Positions

Assistant Professor
Molecular Virology & Microbiology
Alkek Center for Metagenomics and Microbiome Research
Baylor College of Medicine
Houston, TX, US
Faculty Member
Integrative Molecular and Biomedical Sciences
Baylor College of Medicine
Faculty Member
Quantitative and Computational Biosciences
Baylor College of Medicine
Faculty Member
Developmental Biology
Baylor College of Medicine

Education

PhD from Washington University in St. Louis
Molecular Microbiology and Genomics, Laboratory of Jeffrey Gordon
Post-Doctoral Fellowship at Harvard Medical School / Massachusetts General Hospital
Genetics, Metabolism and Small RNA Biology, Laboratory of Gary Ruvkun

Professional Interests

  • Microbiome programming of host physiology and development
  • Systems biology of host-microbe interactions
  • Host genetic landscapes that determine microbiome form and function
  • High-throughput gnotobiotics in functional phenotyping of human microbiomes

Selected Publications

Memberships

Genetics Society of America
American Society for Microbiology

Funding

Microbiome programming of host physiology - #DP2 DK116645
Grant funding from NIH New Innovator Award
Microbes establish physiologic programs at birth and different microbes during these critical periods influences likelihood of leading a life of health or disease. Despite its importance to all our health, we know very little about the nature of these microbial programming events. We propose to leverage a simple animal system and new innovative methods to define the genetic landscape and response networks of microbial programming at the organismal level in order to identify targets for tailored interventions to support a lifelong healthy balance with our microbes.
Genomic analyses of the natural microbiome of Caenorhabditis elegans
Grant funding from Joint Genome Institute / Department of Energy
Support for full genome sequencing of 92 bacterial isolates of C. elegans natural microbiome.
Junior Faculty Seed Grant
Grant funding from Baylor College of Medicine
Development of a model system to dissect the molecular mechanisms of microbiome impact on infant growth trajectories.
Development of high-throughput genetic strategies to dissect microbiome impact on host physiology
Grant funding from John S. Dunn Collaborative Research Award
Collaboration with Joff Silberg and Grant Hughes to improve throughput of CRISPR targeting systems in multiple hosts.