Positions

Associate Professor
Pharmacology and Chemical Biology
Baylor College of Medicine
Houston, TX, US
Member
Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas, United States

Education

Postdoctoral Fellowship at University Of California, San Diego
Biology
PhD from University Of California, San Diego
Chemistry
BS from University Of California, San Diego
Biology

Honors & Awards

Service Award T32 CA09532
Best Poster
Best Poster and Selected Presentation
Postdoctoral Fellow
Protein Chemistry Grant DK07233
Postdoctoral Fellow
Protein Chemistry Grant DK07233
Postdoctoral Fellow
Protein Chemistry Grant DK07233
Postdoctoral Fellow
Protein Chemistry Grant DK07233

Selected Publications

  • Choel Kim, Cecilia Y. Cheng, Adrian S. Saldanha, Susan S. Taylor. "PKA-I Holoenzyme Structure: Dynamic Conformational Change of RI Reveals Mechanism for cAMP-dependent Activation." Cell. 2007;130:1032-1043.
  • Francis S. Kinderman*, Choel Kim*, Sventja von Daake, Bao Q. Pham, Glen Spraggon, Patricia A. Jennings, and Susan S. Taylor. "A Dynamic Mechanism for AKAP Binding to RII Isoforms of cAMP-Dependent Protein Kinase." Molecular Cell. 2006;24:397-408.
  • Choel Kim, Nguyen-Huu Xuong, and Susan S. Taylor. "Crystal Structure of a Complex between the Catalytic and Regulatory (RI) Subunits of PKA." Science. 2005;307:690-696.
  • Simon H. Brown, Choel Kim, Susan S. Taylor. "Crystal Structure of Protein Kinase A bound to Type II Regulatory Subunit Mimics a Transition State." J.Mol.Biol. 2009;393(5):1070-82.
  • Justin Gullingsrud, Choel Kim, Susan S. Taylor and J. Andrew McCammon. "Dynamic Binding of PKA Regulatory subunit (RI)." Structure. 2006;14:141-149.
  • Ganapathy N. Sarma, Francis S. Kinderman, Choel Kim, Sventja von Daake, Lirong Chen, Bi-Cheng Wang and Susan S. Taylor. "Structure of D-AKAP2:PKA RI Complex: Insights into AKAP Specificity and Selectivity." Structure. 2009;18(2):155-166.
  • Glen Spraggon, Choel Kim, Xuong Nguyen-Huu, Muh-Ching Yee, Charles Yanofsky, and Stanley E. Mills. "The Structures of Anthranilate Synthase of Serratia marcescens Crystallized in the presence of its substrates, chorismate and glutamine, and a product, glutamate, and (ii) its end product inhibitor L-tryptophan." Proc. Natl. Acad. Sci. 2001;98:6021.
  • GY Huang, JJ Kim, AS Reger, R Lorenz, EW Moon, C Zhao, DE Casteel, D Bertinetti, B Vanschouwen, R Selvaratnam, JW Pflugrath, B Sankaran, G Melacini, FW Herberg and C Kim. "Structural basis for cyclic-nucleotide selectivity and cGMP-selective activation of PKG I.." Structure. 2014;22(1):116-124.
  • GY Huang, OO Gerlits, MP Blakeley, B Sankaran, AY Kovalevsky and C Kim. "Neutron diffraction reveals hydrogen bonds critical for cGMP-selective activation: insights for cGMP-dependent protein kinase agonist design.." Biochemistry. 2014;53(43):6725-6727.
  • DC Guo, E Regalado, DE Casteel, JJ Kim, S Dyack, SG Horne, G Chang, G Jondeau, C Boileau, JS Coselli, Z Li, SM Leal, J Shendure, MJ Rieder, MJ Bamshad, DA Nickerson, C Kim and DM Milewicz. "Recurrent gain-of-function mutation in PRKG1 causes thoracic aortic aneurysms and acute aortic dissections.." 2013;93(2):398-404.