Baylor College of Medicine

Baylor Faculty Awarded R01 Grant to Promote Antibiotic Stewardship


Dr. Barbara W. Trautner, professor, and director of Health Services Research and Research Administration in the Department of Surgery, and Dr. Larissa Grigoryan, assistant professor of Family and Community Medicine, have received a R01 grant from the Agency for Healthcare Research and Quality (AHRQ). Their project is titled, “Reducing Use of Antibiotics without a Prescription among Outpatients in a Safety Net Healthcare System.” The premise of the study is that taking antibiotics without a health care provider’s prescription or guidance puts the person at risk for development of antibiotic-resistant infections, allergic reactions, disturbance of normal gut flora, and other harms. Low-income populations seen in safety-net primary care clinics may suffer disproportionately from the practice of taking antibiotics without a prescription. The team will explore why this occurs so that they can help people avoid harms from unsafe use of antibiotics and prevent the spread of antibiotic resistance.


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Dr. Barbara W. Trautner

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Dr. Trautner’s primary research interest is the development of antibiotic-sparing strategies for the prevention of catheter-associated urinary tract infection. She has worked in this area for over 19 years. While on NIH and then VA career development award support, Dr. Trautner obtained her Ph.D. in clinical investigation from Baylor College of Medicine. Her observations of successively more resistant urinary pathogens emerging in her own patients in response to successive rounds of unnecessary antibiotics led to her research passion for antibiotic stewardship.


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Dr. Larissa Grigoryan

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Dr. Grigoryan’s primary research interest is antimicrobial stewardship. She obtained her PhD in epidemiology from University of Groningen, The Netherlands. Dr. Grigoryan’s work included two European Union funded studies on inappropriate antibiotic use in 19 European countries. Currently, she has funding support from Antibacterial Resistance Leadership Group of NIH and VA HSR&D on improving antibiotic stewardship for urinary tract infections.

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