Analyzing both the entire set of genes and all the proteins produced by colon cancer tissues from patient samples has revealed a more comprehensive view of the tumor that points at novel cancer biological mechanisms and possible new therapeutic strategies.
A multidisciplinary, international team of scientists has been awarded Cancer Research UK’s Grand Challenge, an ambitious series of £20 million global grants tackling some of the toughest questions in cancer research.
A team of scientists found that the Transforming Growth Factor beta (TGF-beta) signaling pathway in uterine cells protects against uterine cancer by suppressing the overgrowth and transformation into cancer cells of the endometrium.
A team led by researchers at Baylor College of Medicine and the University of Texas at Austin has applied an unconventional approach that used bacteria to discover human proteins that can lead to DNA damage and promote cancer.
A study reveals that when Dna2 is absent, small DNA fragments jump from all over the genome into chromosome breaks. This novel mechanism may explain similar events commonly seen in cancer or during antibody diversification.