Department of Medicine

Nephrology Research

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The Section of Nephrology conducts basic and clinical research on kidney function and diseases. Internationally renowned research efforts focus on the cellular and molecular mechanisms of muscle wasting and regeneration in chronic kidney disease, acute renal injury, renal fibrosis, AV fistula dysfunction and hypertension. View a list of our Nephrology research faculty.

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  • Investigate the mechanisms involved in muscle metabolism in chronic kidney disease, renal inflammation which may play a role in the pathogenesis of renal disease and hypertension, and AV fistula dysfunction
  • Provide a coordinated center to facilitate the teaching of fellows entering academic nephrology
  • Fellows entering the Renal Research Training program are mentored under the guidance of the center’s principal investigators
  • Encourage research careers of promising young faculty
  • Provide an avenue to explore new basic and clinical areas that may have clinical research applications
  • Translational and epidemiological studies of chronic kidney disease
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Current Research Projects

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The following is a listing of section faculty research and funding information:

Ahmed Awan, M.D.

  • H31612 - Intermittent fasting from dawn to sunset for prevention of metabolic syndromeinduced cancers
  • 57978-I - Apol1 long-term kidney transplantation outcomes (APOLLO – NIH)

Jizhong Cheng, M.D.

  • Interplay between skeletal muscle catabolism and remodeling of arteriovenous fistulae via YAP1/TAZ signaling; NIH NIDDK (R01)

Kevin Erickson, M.D.

  • Potential Cost Savings from More Widespread Use of Peritoneal Dialysis; Affordability Cures/Blue Cross Blue Shield

Zhaoyong Hu, M.D.

  • Mechanisms of Protein-Energy-Wasting in Chronic Kidney Disease; National Institute of Arthritis and Musculoskeletal and Skin Diseases

Paul Klotman, M.D.

  • Long-Term Consequences of HIV in the Kidney; NIH/NIDDK

Qingtian Li, Ph.D.

  • Megalin, Mitochondrial Intracrine Signaling and the Kidney; VA/Merit

William Mitch, M.D.

  • Protein Metabolism in Experimental Uremia; NIH (R01)
  • Mechanisms Underlying Atrial Fibrillation in Chronic Kidney Disease; NIH (R01) 185

Sankar Navaneethan, M.D.

  • Visceral Adiposity and Physical Function in CKD; NIH/NIDDK (R01)
  • Prevalence, Management, and Outcomes of Iron Deficiency Anemia in CKD; Keryk Biopharmaceuticals

Jenny Pan, M.D.

  • Stanniocalcin-1, Kidney Protection by AMPK; VA/CDA

Rajeev Raghavan, M.D.

  • Study of Sparsentan for patients with Primary Focal Segmental Glomerulosclerosis (DUPLEX); Retrophin

David Sheikh-Hamad, M.D.

  • Megalin, Mitochondrial Intracrine Signaling and the Kidney; VA/Merit

Carl Walther, M.D.

  • Understanding Heart Failure Symptoms in CKD: Distinctive Trajectories, Sex Differences, Cardiorenal Phenotypes, and Prediction (NIH)
  • The kidney in advanced heart failure and durable mechanical circulatory support: phenotypes, prediction, and pathophysiology. (NIH K23)

Wolfgang Winkelmayer, M.D., Sc.D.

  • The Atrial Fibrillation - Factor Identification to Risk Modification Study in CKD/ESRD (NIH R01)
  • QT Prolonging Medications and Sudden Cardiac Death among Individuals on Hemodialysis(NIH R01)
  • United States Renal Data System Coordinating Center (NIH Contract)

Jingyin Yan, M.D., Ph.D.

  • • Comparative Outcomes of Kidney Stone Formers with End-Stage Renal Disease in the United States, Scholarly Time FTE allocation initiative from the Department of Internal Medicine (BCM)
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Clinical Trials

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See what nephrology-related clinical trials are currently being conducted at Baylor College of Medicine.

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