HV, Beckett PR, Bush JA "Acute IGF-I infusion stimulates protein synthesis in skeletal muscle and other tissues of neonatal pigs.." Am. J. Physiol. Endocrinol. Metab.. 2002 October ; 283 (4): E638-47. Pubmed PMID: 12217880
- Escobar J, Frank JW, Suryawan A, Nguyen HV, Davis TA "Amino acid availability and age affect the leucine stimulation of protein synthesis and eIF4F formation in muscle.." Am. J. Physiol. Endocrinol. Metab.. 2007 December ; 293 (6): E1615-21. Pubmed PMID: 17878223
- Davis TA, Nguyen HV, Garcia-Bravo R, Fiorotto ML, Jackson EM, Lewis DS, Lee DR, Reeds PJ "Amino acid composition of human milk is not unique.." J. Nutr.. 1994 July ; 124 (7): 1126-32. Pubmed PMID: 8027865
- Davis TA, Nguyen HV, Costa DP, Reeds PJ "Amino acid composition of pinniped milk.." Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 1995 March ; 110 (3): 633-9. Pubmed PMID: 7584837
- Davis TA, Nguyen HV, Garcia-Bravo R, Fiorotto ML, Jackson EM, Reeds PJ "Amino acid composition of the milk of some mammalian species changes with stage of lactation.." Br. J. Nutr.. 1994 December ; 72 (6): 845-53. Pubmed PMID: 7827005
- Davis TA, Fiorotto ML, Reeds PJ "Amino acid compositions of body and milk protein change during the suckling period in rats.." J. Nutr.. 1993 May ; 123 (5): 947-56. Pubmed PMID: 8487106
- Reeds PJ, Burrin DG, Davis TA, Stoll B "Amino acid metabolism and the energetics of growth.." Arch Tierernahr. 1998 51 (41308): 187-97. Pubmed PMID: 9672716
- Orellana RA, Jeyapalan A, Escobar J, Frank JW, Nguyen HV, Suryawan A, Davis TA "Amino acids augment muscle protein synthesis in neonatal pigs during acute endotoxemia by stimulating mTOR-dependent translation initiation.." Am. J. Physiol. Endocrinol. Metab.. 2007 November ; 293 (5): E1416-25. Pubmed PMID: 17848637
- Suryawan A, O'Connor PM, Kimball SR, Bush JA, Nguyen HV, Jefferson LS, Davis TA "Amino acids do not alter the insulin-induced activation of the insulin signaling pathway in neonatal pigs.." J. Nutr.. 2004 January ; 134 (1): 24-30. Pubmed PMID: 14704288
- Davis TA, Fiorotto ML, Nguyen HV, Burrin DG "Aminoacyl-tRNA and tissue free amino acid pools are equilibrated after a flooding dose of phenylalanine.." Am. J. Physiol.. 1999 July ; 277 (1): E103-9. Pubmed PMID: 10409133
- El-Kadi SW, Suryawan A, Gazzaneo MC, Srivastava N, Orellana RA, Nguyen HV, Lobley GE, Davis TA "Anabolic signaling and protein deposition are enhanced by intermittent compared with continuous feeding in skeletal muscle of neonates.." Am. J. Physiol. Endocrinol. Metab.. 2012 March ; 302 (6): E674-86. Pubmed PMID: 22215651
- Wu G, Bazer FW, Davis TA, Kim SW, Li P, Marc Rhoads J, Carey Satterfield M, Smith SB, Spencer TE, Yin Y "Arginine metabolism and nutrition in growth, health and disease.." Amino Acids. 2009 May ; 37 (1): 153-68. Pubmed PMID: 19030957
- Fiorotto ML, Davis TA, Schoknecht P, Mersmann HJ, Pond WG "Both maternal over- and undernutrition during gestation increase the adiposity of young adult progeny in rats.." Obes. Res.. 1995 March ; 3 (2): 131-41. Pubmed PMID: 7719959
- Stoll B, Horst DA, Cui L, Chang X, Ellis KJ, Hadsell DL, Suryawan A, Kurundkar A, Maheshwari A, Davis TA, Burrin DG "Chronic parenteral nutrition induces hepatic inflammation, steatosis, and insulin resistance in neonatal pigs.." J. Nutr.. 2010 December ; 140 (12): 2193-200. Pubmed PMID: 20980637
- Burrin DG, Davis TA, Ebner S, Schoknecht PA, Fiorotto ML, Reeds PJ "Colostrum enhances the nutritional stimulation of vital organ protein synthesis in neonatal pigs.." J. Nutr.. 1997 July ; 127 (7): 1284-9. Pubmed PMID: 9202081
- Reynolds LP, Ireland JJ, Caton JS, Bauman DE, Davis TA "Commentary on domestic animals in agricultural and biomedical research: an endangered enterprise.." J. Nutr.. 2009 March ; 139 (3): 427-8. Pubmed PMID: 19158219
- Beckett PR, Fiorotto ML, Davis TA, Reeds PJ "Corticosterone has independent effects on tissue maturation and growth in the suckling rat.." Pediatr. Res.. 1996 March ; 39 (3): 395-400. Pubmed PMID: 8929857
- Orellana RA, Suryawan A, Wilson FA, Gazzaneo MC, Fiorotto ML, Nguyen HV, Davis TA "Development aggravates the severity of skeletal muscle catabolism induced by endotoxemia in neonatal pigs.." Am. J. Physiol. Regul. Integr. Comp. Physiol.. 2012 March ; 302 (6): R682-90. Pubmed PMID: 22277935
- Suryawan A, Nguyen HV, Bush JA, Davis TA "Developmental changes in the feeding-induced activation of the insulin-signaling pathway in neonatal pigs.." Am. J. Physiol. Endocrinol. Metab.. 2001 November ; 281 (5): E908-15. Pubmed PMID: 11595645
- Davis TA, Nguyen HV, Suryawan A, Bush JA, Jefferson LS, Kimball SR "Developmental changes in the feeding-induced stimulation of translation initiation in muscle of neonatal pigs.." Am. J. Physiol. Endocrinol. Metab.. 2000 December ; 279 (6): E1226-34. Pubmed PMID: 11093908
- Kimball SR, Farrell PA, Nguyen HV, Jefferson LS, Davis TA "Developmental decline in components of signal transduction pathways regulating protein synthesis in pig muscle.." Am. J. Physiol. Endocrinol. Metab.. 2002 March ; 282 (3): E585-92. Pubmed PMID: 11832361
- Suryawan A, Davis TA "Developmental regulation of protein kinase B activation is isoform specific in skeletal muscle of neonatal pigs.." Pediatr. Res.. 2005 October ; 58 (4): 719-24. Pubmed PMID: 16189199
- Suryawan A, Escobar J, Frank JW, Nguyen HV, Davis TA "Developmental regulation of the activation of signaling components leading to translation initiation in skeletal muscle of neonatal pigs.." Am. J. Physiol. Endocrinol. Metab.. 2006 October ; 291 (4): E849-59. Pubmed PMID: 16757550
- Burrin DG, Wester TJ, Davis TA, Fiorotto ML, Chang X "Dexamethasone inhibits small intestinal growth via increased protein catabolism in neonatal pigs.." Am. J. Physiol.. 1999 February ; 276 (2): E269-77. Pubmed PMID: 9950786
- Frank JW, Escobar J, Suryawan A, Nguyen HV, Kimball SR, Jefferson LS, Davis TA "Dietary protein and lactose increase translation initiation factor activation and tissue protein synthesis in neonatal pigs.." Am. J. Physiol. Endocrinol. Metab.. 2006 February ; 290 (2): E225-33. Pubmed PMID: 16144813
- Davis TA, Fiorotto ML, Beckett PR, Burrin DG, Reeds PJ, Wray-Cahen D, Nguyen HV "Differential effects of insulin on peripheral and visceral tissue protein synthesis in neonatal pigs.." Am. J. Physiol. Endocrinol. Metab.. 2001 May ; 280 (5): E770-9. Pubmed PMID: 11287360
- Gazzaneo MC, Orellana RA, Suryawan A, Tuckow AP, Kimball SR, Wilson FA, Nguyen HV, Torrazza RM, Fiorotto ML, Davis TA "Differential Regulation of Protein Synthesis and mTOR Signaling in Skeletal Muscle and Visceral Tissues of Neonatal Pigs After a Meal.." Pediatr. Res.. 2011 September ; 70 (3): 253-60. Pubmed PMID: 21654549
- Suryawan A, O'Connor PM, Bush JA, Nguyen HV, Davis TA "Differential regulation of protein synthesis by amino acids and insulin in peripheral and visceral tissues of neonatal pigs.." Amino Acids. 2009 May ; 37 (1): 97-104. Pubmed PMID: 18683020
- Orellana RA, O'Connor PM, Nguyen HV, Bush JA, Suryawan A, Thivierge MC, Fiorotto ML, Davis TA "Endotoxemia reduces skeletal muscle protein synthesis in neonates.." Am. J. Physiol. Endocrinol. Metab.. 2002 November ; 283 (5): E909-16. Pubmed PMID: 12376317
- Kimball SR, Orellana RA, O'Connor PM, Suryawan A, Bush JA, Nguyen HV, Thivierge MC, Jefferson LS, Davis TA "Endotoxin induces differential regulation of mTOR-dependent signaling in skeletal muscle and liver of neonatal pigs.." Am. J. Physiol. Endocrinol. Metab.. 2003 September ; 285 (3): E637-44. Pubmed PMID: 12773308
- Davis TA, Fiorotto ML, Nguyen HV, Reeds PJ "Enhanced response of muscle protein synthesis and plasma insulin to food intake in suckled rats.." Am. J. Physiol.. 1993 August ; 265 (2): R334-40. Pubmed PMID: 8368387
- Suryawan A, Torrazza RM, Gazzaneo MC, Orellana RA, Fiorotto ML, El-Kadi SW, Srivastava N, Nguyen HV, Davis TA "Enteral leucine supplementation increases protein synthesis in skeletal and cardiac muscles and visceral tissues of neonatal pigs through mTORC1-dependent pathways.." Pediatr. Res.. 2012 April ; 71 (4): 324-31. Pubmed PMID: 22391631
- Wester TJ, Davis TA, Fiorotto ML, Burrin DG "Exogenous growth hormone stimulates somatotropic axis function and growth in neonatal pigs.." Am. J. Physiol.. 1998 January ; 274 (1): E29-37. Pubmed PMID: 9458744
- Schoknecht PA, Ebner S, Skottner A, Burrin DG, Davis TA, Ellis K, Pond WG "Exogenous insulin-like growth factor-I increases weight gain in intrauterine growth-retarded neonatal pigs.." Pediatr. Res.. 1997 August ; 42 (2): 201-7. Pubmed PMID: 9262223
- Suryawan A, Frank JW, Nguyen HV, Davis TA "Expression of the TGF-beta family of ligands is developmentally regulated in skeletal muscle of neonatal rats.." Pediatr. Res.. 2006 February ; 59 (2): 175-9. Pubmed PMID: 16439574
- Wilson FA, Suryawan A, Orellana RA, Nguyen HV, Jeyapalan AS, Gazzaneo MC, Davis TA "Fed levels of amino acids are required for the somatotropin-induced increase in muscle protein synthesis.." Am. J. Physiol. Endocrinol. Metab.. 2008 October ; 295 (4): E876-83. Pubmed PMID: 18682537
- Wilson FA, Suryawan A, Orellana RA, Kimball SR, Gazzaneo MC, Nguyen HV, Fiorotto ML, Davis TA "Feeding rapidly stimulates protein synthesis in skeletal muscle of neonatal pigs by enhancing translation initiation.." J. Nutr.. 2009 October ; 139 (10): 1873-80. Pubmed PMID: 19692527
- Jeyapalan AS, Orellana RA, Suryawan A, O'Connor PM, Nguyen HV, Escobar J, Frank JW, Davis TA "Glucose stimulates protein synthesis in skeletal muscle of neonatal pigs through an AMPK- and mTOR-independent process.." Am. J. Physiol. Endocrinol. Metab.. 2007 August ; 293 (2): E595-603. Pubmed PMID: 17551002
- Burrin DG, Davis TA, Fiorotto ML, Reeds PJ "Hepatic protein synthesis in suckling rats: effects of stage of development and fasting.." Pediatr. Res.. 1992 March ; 31 (3): 247-52. Pubmed PMID: 1373233
- Fiorotto ML, Sosa HA, Davis TA "In vivo measurement of muscle protein synthesis rate using the flooding dose technique.." Methods Mol. Biol.. 2012 798 : 245-64. Pubmed PMID: 22130841
- O'Connor PM, Bush JA, Suryawan A, Nguyen HV, Davis TA "Insulin and amino acids independently stimulate skeletal muscle protein synthesis in neonatal pigs.." Am. J. Physiol. Endocrinol. Metab.. 2003 January ; 284 (1): E110-9. Pubmed PMID: 12388131
- Orellana RA, Suryawan A, Kimball SR, Wu G, Nguyen HV, Jefferson LS, Davis TA "Insulin signaling in skeletal muscle and liver of neonatal pigs during endotoxemia.." Pediatr. Res.. 2008 November ; 64 (5): 505-10. Pubmed PMID: 18596577
- Orellana RA, Kimball SR, Suryawan A, Escobar J, Nguyen HV, Jefferson LS, Davis TA "Insulin stimulates muscle protein synthesis in neonates during endotoxemia despite repression of translation initiation.." Am. J. Physiol. Endocrinol. Metab.. 2007 February ; 292 (2): E629-36. Pubmed PMID: 17047163
- Suryawan A, Nguyen HV, Orellana RA, Bush JA, Davis TA "Insulin/insulin-like growth factor-I hybrid receptor abundance decreases with development in suckling pigs.." J. Nutr.. 2003 September ; 133 (9): 2783-7. Pubmed PMID: 12949365
- Gazzaneo MC, Suryawan A, Orellana RA, Torrazza RM, El-Kadi SW, Wilson FA, Kimball SR, Srivastava N, Nguyen HV, Fiorotto ML, Davis TA "Intermittent bolus feeding has a greater stimulatory effect on protein synthesis in skeletal muscle than continuous feeding in neonatal pigs.." J. Nutr.. 2011 December ; 141 (12): 2152-8. Pubmed PMID: 22013195
- Escobar J, Frank JW, Suryawan A, Nguyen HV, Van Horn CG, Hutson SM, Davis TA "Leucine and {alpha}-Ketoisocaproic Acid, but Not Norleucine, Stimulate Skeletal Muscle Protein Synthesis in Neonatal Pigs.." J. Nutr.. 2010 August ; 140 (8): 1418-24. Pubmed PMID: 20534881
- Motil KJ, Opekun AR, Montandon CM, Berthold HK, Davis TA, Klein PD, Reeds PJ "Leucine oxidation changes rapidly after dietary protein intake is altered in adult women but lysine flux is unchanged as is lysine incorporation into VLDL-apolipoprotein B-100.." J. Nutr.. 1994 January ; 124 (1): 41-51. Pubmed PMID: 8283293
- Suryawan A, Jeyapalan AS, Orellana RA, Wilson FA, Nguyen HV, Davis TA "Leucine stimulates protein synthesis in skeletal muscle of neonatal pigs by enhancing mTORC1 activation.." Am. J. Physiol. Endocrinol. Metab.. 2008 October ; 295 (4): E868-75. Pubmed PMID: 18682538
- Murgas Torrazza R, Suryawan A, Gazzaneo MC, Orellana RA, Frank JW, Nguyen HV, Fiorotto ML, El-Kadi S, Davis TA "Leucine supplementation of a low-protein meal increases skeletal muscle and visceral tissue protein synthesis in neonatal pigs by stimulating mTOR-dependent translation initiation.." J. Nutr.. 2010 December ; 140 (12): 2145-52. Pubmed PMID: 20962152
- Bergeron K, Julien P, Davis TA, Myre A, Thivierge MC "Long-chain n-3 fatty acids enhance neonatal insulin-regulated protein metabolism in piglets by differentially altering muscle lipid composition.." J. Lipid Res.. 2007 November ; 48 (11): 2396-410. Pubmed PMID: 17673528
- Gingras AA, White PJ, Chouinard PY, Julien P, Davis TA, Dombrowski L, Couture Y, Dubreuil P, Myre A, Bergeron K, Marette A, Thivierge MC "Long-chain omega-3 fatty acids regulate bovine whole-body protein metabolism by promoting muscle insulin signalling to the Akt-mTOR-S6K1 pathway and insulin sensitivity.." J. Physiol. (Lond.). 2007 February 15; 579 : 269-84. Pubmed PMID: 17158167
- Orellana RA, O'Connor PM, Bush JA, Suryawan A, Thivierge MC, Nguyen HV, Fiorotto ML, Davis TA "Modulation of muscle protein synthesis by insulin is maintained during neonatal endotoxemia.." Am. J. Physiol. Endocrinol. Metab.. 2006 July ; 291 (1): E159-66. Pubmed PMID: 16478773
- Fiorotto ML, Davis TA, Reeds PJ, Burrin DG "Nonnutritive factors in colostrum enhance myofibrillar protein synthesis in the newborn Pig.." Pediatr. Res.. 2000 October ; 48 (4): 511-7. Pubmed PMID: 11004243
- Burrin DG, Davis TA, Ebner S, Schoknecht PA, Fiorotto ML, Reeds PJ, McAvoy S "Nutrient-independent and nutrient-dependent factors stimulate protein synthesis in colostrum-fed newborn pigs.." Pediatr. Res.. 1995 May ; 37 (5): 593-9. Pubmed PMID: 7603776
- Davis TA, Reeds PJ "Of flux and flooding: the advantages and problems of different isotopic methods for quantifying protein turnover in vivo : II. Methods based on the incorporation of a tracer.." Curr Opin Clin Nutr Metab Care. 2001 January ; 4 (1): 51-6. Pubmed PMID: 11122560
- Reeds PJ, Davis TA "Of flux and flooding: the advantages and problems of different isotopic methods for quantifying protein turnover in vivo: I. Methods based on the dilution of a tracer.." Curr Opin Clin Nutr Metab Care. 1999 January ; 2 (1): 23-8. Pubmed PMID: 10453326
- Frank JW, Escobar J, Nguyen HV, Jobgen SC, Jobgen WS, Davis TA, Wu G "Oral N-carbamylglutamate supplementation increases protein synthesis in skeletal muscle of piglets.." J. Nutr.. 2007 February ; 137 (2): 315-9. Pubmed PMID: 17237304
- Davis TA, Burrin DG, Fiorotto ML "Peter J. Reeds (February 22, 1945-August 13, 2002).." J. Nutr.. 2003 January ; 133 (1): 41402. Pubmed PMID: 12514258
- Escobar J, Frank JW, Suryawan A, Nguyen HV, Kimball SR, Jefferson LS, Davis TA "Physiological rise in plasma leucine stimulates muscle protein synthesis in neonatal pigs by enhancing translation initiation factor activation.." Am. J. Physiol. Endocrinol. Metab.. 2005 May ; 288 (5): E914-21. Pubmed PMID: 15644455
- Burrin DG, Shulman RJ, Reeds PJ, Davis TA, Gravitt KR "Porcine colostrum and milk stimulate visceral organ and skeletal muscle protein synthesis in neonatal piglets.." J. Nutr.. 1992 June ; 122 (6): 1205-13. Pubmed PMID: 1375287
- Thivierge MC, Bush JA, Suryawan A, Nguyen HV, Orellana RA, Burrin DG, Jahoor F, Davis TA "Positive net movements of amino acids in the hindlimb after overnight food deprivation contribute to sustaining the elevated anabolism of neonatal pigs.." J. Appl. Physiol.. 2008 105 (6): 1959-66. Pubmed PMID: 18801965
- Davis TA, Suryawan A, Orellana RA, Nguyen HV, Fiorotto ML "Postnatal ontogeny of skeletal muscle protein synthesis in pigs.." J. Anim. Sci.. 2008 April ; 86 (14): E13-8. Pubmed PMID: 17785597
- Reeds PJ, Burrin DG, Davis TA, Fiorotto ML, Stoll B, van Goudoever JB "Protein nutrition of the neonate.." Proc Nutr Soc. 2000 February ; 59 (1): 87-97. Pubmed PMID: 10828178
- Frank JW, Escobar J, Suryawan A, Kimball SR, Nguyen HV, Jefferson LS, Davis TA "Protein synthesis and translation initiation factor activation in neonatal pigs fed increasing levels of dietary protein.." J. Nutr.. 2005 June ; 135 (6): 1374-81. Pubmed PMID: 15930440
- Davis TA, Fiorotto ML, Nguyen HV, Reeds PJ "Protein turnover in skeletal muscle of suckling rats.." Am. J. Physiol.. 1989 November ; 257 (5): R1141-6. Pubmed PMID: 2480066
- Suryawan A, Davis TA "Protein-tyrosine-phosphatase 1B activation is regulated developmentally in muscle of neonatal pigs.." Am. J. Physiol. Endocrinol. Metab.. 2003 January ; 284 (1): E47-54. Pubmed PMID: 12388170
- Burrin DG, Davis TA "Proteins and amino acids in enteral nutrition.." Curr Opin Clin Nutr Metab Care. 2004 January ; 7 (1): 79-87. Pubmed PMID: 15090907
- Escobar J, Frank JW, Suryawan A, Nguyen HV, Kimball SR, Jefferson LS, Davis TA "Regulation of cardiac and skeletal muscle protein synthesis by individual branched-chain amino acids in neonatal pigs.." Am. J. Physiol. Endocrinol. Metab.. 2006 April ; 290 (4): E612-21. Pubmed PMID: 16278252
- Davis TA, Fiorotto ML "Regulation of muscle growth in neonates.." Curr Opin Clin Nutr Metab Care. 2009 January ; 12 (1): 78-85. Pubmed PMID: 19057192
- Orellana RA, Kimball SR, Nguyen HV, Bush JA, Suryawan A, Thivierge MC, Jefferson LS, Davis TA "Regulation of muscle protein synthesis in neonatal pigs during prolonged endotoxemia.." Pediatr. Res.. 2004 March ; 55 (3): 442-9. Pubmed PMID: 14681494
- Fiorotto ML, Davis TA, Reeds PJ "Regulation of myofibrillar protein turnover during maturation in normal and undernourished rat pups.." Am. J. Physiol. Regul. Integr. Comp. Physiol.. 2000 April ; 278 (4): R845-54. Pubmed PMID: 10749771
- O'Connor PM, Kimball SR, Suryawan A, Bush JA, Nguyen HV, Jefferson LS, Davis TA "Regulation of neonatal liver protein synthesis by insulin and amino acids in pigs.." Am. J. Physiol. Endocrinol. Metab.. 2004 June ; 286 (6): E994-E1003. Pubmed PMID: 14761876
- Suryawan A, Davis TA "Regulation of protein synthesis by amino acids in muscle of neonates.." Front. Biosci.. 2011 16 : 1445-60. Pubmed PMID: 21196241
- O'Connor PM, Kimball SR, Suryawan A, Bush JA, Nguyen HV, Jefferson LS, Davis TA "Regulation of translation initiation by insulin and amino acids in skeletal muscle of neonatal pigs.." Am. J. Physiol. Endocrinol. Metab.. 2003 July ; 285 (1): E40-53. Pubmed PMID: 12637260
- Davis TA, Fiorotto ML, Nguyen HV, Burrin DG, Reeds PJ "Response of muscle protein synthesis to fasting in suckling and weaned rats.." Am. J. Physiol.. 1991 December ; 261 (6): R1373-80. Pubmed PMID: 1721504
- Wray-Cahen D, Nguyen HV, Burrin DG, Beckett PR, Fiorotto ML, Reeds PJ, Wester TJ, Davis TA "Response of skeletal muscle protein synthesis to insulin in suckling pigs decreases with development.." Am. J. Physiol.. 1998 October ; 275 (4): E602-9. Pubmed PMID: 9755078
- Burrin DG, Davis TA, Fiorotto ML, Reeds PJ "Role of milk-borne vs endogenous insulin-like growth factor I in neonatal growth.." J. Anim. Sci.. 1997 October ; 75 (10): 2739-43. Pubmed PMID: 9331878
- Davis TA, Burrin DG, Fiorotto ML, Reeds PJ, Jahoor F "Roles of insulin and amino acids in the regulation of protein synthesis in the neonate.." J. Nutr.. 1998 February ; 128 (2): 347S-350S. Pubmed PMID: 9478022
- Orellana RA, Wilson FA, Gazzaneo MC, Suryawan A, Davis TA, Nguyen HV "Sepsis and development impede muscle protein synthesis in neonatal pigs by different ribosomal mechanisms.." Pediatr. Res.. 2011 June ; 69 (6): 473-8. Pubmed PMID: 21364490
- Vann RC, Nguyen HV, Reeds PJ, Burrin DG, Fiorotto ML, Steele NC, Deaver DR, Davis TA "Somatotropin increases protein balance by lowering body protein degradation in fed, growing pigs.." Am. J. Physiol. Endocrinol. Metab.. 2000 March ; 278 (3): E477-83. Pubmed PMID: 10710502
- Vann RC, Nguyen HV, Reeds PJ, Steele NC, Deaver DR, Davis TA "Somatotropin increases protein balance independent of insulin's effects on protein metabolism in growing pigs.." Am. J. Physiol. Endocrinol. Metab.. 2000 July ; 279 (1): E1-E10. Pubmed PMID: 10893316
- Davis TA, Bush JA, Vann RC, Suryawan A, Kimball SR, Burrin DG "Somatotropin regulation of protein metabolism in pigs.." J. Anim. Sci.. 2004 82 : E207-213. Pubmed PMID: 15471799
- Bush JA, Wu G, Suryawan A, Nguyen HV, Davis TA "Somatotropin-induced amino acid conservation in pigs involves differential regulation of liver and gut urea cycle enzyme activity.." J. Nutr.. 2002 January ; 132 (1): 59-67. Pubmed PMID: 11773509
- Bush JA, Burrin DG, Suryawan A, O'Connor PM, Nguyen HV, Reeds PJ, Steele NC, Van Goudoever JB, Davis TA "Somatotropin-induced protein anabolism in hindquarters and portal-drained viscera of growing pigs.." Am. J. Physiol. Endocrinol. Metab.. 2003 February ; 284 (2): E302-12. Pubmed PMID: 12388127
- Beckett PR, Hardin DS, Davis TA, Nguyen HV, Wray-Cahen D, Copeland KC "Spectrophometric assay for measuring branched-chain amino acid concentrations: application for measuring the sensitivity of protein metabolism to insulin.." Anal. Biochem.. 1996 August 15; 240 (1): 48-53. Pubmed PMID: 8811878
- Burrin DG, Davis TA, Fiorotto ML, Reeds PJ "Stage of development and fasting affect protein synthetic activity in the gastrointestinal tissues of suckling rats.." J. Nutr.. 1991 July ; 121 (7): 1099-108. Pubmed PMID: 2051230
- Wilson FA, Suryawan A, Gazzaneo MC, Orellana RA, Nguyen HV, Davis TA "Stimulation of muscle protein synthesis by prolonged parenteral infusion of leucine is dependent on amino acid availability in neonatal pigs.." J. Nutr.. 2010 February ; 140 (2): 264-70. Pubmed PMID: 20032489
- Wilson FA, Orellana RA, Suryawan A, Nguyen HV, Jeyapalan AS, Frank J, Davis TA "Stimulation of muscle protein synthesis by somatotropin in pigs is independent of the somatotropin-induced increase in circulating insulin.." Am. J. Physiol. Endocrinol. Metab.. 2008 July ; 295 (1): E187-94. Pubmed PMID: 18460595
- Davis TA, Fiorotto ML, Burrin DG, Reeds PJ, Nguyen HV, Beckett PR, Vann RC, O'Connor PM "Stimulation of protein synthesis by both insulin and amino acids is unique to skeletal muscle in neonatal pigs.." Am. J. Physiol. Endocrinol. Metab.. 2002 April ; 282 (4): E880-90. Pubmed PMID: 11882508
- Suryawan A, Davis TA "The abundance and activation of mTORC1 regulators in skeletal muscle of neonatal pigs are modulated by insulin, amino acids, and age.." J. Appl. Physiol.. 2010 November ; 109 (5): 1448-54. Pubmed PMID: 20724570
- Davis TA, Reeds PJ "The roles of nutrition, development and hormone sensitivity in the regulation of protein metabolism: an overview.." J. Nutr.. 1998 February ; 128 (2): 340S-341S. Pubmed PMID: 9478020
- Bush JA, Kimball SR, O'Connor PM, Suryawan A, Orellana RA, Nguyen HV, Jefferson LS, Davis TA "Translational control of protein synthesis in muscle and liver of growth hormone-treated pigs.." Endocrinology. 2003 April ; 144 (4): 1273-83. Pubmed PMID: 12639910
- Suryawan A, Orellana RA, Fiorotto ML, Davis TA "TRIENNIAL GROWTH SYMPOSIUM: Leucine acts as a nutrient signal to stimulate protein synthesis in neonatal pigs.." J. Anim. Sci.. 2011 July ; 89 (7): 2004-16. Pubmed PMID: 20935141
- Thivierge MC, Bush JA, Suryawan A, Nguyen HV, Orellana RA, Burrin DG, Jahoor F, Davis TA "Whole-body and hindlimb protein breakdown are differentially altered by feeding in neonatal piglets.." J. Nutr.. 2005 June ; 135 (6): 1430-7. Pubmed PMID: 15930448
- Reeds PJ, Burrin DG, Davis TA, Fiorotto ML "Postnatal growth of gut and muscle: competitors or collaborators?." Proc Nutr Soc. 1993 January ; 52 (1): 57-67. Pubmed PMID: 8493277
- Pond WG, Schoknecht PA, Fiorotto ML, Walton L, Tran V, Davis TA, Mersmann HJ "Differential nutrient partitioning in pregnant rat dams fed restricted amounts of a balanced diet versus restricted nonprotein calories." Nutr Res. 1994 14 (7): 1067-1076.
