research › ... › publications
… L, Goodell MA, … Rau RE … . Modeling IKZF1 lesions in B-ALL reveals distinct chemosensitivity patterns and potential … CV, Kim SB, Ruau D, Zhang X, Zhou T, Zhou M, Rebel VI, Challen GA, Gottgens B, Lee JS, … Rau R … , Li W, Goodell MA. … Huso D, McIntyre E, Clohessy JG, Reschke M, Pandolfi PP, Small D, Brown P. NPMc+ cooperates with Flt3/ITD mutations to …
news › neuroprotective-mechanism-altered-by-alzheimers-disease-risk-genes
… found that ROS, together with amyloid-beta, the main component in the plaques found in the brains of people with … apolipoprotein APOE4. “We found that APOE4 is practically unable to transfer lipids to glia, while other two … One reason we are interested in this comes from human studies that show that genes involved in both import and export …
research › ... › facilities-and-resources
… within the Texas Medical Center (TMC), a nearly 1,000-acre complex, housing 59 member institutions. The Center was … Thermo XR4-Pro, two Thermo XPro, two Thermo Sorvall ST8, and a Thermo Heraeus Multifuge X1R. Protein … conducting high throughput metagenomic and microbiome studies. Sample Intake: For sample receiving and tracking, the …
research › ... › research
… S -glutathionylation. These important functions are dynamically regulated by the intracellular concentration and … in living cells ( ACS Chem Bio 2015 ). We developed a computational model to predict the thermodynamics and … in a breast cancer mouse xenograft model. In toxicology studies, we found that SI-2 causes no observable acute or …
healthcare › ... › diabetic-foot-limb-salvage
… is a multifaceted condition that can result in severe complications, including limb loss. Two major concerns are … diabetes or kidney failure: Chronic conditions that compromise circulation and healing. Current or former heavy … give patients access to the latest, state-of-the-art, minimally invasive vascular interventions, open surgery, wound …
education › national-school-of-tropical-medicine › what-is-tropical-medicine
… related disorders in malnutrition and even some non-communicable diseases. … Diseases of Poverty … First and … diseases are diseases of poverty. They are the most common afflictions of the “bottom billion” the 1.3 billion … Bank poverty level. Although tropical diseases are generally thought of as exclusively occurring in developing …
academic-centers › ... › news
… of Space Travel and Research (GENESTAR) manual, a comprehensive protocol for collecting, processing and … commercial spaceflight participants tailored to support all current and anticipated biological and genomic … hibernate? How scientists are racing to unlock a sci-fi superpower … August 19 … – TRISH research is featured in …
departments › ... › projects-conducted-by-current-fellows
… Tetrahydrocannabinol (THC) containing products have become more readily available in Texas over the past several years with changes in legislation. Various studies have been published on the effects of THC exposure in … of healthcare related to THC exposures. Dr. Alavi additionally strives to assess the social aspects of cannabis …
research › ... › projects
… anatomy, the hippocampus is one of the most heavily studied regions of the mammalian brain. While a trisynaptic … hippocampal principal cells has long been established, a complete census of its GABAergic cell types and their … circuit components specific to this circuit endow it with superb computational capabilities for complex cognitive …
departments › ... › alcoholism-and-addictive-disorders
… (ICTR) and as a member of the Baylor College of Medicine Comprehensive Cancer Center, Dr. Kosten focuses attention on … wide range of cancers whose rates are still growing, especially among minority populations. Recent funding challenges … cocaine vaccine that will move forward into human studies here at Baylor. In collaborations with Baylor …