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news › oops-after-ten-years-and-1000-studies-epigeneticists-uncover-trouble-in-their-tool-box
… began conducting large genome-wide association studies to identify genomic regions linked to human disease. In … researchers at Baylor College of Medicine reveals that the commercial tool that has been the workhorse for these studies is actually not appropriate for population epigenetics. “Many …
research › ... › publications
… All models available on our NIH 3D Repository Page … M.P., Le, E.A., Tak, A.L., Chacko, S.K. (2024). A Comprehensive UHPLC-MS/MS and Extraction Method for Spinach … Cooperstone, J.L. (2019). Analysis of tomato carotenoids: comparing extraction and chromatographic methods . J of AOAC …
news › protein-eif4a-emerges-as-a-potential-achilles-heel-for-triple-negative-breast-cancer
… poor prognosis and limited therapeutic targets, has been challenging. Responding to this need for better treatments, … in TNBC that could lead to novel therapies and improved outcomes for this devastating condition. The team reports in … promising results,” Zhao said. “We are hoping that our studies could help inform future clinical trials and positively …
news › common-olympic-injuries
… The 2024 Olympic Games are top of mind for people globally. While the athletes make their sports look effortless, … A Baylor College of Medicine orthopedic surgeon details common injuries among fan-favorite Olympic sports. … … improper landings. Achilles ruptures and strains also are common, devastating injuries resulting from explosive …
news › dr-hugo-bellen-named-recipient-of-the-2024-gruber-genetics-prize
… to how disruptions in these pathways lead to rare and common brain disorders and, finally, to finding new ways to diagnose and treat these … how the peripheral nervous system develops and how neurons communicate with one another. He elucidated the role of …
news › researchers-discovered-molecular-events-leading-to-rett-syndrome
… – many ‘harmonies’ are played simultaneously creating a complex composition. It can be challenging to distinguish the harmonies emerging from the …
news › study-reveals-new-indicators-for-her2-breast-cancer-response-to-therapy
… best possible treatment. Their decision is informed by a comprehensive molecular profile of the patient’s cancer … that drive treatment response and resistance and potentially improve precision medicine strategies.” “Being able to … from all participants before therapy began. Prior studies using these biopsies focused on RNA and DNA analyses …
departments › ... › research
… diagnostic facility. This general laboratory work area accommodates tissue culture and radioactive work as well as … and intracellular lymphocyte phenotyping, functional studies (LPA) and neutrophil oxidative burst studies. The … even includes the first gated-stimulated emission-depleted super-resolution microscope in the United States. This …
academic-centers › ... › protocols-workflow
… and use that to perform total protein normalization across all the samples. The normalization method is described … antibody (15 min) TBST (5 min) SABC (Streptavidin-Biotin Complex) TBST (5 min) TSA reagent (15 min) TBST (5 min) … at 0 to 100% dilution for tyrosine phosphorylated antibodies. • Cell lysates of Calyculin A-treated Jurkat …
research › ... › lab-members
… demonstrate that over-expression of SIMl protects against diet-induced obesity via gene-regulated actions upon the … rodent behaviors to model human neurologic diseases. He accomplished this by performing research relating to the role … mutation in the SHANK3 gene, this clinical entity enthralled Dr. Holder, leading him to question the underlying …