- Beckett PR, Wray-Cahen D, Davis TA, Copeland KC "Enzyme assay for the rapid determination of plasma lysine." Anal. Commun.. 1996 February ; 33 (2): 47059.
- Davis TA, Burrin DG, Fiorotto ML, Nguyen HV. "Protein synthesis in skeletal muscle and jejunum is more responsive to feeding in 7- than in 26-day-old pigs.." Am J Physiol Endocrinol Metab. 1996 270 (5): E802-E809. Pubmed PMID: 8967468
- Burrin DG, Wester TJ, Davis TA, Amick S, Heath JP. "Orally administered IGF-I increases intestinal mucosal growth in formula-fed neonatal pigs.." Am J Physiol Regulatory Integrative Comp Phys. 1996 270 (5): R1085-R1091. Pubmed PMID: 8928910
- Motil KJ, Davis TA, Montandon CM, Wong WW, Klein PD, Reeds PJ. "Whole-body protein turnover in the fed state is reduced in response to dietary protein restriction in lactating women.." Am J Clin Nutr. 1996 64 : 32-39. Pubmed PMID: 8669411
- Davis TA, Fiorotto ML, Burrin DG, Pond WG, Nguyen HV. "Intrauterine growth retardation does not alter the response of protein synthesis to feeding in new born pigs.." Am J Physiol Endocrinol Metab. 1997 272 (5): E877-E884. Pubmed PMID: 9176189
- Fiorotto ML, Davis TA "Food intake alters muscle protein gain with little effect on Na+,K+-ATPase and myosin isoforms in suckled rats.." Am J Physiol Regulatory Integrative Comp Phys. 1997 272 : R1461-R1471. Pubmed PMID: 9176338
- Wray-Cahen D, Beckett PR, Nguyen HV, Davis TA "Insulin-stimulated amino acid utilization during glucose and amino acid clamps decreases with development." Am J Physiol Endocrinol Metab. 1997 273 : E305-E314. Pubmed PMID: 9277383
- Sarwar G, Botting HG, Davis TA, Darling P, Pencharz PB. "Free amino acids in milks of human subjects, other primates and non-primates.." Br J Nutr. 1998 79 (2): 129-131. Pubmed PMID: 9536856
- Kimball SR, Jefferson LS, Nguyen HV, Suryawan A, Bush JA, Davis TA. "Feeding stimulates protein synthesis in muscle and liver of neonatal pigs through an mTOR-dependent process.." Am J Physiol Endocrinol Metab. 2000 279 : E1080-E1087. Pubmed PMID: 11052963
- Davis TA, Suryawan A, Bush JA, O'Connor MJ, Thivierge MC. "Interaction of amino acids and insulin in the regulation of protein metabolism in growing animals.." Can J Anim Sci. 2003 83 (3): 357-364.
- Ramsay TG, Bush JA, McMurty JP, Thivierge MC, Davis TA. "Peripheral leptin administration alters hormone and metabolite levels in the young pig.." Comp Biochem Physiol A Mol Integr Physiol. 2004 138 : 17-25. Pubmed PMID: 15165566
- Wu G, Bazer FW, Davis TA, Jaeger LA, Johnson GA, Kim SW, Knabe DA, Meininger CJ, Spencer TE, Yin U. "Important roles for the arginine-family of amino acids in swine nutrition and production." Livestock Science. 2007 112 (1): 8-22.
