Sang Jun Han Lab


About the Lab


Endometriosis is classically defined as the presence of endometrial glands and stroma outside of the endometrial lining and uterine musculature. With an estimated frequency of 5-10 percent among women of reproductive age, endometriosis is a common gynecologic disorder. However, the molecular etiology of endometriosis is not clear, yet.

The goal of our laboratory is to identify and investigate how molecular alternations of nuclear receptors and/or steroid receptor coactivators involve in the pathogenesis of women’s reproductive diseases, specifically Endometriosis and Endometriosis-associated diseases.

To achieve this goal, we have generated lots of genetic altered mouse models, mouse model of surgically induced endometriosis by auto- or hetero-transplantation of endometrial tissues, various genetic modified immortalized human endometrial epithelial and stromal cell lines and in vivo endometriosis imaging system.