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news › researchers-uncover-the-first-steps-driving-antibiotic-resistance
… Yin Zhai, postdoctoral associate in the Rosenberg lab. “Usually, cells regulate their activities by producing specific … a major role in regulating DNA repair,” Zhai said. “A small molecule called nucleotide ppGpp, which is present in bacteria exposed …
news › study-helps-explain-severe-graft-versus-host-disease-and-potential-solution
… follows immune-mediated intestinal damage. Pharmacologically reducing intestinal oxygen levels alleviated the microbial imbalance and reduced the severity … other inflammatory intestinal conditions.” GVHD is a potentially life-threatening complication of bone marrow …
news › car-nkt-cell-therapy-shows-promising-results-against-neuroblastoma-in-phase-1-clinical-trial
… the team have shown that NKT cells can localize to tumor sites in pre-clinical models. This trial has validated those …
research › ... › assign-anxiety-ratings
… your possible activities onto post-its, notecards, or small slips of paper for this process, so they are easy to … report their level of anxiety for a given situation – especially if they have to guess without actually being in the situation! If your child has been able to …
news › baylor-researchers-highlight-benefits-of-sharing-human-brain-data
… community must feel incentivized to share data in a maximally useful way rather than doing the minimum required to … groups, but to also support replicability studies that overall enhance scientific rigor. “The benefits to users include … reasonably be expected to produce. This makes sharing data all the more important. Additionally, sharing data has had …
research › ... › research-projects
… resident SSCs. Our lab has previously identified functionally distinct P-SSCs using a combination of Mx1 and SMA to … resident P-SSCs in adult periosteum. These P-SSCS specifically express the CCL5 receptor CCR5 and CCL5 induces in vivo … Reconstruction of bone defects is important but challenging in patients with Osteogenesis Imperfecta (OI) or …
research › ... › projects
… ritualistic behaviors), and exemplifies a pathologically avoidant phenotype where greater degrees of avoidance … OCD by providing the “boost” in pro-approach behavior that allows individuals to overcome their pathological fear-based … axes underlying the pathophysiology of OCD. Our overall goal is to develop a mechanistic understanding of DBS …
news › brain-stars-hold-our-memories
… have been explained by the activity of brain cells called neurons that respond to learning events and control memory recall. The Baylor team expanded this theory by showing that non-neuronal cell types in the brain called astrocytes – star-shaped cells – also store memories …
news › dont-fall-for-allergies-this-season
… It’s finally fall, and as the crisp weather rolls in, many are rushing to get outside. As allergens fill the air, people should take precaution when … time outdoors this season. A Baylor College of Medicine allergist and pulmonologist provides tips to maintain …
Compound d16 reduces tumor growth and overcomes therapeutic resistance in mutant p53-bearing cancers
news › compound-d16-reduces-tumor-growth-and-overcomes-therapeutic-resistance-in-mutant-p53-bearing-cancers
… Baylor College of Medicine have developed a new compound called d16 that can reduce tumor growth and overcome … in many human cancers is mutations in p53, a gene that normally provides one of the most powerful shields against tumor … promote cancer growth has been difficult. “One of the challenges has been to develop drugs that act on mutant p53 …