- Davis TA "Insulin and amino acids are critical regulators of neonatal muscle growth.." Nutrition Today. 2008 43 (4): 1430149. Pubmed PMID: 19360138
- Davis TA, Suryawan A, Orellana RA, Fiorotto ML, Burrin DG. "Amino acids and insulin are regulators of muscle protein synthesis in neonatal pigs.." Animal. 2010 4 (11): 1790-1796. Pubmed PMID: 21779306
- Fortin M, Julien P, Couture Y, Dubreuil P, Chouinard PY, Latulippe C, Davis TA, Thivierge MC. "Regulation of glucose and protein metabolism in growing steers by long-chain n-3 fatty acids in muscle membrane phospholipids is dose-dependent.." Animal. 2011 4 : 89-101. Pubmed PMID: 22443622
- Suryawan A, Nguyen HV, Almonaci RD, Davis TA "Differential regulation of protein synthesis in skeletal muscle and liver of neonatal pigs by leucine through the mTORC1-dependent pathway.." J Anim Sci Biotech. 2012 3 : 3-12. Pubmed PMID: 22675606
- El-Kadi SW, Gazzaneo MC, Suryawan A, Orellana RA, Torrazza RM, Srivastava N, Kimball SR, Fiorotto ML, Nguyen HV, Davis TA. "Viscera and muscle protein synthesis in neonatal pigs is increased more by intermittent bolus than continuous feeding.." Pediatr Res. 2013 74 (2): 154-162. Pubmed PMID: 23736770
- Boutry C, El-Kadi SW, Suryawan A, Wheatley SR, Orellana RA, Nguyen HV, Davis TA. "Leucine pulses enhance skeletal muscle protein synthesis during continuous feeding in neonatal pigs.." Am J Physiol Endocrinol Metab. 2013 305 (5): E620-E631. Pubmed PMID: 23839523
- Suryawan A, Orellana RA, Nguyen HV, Almonaci RD, Davis TA "Regulation of protein degradation pathways by amino acids and insulin in skeletal muscle of neonatal pigs.." J Anim Sci Biotech. 2014 5 : 1-11. Pubmed PMID: 24438646
- Wheatley SM, El-Kadi SW, Suryawan A, Boutry C, Orellana RA, Nguyen HV, Davis SR, Davis TA. "Protein synthesis in skeletal muscle of neonates is enhanced by administration of β-hydroxy-β-methylbutyrate.." Am J Physiol Endocrinol Metab. 2014 306 : E91-E99.. Pubmed PMID: 24192287
- Fiorotto ML, Davis TA, Sosa H, Villegas-Montoya C, Fleischman R. "Ribosome abundance regulates the recovery of skeletal muscle protein mass upon recuperation from postnatal undernutrition in mice.." J Physiol. 2014 592 : 5269-5286. Pubmed PMID: 25239457
- Davis TA, Fiorotto ML, Suryawan A. "Bolus versus continuous feeding to optimize anabolism in neonates.." Curr Opin Clin Nutr Metab Care. 2015 18 : 102-108. Pubmed PMID: 25474017
- Columbus DA, Fiorotto ML, Davis TA. "Leucine is a primary regulator of muscle protein synthesis in neonates.." Amino Acids. 2015 47 : 259-270. Pubmed PMID: 25408462
- Layman DK, Anthony TG, Rasmussen BB, Adams SH, Lynch CJ, Brinkworth GD, Davis TA. "Defining meal requirements for protein to optimize metabolic roles of amino acids.." Am J Clin Nutr. 2015 101 : 1330S-1339S. Pubmed PMID: 25926513
- 137. Reynolds LP, Wulster-Radcliffe M, Aaron DK, Davis TA. "Importance of animals in agricultural sustainability and food security.." J Nutr. 2015 145 : 1377-1379. Pubmed PMID: 25972529
- 138. Columbus DA, Steinhoff-Wagner J, Suryawan A, Nguyen HV, Hernandez-Garcia A, Fiorotto ML, Davis TA. "Impact of prolonged leucine supplementation on protein synthesis and lean growth in neonatal pigs.." Am J Physiol Endocrinol Metab. 2015 309 : E601-E610. Pubmed PMID: 26374834
- 139. Manjarin R, Columbus DA, Fiorotto ML, Suryawan A, Nguyen HV, Hernandez-Garcia AD, Hoang N-M, and Davis TA. "Leucine supplementation of a protein and energy restricted diet enhances mTORC1 activation but not muscle protein synthesis in neonatal pigs.." Amino Acids. 2016 48 (1): 257-267. Pubmed PMID: 26334346
- 140. Boutry C, El-Kadi SW, Suryawan A, Steinhoff-Wagner J, Stoll B, Orellana RA, Nguyen HV, Kimball SR, Fiorotto ML, and Davis TA. "Pulsatile delivery of a leucine supplement during long-term continuous enteral feeding enhances lean growth in term neonatal pigs.." Am J Physiol Endocrinol Metab. 2016 310 : E699-E713. Pubmed PMID: 26884386
- Davis TA, Karl IE "Resistance of protein and glucose metabolism to insulin in denervated rat muscle.." Biochem J. 1988 254 (3): 667-675. Pubmed PMID: 3196284
- Bales CW, Davis TA, Beauchene RE "Long-term protein and calorie restriction: alterations in nucleic acid levels of organs of male rats.." Exp Gerontol. 1988 23 (3): 189-196. Pubmed PMID: 2462506
- Heifets M, Davis TA, Tegtmeyer E, Klahr S "Exercise training ameliorates progressive renal disease in rats with subtotal nephrectomy.." Kidney Int. 1987 32 (6): 815-820. Pubmed PMID: 3430965
- Davis TA, Klahr S, Karl IE. "Insulin-stimulated protein metabolism in chronic azotemia and exercise.." Am J Physiol Renal Physiol. 1987 253 : F164-f169. Pubmed PMID: 3300369
- Davis TA, Klahr S, Karl IE "Glucose metabolism in muscle of sedentary and exercised rats with azotemia.." Am J Physiol Renal Physiol. 1987 252 : F138-F145. Pubmed PMID: 3544866
- Davis TA, Karl IE "Response of muscle protein turnover to insulin after acute exercise and training.." Biochem J. 1986 240 (3): 651-657. Pubmed PMID: 3548710
- 8. Davis TA, Klahr S, Tegtmeyer ED, Osborne DF, Howard TL, Karl IE. "Glucose metabolism in epitrochlearis muscle of acutely exercised and trained rats.." Am J Physiol. 1986 250 : E137-E143. Pubmed PMID: 3953787
- 7. Davis TA, Anderson EC, Ginsberg AV, and Goldberg AP. "Weight loss improves lipoprotein lipid profiles in patients with hypercholesterolemia.." J Lab Clin Med. 1985 106 (4): 447-454. Pubmed PMID: 4045301
- Harter HR, Davis TA, Karl IE "Enhanced muscle protein catabolism in uremia.." Adv Exp Med Biol. 1984 167 : 577-569. Pubmed PMID: 6369920
- Davis TA, Karl IE, Goldberg AP, Harter HR. "Effects of exercise training on muscle protein catabolism in uremia.." Kidney Int. 1983 24 : S52-S57. Pubmed PMID: 6376921
- Davis TA, Bales CW, Beauchene RE. "Differential effects of dietary caloric and protein restriction in the aging rat.." Exp Gerontol. 1983 18 (6): 427-435. Pubmed PMID: 6673988
- Carney RM, Schechter K, and Davis TA "Improving adherence to blood glucose testing in insulin-dependent diabetic children.." Behav Ther. 1983 (14): 247-254.
