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news › maternal-diet-during-lactation-affects-milk-bacteria
… “This was particularly exciting, since HMOs are basically inert substances to a mother or her baby. However, they … the team of researchers supplied breastfeeding mothers with all their meals in a controlled setting at the USDA … and energy sources in the diets we provided preferentially altered the milk concentrations of HMOs, and this was …
news › getting-ahead-of-the-infection-phages-anticipate-bacterias-location
… virus that infects and destroys bacteria, that can specifically locate in the same place the bacteria live in the … and microbiology at Baylor. “We discovered a novel phage called ES17 that binds to mucins, and this property seemed to … discovered that phage ES17 binds to particular molecules called heparan sulfate which can be found not only in mucins, …
news › aspirin-reduces-preeclampsia-risk-affecting-the-gestation-metabolic-clock
… of maternal and perinatal morbidity and mortality. Globally, it is associated with 76,000 maternal and 500,000 … could reduce the rates of preterm preeclampsia and all preeclampsia by 60% and 30%, respectively. “Our work has … age. Changes during advancement of gestation were also partially reversed by aspirin in one-fourth of the …
news › bcm-partners-with-largest-autism-study-celebrating-five-years-of-genetic-research
… autism but it also is a powerful resource that will shape all kinds of autism research for decades to come. This is … Because it widely varies between individuals, it is challenging to study ASD holistically. While past decades have seen significant advances in …
news › circadian-clock-in-heart-failure
… Disrupting circadian rhythms, which change naturally on a 24-hour cycle, has been implicated in heart … the metabolism of the heart by knocking it out specifically in mouse cardiomyocytes,” said co-corresponding author … insulin resistance. “The high-fat/high-sucrose diet partially alleviated the cardiac defects, but the high-fat diet …
news › novel-approach-identifies-highly-specific-anti-cancer-compounds
… proteins involved in cancer. The compounds, called BET BD1-inhibitors, are a starting point in the development of potentially more effective anti-cancer drugs with less side … faster and more cost-effective drug discovery tool called DNA-Encoded Chemistry Technology, which enables us to …
news › oops-after-ten-years-and-1000-studies-epigeneticists-uncover-trouble-in-their-tool-box
… tool that has been the workhorse for these studies is actually not appropriate for population epigenetics. “Many … likewise has a unique level of molecular individuality called its epigenome,” said co-corresponding author Dr. … study DNA methylation, which occurs at specific locations called CpG sites. The standard tool for population studies of …
research › ... › publications
… All models available on our NIH 3D Repository Page … Chlouber, B. and Dzakovich, M.P. One Gallon Pot Six Seed Punch. 2023. NIH 3D. … . Chlouber, B. and Dzakovich, M.P. 2022. Thingiverse. One Gallon Pot Six Seed Punch. Chlouber, B. and Dzakovich, M.P. … profiles of greenhouse tomatoes using environmentally relevant doses of ultraviolet radiation . Ag. & Food …
news › protein-eif4a-emerges-as-a-potential-achilles-heel-for-triple-negative-breast-cancer
… poor prognosis and limited therapeutic targets, has been challenging. Responding to this need for better treatments, … TNBC animal models, targeting protein eIF4A with the small molecule drug Zotatifin not only suppresses tumor cell … the corresponding author of the work. “TNBC tumors are typically ‘cold tumors,’ meaning they have more immune cells that …
news › common-olympic-injuries
… The 2024 Olympic Games are top of mind for people globally. While the athletes make their sports look effortless, … Basketball … Basketball is high-impact, lower-extremity-related sport often … the ankle stretch beyond their limits or tear, typically during sudden changes in direction or improper …
