Within global health, pediatric emergency medicine stands uniquely poised as the bridge between primary care and definitive tertiary care for children. Therefore clinical, educational, and research initiatives directed at PEM entry points could have a profound impact on reducing child mortality. The section of Pediatric Emergency Medicine at Texas Children’s Hospital is undertaking multiple projects to promote excellence in global health, contributing positive changes in the healthcare outcomes of children. These projects aim to provide comprehensive emergency care for children through the advancement of health in each of several pillars of global health within pediatric emergency medicine: