research › ... › publications
… L , Li JJ, Li W. The concurrence of DNA methylation and demethylation is associated with transcription regulation. Nature Communications. 2021 Sept 6; 12(1):5285. PMID: 34489442 … Jun 17: 151455. Pubmed PMID: 34246487 Alves da Silva AV, de Castro Oliveira SB, Di Rienzi SC, Brown-Steinke K, Dehan …
news › serotonin-2c-receptor-associated-with-obesity-and-maladaptive-behavior
… associated with obesity and maladaptive behavior. The evidence shows that rare mutations in the gene for the serotonin 2C receptor play a role in the development of obesity and dysfunctional behaviors in humans … messages from one part of the brain to another. Serotonin communicates the message by binding to brain cells carrying …
news › kipa-potentially-predicts-chemotherapy-response-in-triple-negative-breast-cancer
… College of Medicine and collaborating institutions are developing a strategy to predict the response of triple … an individual basis. The study appears in Cancer Research Communications , a journal of the American Association for … Each kinase binds to its specific inhibitor, effectively separating it from other cell components, though some kinases …
news › baylor-researchers-highlight-benefits-of-sharing-human-brain-data
… In recent years, the scientific community has seen a push for more findable, accessible, … a team of researchers, led by coauthors Dr. Vasiliki Rahimzadeh , assistant professor at the Center for Medical Ethics … through broad and secure data sharing,” explains Rahimzadeh. “While there has been a lot of attention paid to …
news › researchers-create-ai-model-to-understand-how-brain-activity-relates-to-illness
… artificial intelligence (AI) to create a foundational model for brain activity. Brain Language Model (BrainLM) was developed to model the brain in silico and … people started using machine learning to capture the brain complexity and how it relates it to specific illnesses, but …
news › for-media › clinical-chairs
… James Anton, M.D.,  was named chair of the Department of Anesthesiology on Nov. 1, 2021. Dr. Anton has served as the Interim Co-Chair of the department since May 2019 and serves as Chief of … degree from Georgetown University School of Medicine and completed his residency training at Brigham and Women’s …
research › ... › publications
… phenotypes in a myotonic dystrophy type 1 heart mouse model. J. Clin. Invest. (In Press). Nitschke, L., Hu, R-C, … Nitschke, L. & Cooper, T. A. (2024) Combinatorial effects of ion channel mis-splicing as a cause … (2005) Co-localization of muscleblind with RNA foci is separable from mis-regulation of alternative splicing in …
research › ... › research-areas
… to explore the pathogenesis of polyglutamine neurodegenerative diseases, the function of Math1 in neurodevelopment, and how MECP2 mutations cause postnatal neurodevelopmental disorders. … affects. Lastly, we recently found that the Ataxin-1 paralog (Ataxin-1 like) can suppress neurodegeneration in …
news › novel-brain-stimulation-approach-treats-severe-depression
… But he wasn’t in distress; in fact, he says, “It was suddenly like I was back online.” John, who suffers from treatment resistant depression (TRD), is the first person to participate in a … suicide in a past depressive state and ending up in a coma for a short time, so I knew this was something I had to …
news › 2024-michael-e-debakey-excellence-in-research-awards
… This year’s Michael E. DeBakey Excellence in Research Awards were given to six … C. Magee and Dr. Christine Beeton. The award ceremony included a recorded message from Dr. Paul Klotman, Baylor … executive dean, congratulating the group. He added their accomplishments exemplify the outstanding work across all …
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