Shixia Huang, Ph.D.
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Shixia Huang, Ph.D.
Associate Professor
Positions
- Associate Professor
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Mol & Cell Biology
Baylor College of Medicine
Houston, TX US
- Director, Antibody-Based Proteomics Core
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Advanced Technology Cores
Baylor College of Medicine
Houston, Texas United States
- Associate Professor
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Education, Innovation & Technology
Baylor College of Medicine
Houston, Texas USA
- Faculty Senator
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Baylor College of Medicine
- Inclusion and Excellence Council
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Baylor College of Medicine
- Member
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Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Education
- PhD from Michigan State University
- 06/1997 - East Lansing, Michigan United States
- Genetics
- Postdoctoral Fellowship at National Cancer Institute
- 05/2000 - Bethesda, Maryland United States
- Postdoctoral Fellowship at Memorial Sloan-Kettering Cancer Center
- 03/2003 - New York, New York United States
- MS from Yangzhou University
- Yangzhou, Jiangsu China, People's Rep
- Infectious Disease & Preventive Veterinary Medicine
- BS from Hunan Agricultural University
- Changsha, Hunan China, People's Rep
- Veterinary Medicine
Websites
The Antibody-based Proteomics Core provides cutting-edge antibody-based proteomic platforms for both validation and protein biomarker discovery, particularly for low abundance regulatory proteins and activation states of proteins with phosphorylated antibodies.
Selected Publications
- Huang S, Li Y, Chen Y, Podsypanina K, Chamorro M, Olshen AB, Desai KV, Tann A, Petersen D, Green JE, Varmus HE "Changes in gene expression during the development of mammary tumors in MMTV-Wnt-1 transgenic mice.." Genome Biol.. 2005 6 (10): R84. Pubmed PMID: 16207355
- Huang S, Flanders KC, Roberts AB "Characterization of the mouse Smad1 gene and its expression pattern in adult mouse tissues.." Gene. 2000 November 27; 258 (41276): 43-53. Pubmed PMID: 11111041
- Li Y, Welm B, Podsypanina K, Huang S, Chamorro M, Zhang X, Rowlands T, Egeblad M, Cowin P, Werb Z, Tan LK, Rosen JM, Varmus HE "Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells.." Proc. Natl. Acad. Sci. U.S.A.. 2003 December 23; 100 (26): 15853-8. Pubmed PMID: 14668450
- Lu, H.-Y., Xiong, j., Perera, D. N., Rajapakshe, K., Wang, X., Costello M., Holloway K. R., Ramos, C., Grimm, S. L., Wulfkuhle, J., Coarfa, C., Edwards, D. P., Zhu, M. X., and Huang, S. "High-throughput Evaluation of Metabolic Activities Using Reverse Phase Protein Array (RPPA) Technology." Book chapter in: Tong, Q., 1st ed. Neuronal Signaling in Metabolism. 2021 June ; 1st Edition : 25.
- Coarfa C, Grimm SL, Rajapakshe K, Perera D, Lu HY, Wang X, Christensen KR, Mo Q, Edwards DP, Huang S. "Reverse-Phase Protein Array: Technology, Application, Data Processing, and Integration." J Biomol Tech.. 2021 April ; 32 (1): 15-29. Pubmed PMID: 34025221
- Dong J, Huang S, Caikovski M, Ji S, McGrath A, Custorio MG, Creighton CJ, Maliakkal P, Bogoslovskaia E, Du Z, Zhang X, Lewis MT, Sablitzky F, Brisken C, Li Y "ID4 regulates mammary gland development by suppressing p38MAPK activity.." Development. 2011 December ; 138 (23): 5247-56. Pubmed PMID: 22069192
- Huang S, Chen Y, Podsypanina K, Li Y "Comparison of expression profiles of metastatic versus primary mammary tumors in MMTV-Wnt-1 and MMTV-Neu transgenic mice.." Neoplasia. 2008 February ; 10 (2): 118-24. Pubmed PMID: 18283333
- Huang S, Tang B, Usoskin D, Lechleider RJ, Jamin SP, Li C, Anzano MA, Ebendal T, Deng C, Roberts AB "Conditional knockout of the Smad1 gene.." Genesis. 2002 February ; 32 (2): 76-9. Pubmed PMID: 11857782
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