about-us › ... › organ-donation-policy
… someone is added to the national transplant waiting list. Unfortunately,  nearly half  of all listed candidates will die … and that innovative approaches are crucial to increase the number of living donors. Specifically, we believe there is a … reviews each OPO based on self-reported data to ensure compliance. A study from the  University of Pennsylvania …
research › ... › comprehensive-lab-animal-monitoring-system
… Measurement Request Protocol  and CLAMS Use and Measures for information about the access and use of this system. … … broken by the mouse, and this sends signals to the central computer. The beams can detect movement along both the X … to include free running wheels. The system records the number of revolutions, distance, and speed run, and the time …
research › ... › projects
… HL089598) … Postoperative atrial fibrillation (poAF) is a common complication of cardiothoracic surgery with an … morbidity and mortality, and is an important risk factor for atrial fibrillation (AF). Very little remains known … genome editing can be used to specifically reduce the number of mutant monomers in RyR2 channel complexes or to …
news › mesoamerican-nephropathy-outbreak-linked-to-nickel-toxicity
For more than 20 years, an epidemic of chronic kidney … of unknown origin has severely affected specific coastal communities along South America’s Pacific coastline from … were put in place, we noticed a dramatic reduction in the number of new cases, an indication that we are moving in the …
news › novel-gene-variants-that-modify-risk-of-late-onset-alzheimers-disease-discovered
… Late-onset Alzheimer’s disease (LOAD) is the most common form of dementia in the elderly, affecting almost 44 … seems to have compensated for a relatively small number of patients (just 480) in this study, which is much …
academic-centers › ... › clinical-trials-support
… Clinical Trials for cancer are research studies that test the safety and … enrolled in clinical research, posing a challenge for outcome interpretation as people of different ages, races, and … English subtitles ~6 minutes). COE has also developed a number of educational videos on the importance of …
news › fruit-fly-study-uncovers-functional-significance-of-gene-mutations-associated-with-autism
… (ASD) by the age of 8, according to the 2018  Centers for Disease Control and Prevention surveillance . How a … of rare disease due to a gene called GLRA2.  “ASDs include complex neurodevelopmental conditions with impairments in … behavioral changes in the flies,” Andrews said. “We found a number of human genes with ASD variants that altered …
news › global-collaboration-mapping-the-whole-human-brain
… by Dr. Ed Lein , senior investigator at the Allen Institute for Brain Science, a division of the Allen Institute, and … works – we have to open it up and look at the different components to see how they are connected and what they do. … National Institutes of Health BRAIN Initiative under Award Numbers UM1MH130981, U01MH130907, U01MH130962, U24MH130918, …
news › novel-approach-prevents-liver-damage-in-animal-models-of-alagille-syndrome
… focus on delaying disease progression; the only cure for liver disease in Alagille syndrome is liver … syndrome, infections, toxins or injuries can reduce the number of ducts in the biliary tree, sometimes to less than … biliary tree. The team worked with Ionis Pharmaceuticals, a company that has pioneered the usage of antisense …
news › cow-milk-vs-alternative-milk-whats-the-best
… milks on the market, consumers have endless options when it comes to choosing milk to quench their thirst, make their … is less heart healthy than unsaturated fats, you can opt for skim or nonfat milk for a less fatty option.   “All of … sugars, so check the nutrition facts to understand the number of grams of added sugar.   … Choosing the right milk …
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