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news › bcm-partners-with-largest-autism-study-celebrating-five-years-of-genetic-research
… SPARK catalyzes advances in autism science in two major ways. Close to 100,000 study participants have provided DNA …
research › faculty-labs › vaishnav-krishnan-lab
… home cage behavioral monitoring technology to understand how interictal behavior is directly modulated by latent … (23-24h). Thus, we make no assumptions about when or how a manipulation (genetic or pharmacological) may be …
news › link-found-between-feeding-memory-brain-areas
… validated the newly discovered circuits in different ways. “We applied both optogenetics and chemogenetics … and Smith–Magenis syndromes,” Liu explains. “We have always suspected that mutations of this gene could cause …
departments › ... › residents
… and supportive of my career development every step of the way. …
news › circadian-clock-in-heart-failure
… acid use can be controlled by lipid-sensing metabolic pathways. We hypothesized that if we fed the Rev-erbα/β knockout mice more lipids, maybe the lipid-sensing pathways would be activated, override the defect and … medications can help restore the altered metabolic pathways, it was important to give the drugs aligned with the …
research › ... › circular-rnas-unexpected-outputs-of-protein-coding-genes
… and purification using RNase R by identifying a way to better remove linear RNAs containing G-quadruplexes … J.E. (2018) A length-dependent evolutionarily conserved pathway controls nuclear export of circular RNAs. Genes Dev …
news › close-up-on-aging-reveals-different-cells-age-at-different-pace
… ages, organ function progressively declines and the risk for a wide range of diseases, including cardiovascular … intense area of research as it will potentially illuminate ways to promote healthy aging. Researchers at Baylor … type-specific patterns. AFCA provides a valuable resource for researchers in the fruit fly and aging communities as a …
news › dr-hugo-bellen-named-recipient-of-the-2024-gruber-genetics-prize
… biological processes to how disruptions in these pathways lead to rare and common brain disorders and, finally, to finding new ways to diagnose and treat these conditions. … He elucidated the role of several important genes and pathways involved in these fundamental processes and, given how …
news › pfa-ependymoma-brain-tumors-display-unique-3d-genome-features-that-could-be-exploited-therapeutically
… of posterior fossa group A (PFA) ependymoma, a difficult-to-treat brain tumor diagnosed in very young children. The … University and collaborating institutions, could lead to the development of new treatments. “PFA ependymomas are … distances. TULIPs at opposite ends of a chromosome can find ways to interact with surprising strength,” Gallo said. …
news › researchers-connect-the-dots-between-cause-effect-events-in-alzheimers-disease
… disease while others may protect against it. “One important way to investigate the molecular cascade leading to … Alzheimer’s disease pinpoints specific driver genes and pathways worthy of further study as potential therapeutic …