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BCM - Baylor College of Medicine

Giving life to possible

National School of Tropical Medicine

Research

The "neglected tropical diseases" and "neglected infections of poverty" are the most common infections of the world's poorest people; together they trap people in poverty through their adverse impact on child development, pregnancy outcome and worker productivity.

What are Neglected Tropical Diseases and Neglected Infections of Poverty?

A New Generation of NTD Control Tools

The National School of Tropical Medicine conducts a comprehensive research and development program for producing a new generation of drugs, diagnostics and vaccines for the Neglected Tropical Diseases (NTDs) and Neglected Infections of Poverty (NIoPs), as well as fundamental and applied research against these diseases.

In the area of NTD vaccine development, Texas Children's Hospital in partnership with the National School of Tropical Medicine has established the Sabin Vaccine Institute & Texas Children's Hospital Center for Vaccine Development

Over the last 10 years the Sabin Vaccine Institute Product Development Partnership has led the development of new vaccines to combat NTDs. Through the activities of the Sabin Vaccine Institute PDP, a new human hookworm vaccine is in phase 1 clinical trials, while a schistosomiasis vaccine  has undergone clinical good manufacturing practices (cGMP) and is awaiting regulatory approvals to initiate  clinical testing. Vaccines against leishmaniasis, Chagas disease, and other soil-transmitted helminths are in development.