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healthcare › ... › huntingtons-disease
… Huntington's disease (HD) is a hereditary neurodegenerative disorder caused by a mutation in the gene … psychiatric symptoms include irritability, depression, paranoia, and erratic behavior. Patients may also exhibit manic and obsessive-compulsive states. Other symptoms may include anxiety, …
research › ... › publications
… Select Recent Publications Bolded names denote members of the Wehrens lab Keefe JA , … Tardif JC, Wehrens XHT , Nattel S, Reilly S. Calcitonin paracrine signaling controls heart fibrogenesis and … Ackerman MJ, Wehrens XH . Disrupted junctional membrane complexes and hyperactive ryanodine receptors after acute …
departments › ... › fellows
… : California North State University College of Medicine Residency : Baylor College of Medicine-San Antonio, Texas … Interests : Classic film, trivia, my tripod cat with complex sinus disease, San Antonio's expanding and diverse … CHRISTUS Children's? I was drawn to this program for its wide breadth of subspecialty experiences within the field of …
news › pfa-ependymoma-brain-tumors-display-unique-3d-genome-features-that-could-be-exploited-therapeutically
… Researchers have identified unique 3-dimensional features called TULIPs in the … and collaborating institutions, could lead to the development of new treatments. “PFA ependymomas are lethal. … of entire genomes of pediatric PFA ependymomas and compared them with those of different tumor types and …
about-us › ... › lighting-systems
… In large scale operations it is important that all energy delivered to a site be used efficiently as possible. The … measure of power conversion efficiency within a facility is described or defined by the "Power Factor" (PF). An electric … power consumed is converted into rotational energy. Power companies have to transport more power to consumers who have …
healthcare › ... › pericardiectomy
… A small amount of fluid will ensure the layers stay separate and have no friction between them. Pericarditis can … on its own or with simple treatment. If treatment is needed, it can include medication and rarely will include surgery. … The root cause of pericarditis is sometimes hard to determine, or deemed to be unknown. Possible causes of …
research › ... › stop-smoking
… with 32 percent of women with disabilities smoking compared to 23 percent of adults in general. An analysis of … While smoking is a substantial risk factor for disease and death for anyone, it may impart even higher risks for people … of time it takes for a wound to heal Poor post-operative outcome in spinal surgeries and joint replacement procedures …
research › ... › projects
… brain KCNQ2 and KCNQ3 potassium channels were bound in a detergent-insoluble protein complex. With collaborators at Penn, he found this protein … complex was located at axonal initial segments and nodes of Ranvier. The initial segments (highlighted in figure … NaV and KCNQ2 co-localization depends on similar ankyrin-G binding "anchor" motifs. …
research › ... › research-areas
… our laboratory is the transcriptional mechanisms governing developmental gliogenesis. As a postdoc, Ben discovered that … factor NFIA regulates the initiation of gliogenesis ( Deneen, et al. Neuron 2006 ) and our lab found that Sox9 and NFIA comprise a transcriptional cascade essential for the …
news › solving-the-cnl6-mystery-in-batten-disease
… Collectively, they are the most prevalent cause of neurodegenerative disease in children, affecting 1 in 12,500 live … that break down waste products into its constituent components that the cell can recycle or discard. In Batten … lysosomal enzymes, are made. The endoplasmic reticulum is separate from the lysosomes. So, how do defects in a protein …
