About the Lab
Cardiac arrhythmias severely affect cardiac performance and, in some cases, are lethal. Arrhythmias can result from dysfunctional ion channels located on the plasma membrane or abnormal intracellular calcium handling. Emerging evidence suggests that risk factors for arrhythmias, such as inflammation, obesity, hypertension, etc. can modify the function of cardiac ion channels and calcium handling proteins via transcriptional or posttranscriptional mechanisms. The goal of our research is to elucidate the mechanistic link between these risk factors and the pathophysiology of cardiac arrhythmias, in order to develop novel therapeutic targets for arrhythmic patients.
The lab is funded by research grants from the National Institutes of Health. Trainees will also receive a fellowship from the American Heart Association. A postdoctoral position is available to motivated individuals who have a training background in one or more of the following areas: cardiology, electrophysiology, cell biology, and molecular biology.