- 6. Davis TA, Karl IE, Tegtmeyer ED, Osborne DF, Klahr S, and Harter HR. "Muscle protein turnover: effects of exercise training and renal insufficiency.." Am J Physiol Endocrinol Metab. 1985 248 (3): E337-E345. Pubmed PMID: 3883805
- Davis TA, Karl IE, Tegtmeyer ED, Osborne DF, Klahr S, and Harter HR "Muscle protein turnover: effects of exercise training and renal insufficiency.." Am J Physiol Endocrinol Metab. 1985 : E337-E345. Pubmed PMID: 3883805
- Suryawan A and Davis TA "Amino acid- and insulin-induced activation of mTORC1 in neonatal piglet skeletal muscle involves Sestrin2-GATOR2, Rag A/C-mTOR, and RHEB-mTOR complex formation.." J Nutr. 2018 148 : 825-833. Pubmed PMID: 29796625
- Hernandez-García A, Manjarín R, Suryawan A, Nguyen HV, Davis TA, and Orellana RA "Amino acids, independent of insulin, attenuate skeletal muscle autophagy in neonatal pigs during endotoxemia.." Pediatr Res. 2016 80 (3): 448-451. Pubmed PMID: 27064245
- Kao M, Columbus DA, Suryawan A, Steinhoff-Wagner J, Hernandez-Garcia A, Nguyen HV, Fiorotto ML, and Davis TA "Enteral β-hydroxy-β-methylbutyrate increases protein synthesis in skeletal muscle of neonatal pigs." 2016 310 (11): E1072-84. Pubmed PMID: 16278252
- Manjarin R, Suryawan A, Koo SJ, Wilson FA, Nguyen HV, Davis TA, and Orellana RA "Insulin modulates energy and substrate sensing and protein catabolism induced by chronic peritonitis in skeletal muscle of neonatal pigs.." Pediatr Res. 80 (5): 744-752. Pubmed PMID: 2750897
- Hernandez-Garcia AD, Manjarin R, Columbus D, Nguyen HV, Suryawan A, Orellana R, and Davis TA "Leucine supplementation stimulates muscle protein synthesis in newborn pigs during acute endotoxemia.." Am J Physiol Endocrinol Metab. 2016 311 (4): E791-E801. Pubmed PMID: 27624100
- Escobar J, Frank JW, Suryawan A, Nguyen HV, and Davis TA "Regulation of cardiac and skeletal muscle protein synthesis by branched-chain amino acids in neonates.." Am J Physiol Endocrinol Metab. 2006 (290): E612-E21. Pubmed PMID: 16278252
- Beauchene RE and Davis TA "The nutritional status of the aged in the USA.." Age. 1979 2 : 23-8.
- Fiorotto ML and Davis TA "Critical windows for the programming effects of early-life nutrition on skeletal muscle mass.." Nestlé Nutr Inst Workshop Ser. 2018 (89): 25-35. Pubmed PMID: 29991029
- El-Kadi S, Boutry C, Suryawan A, Nguyen HV, Kimball SR, Fiorotto ML, and Davis TA "Intermittent bolus feeding enhances organ growth more than continuous feeding in a neonatal piglet model.." Curr Dev Nutr 4. 2021 4 (12):
- Manjarín R, Boutry-Regard C, Suryawan A, Canovas A, Piccolo BD, Maj M, Ismail MA, Nguyen H, Fiorotto ML, and Davis TA "Intermittent leucine pulses during continuous feeding alters novel components involved in skeletal muscle growth of neonatal pigs.." Amino Acids. 2020 (52): 1319-1335.
- Rudar M, Columbus DA, Steinhoff-Wagner J, Suryawan A, Nguyen HV, Fleischmann R, Davis TA, and Fiorotto ML "Leucine supplementation does not restore diminished satellite cell abundance and myonuclear accretion induced by protein restriction in neonatal pig skeletal muscle.." J Nutr. 2020 150 (1): 22-30. Pubmed PMID: 31518419
- Manjarín R, Columbus DA, Solis J, Hernandez-García A, Suryawan A, Nguyen HV, McGuckin MM, Jimenez RT, Fiorotto ML, and Davis TA "Short and long-term effect of leucine and BCAA inclusion in a reduced protein and energy diet on muscle protein metabolism in neonatal pigs.." Amino Acids. 2018 50 (7): 943-959. Pubmed PMID: 29728917
- Suryawan A, Nguyen HV, Almonaci RD, Davis TA. "Abundance of amino acids transporters involved in mTORC1 activation in skeletal muscle of neonatal pigs is developmentally regulated.." Amino Acids. 2013 45 : 523-530. Pubmed PMID: 22643846
- Wilson FA, Suryawan A, Orellana RA, Gazzaneo MC, Nguyen HV, Davis TA "Differential effects of long-term leucine infusion on tissue protein synthesis in neonatal pigs.." Amino Acids. 2011 January ; 40 (1): 157-65. Pubmed PMID: 20505962
Memberships
- American Society for Nutrition
- American Society of Animal Science
- American Physiological Society
- Endocrine Society
- American Diabetes Association
Funding
- Leucine and HMB Supplementation in Early Life to Promote Muscle Growth at the Expense of Adipose Deposition - #R01HD099080 (09/01/2019 - 07/31/2022) Grant funding from NIH
- Regulation of Neonatal Muscle Protein Synthesis - #9 R01 HD085573-18 (04/15/2016 - 03/31/2022) Grant funding from NIH
- Leucine Supplementation to Promote Lean Growth in Early Life - #1 R01 HD072891 (09/20/2012 - 06/30/2017) Grant funding from NIH
- Early Feeding Practices, Growth and Health - #USDA CRIS 6250-51000-055-00D-3 (05/01/2014 - 04/30/2019) Grant funding from USDA
- Leucine Supplementation to Promote Lean Growth in Early Life - #USDA NIFA 2013-67015-20438 (01/15/2013 - 01/14/2017) Grant funding from USDA
- Enteral ZA26 to Promote Protein Synthesis in the Neonatal Piglet Model (01/01/2013 - 12/31/2016) Grant funding from Abbott
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