Texas Children's Hospital Center for Vaccine Development

Texas Children’s Center for Vaccine Development’s (CVD) mission is to develop and advance safe and effective vaccines (and associated technologies) for tropical and emerging infectious diseases, including poverty-related neglected tropical diseases that disproportionately affect the poorest and most vulnerable individuals around the world. 

Over the last 25 years, the CVD has acquired an international reputation for applying a product development partnership (PDP) model, in which nonprofit organizations use industry practices and a collaborative approach to develop, test, advance and ultimately license new global health technologies.

Key Achievements Include:

• Developed a COVID-19 vaccine administered over 100 million times in India and Indonesia.
• Advanced vaccine candidates for emerging coronaviruses, including Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS).
• Created the first vaccine for human hookworm infection, currently in clinical trials.
• Developed the first vaccine for intestinal schistosomiasis, now in clinical trials.
• Pioneered the first vaccine for Chagas disease, also in clinical trials.
• Established a portfolio of early-stage vaccines targeting other major parasitic diseases, including soil-transmitted helminths, onchocerciasis, and leishmaniasis.