Positions
- Associate Professor
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Pediatrics-Nutrition
Baylor College of Medicine
Houston, TX, US
Addresses
- Children's Nutrition Research Center (Lab)
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Room: CNRC-10018
Houston, TX, 77030
United States
- Children's Nutrition Research Center (Office)
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Room: CNRC-10018
Houston, TX, 77030
United States
Education
- Postdoctoral Fellowship at University Of California, San Francisco
- 06/2010 - San Francisco, California, United States
- PhD from University Of Texas At Austin
- 12/2002 - Austin, Texas, United States
Professional Interests
- Developmental biology, adipose tissue biology, stem/progenitor cells
Professional Statement
Dysregulation of the development of progenitor cells during fetal development, early childhood, or even adulthood can significantly contribute to congenital malformations and the development of chronic diseases, such as heart disease, obesity, and type II diabetes. My research program focuses on understanding the origin of adipocytes, developing novel strategies to trace and isolate different types of adipocyte progenitor cells, and investigating the nutritional control of the development and function of these progenitor cells under physiological and pathological conditions.
Websites
Selected Publications
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Kaneko K, Fu Y, Lin HY, Cordonier ELStypulkowski E, Feng Q, Joseph I, Farrell V, Flores J, Yu S, Sakamori R, Sun J, Bandyopadhyay S, Das S, Dobrowolski R, Bonder EM, Chen MH, Gao N.. " Rab8 attenuates Wnt signaling and is required for mesenchymal differentiation into adipocytes. " J Biol Chem.. 2021 Mar 1; 100488.
Pubmed PMID: 33662399. -
Mo Q, Salley J, Roshan T, Baer LA, May FJ, Jaehnig EJ, Lehnig AC, Guo X, Tong Q, Nuotio-Antar AM, Shamsi F, Tseng YH, Stanford KI, Chen MH.. " . Identification and characterization of a supraclavicular brown adipose tissue in mice. " JCI Insight. 2017 Jun 2; 2 (11) : e93166.
Pubmed PMID: 28570265. -
Nosavanh L, Yu DH, Jaehnig EJ, Tong Q, Shen L, Chen MH.. " Cell-autonomous activation of Hedgehog signaling inhibits brown adipose tissue development. " Proc Natl Acad Sci U S A. 2015 Apr 21; 112 (16) : 5069-74.
Pubmed PMID: 25848030. -
2. Chen M-H, Wilson CW, Li YJ, Law KK, Lu C-S, Gacayan R, Zhang X, Hui C-C, Chuang P-T. " Cilium independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved.. " Genes Dev. 2009 ; 23 (16) : 1901-1928.
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