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news › getting-ahead-of-the-infection-phages-anticipate-bacterias-location
… of the bacteria. This strategy has the potential of becoming a game changer in the fight against … in mucin-rich environments, such as the gut.” Further studies looked closer at this novel phage-mucin interaction. … targeting will be the way smart drugs work in the future. Drugs won’t be just distributed all through the body …
news › aspirin-reduces-preeclampsia-risk-affecting-the-gestation-metabolic-clock
… demonstrated that the preeclamptic or non-preeclamptic outcome in response to aspirin treatment was significantly … of maternal and perinatal morbidity and mortality. Globally, it is associated with 76,000 maternal and 500,000 … the importance of both basic and translational studies in the assessment of therapeutic interventions,” said …
news › bcm-partners-with-largest-autism-study-celebrating-five-years-of-genetic-research
… that will shape all kinds of autism research for decades to come. This is why it is so important that families join now, … part of what we are learning about autism, now and in the future." As a SPARK recruiter, Baylor is helping drive … from scientists to participate in new autism research studies through SPARK Research Match, enabling research on …
news › circadian-clock-in-heart-failure
… investigated the function of the protein Rev-erbα/β, a key component of the circadian clock, on heart disease … dilated cardiomyopathy and lethal heart failure. “We studied how the Rev-erbα/β gene influenced the metabolism of … just in this study, but for many other medications. “Of the top 100 most prescribed drugs in the U.S., at least half of …
news › novel-approach-identifies-highly-specific-anti-cancer-compounds
… Children’s Hospital have identified potent, highly specific compounds that interfere with bromodomain (BD)-containing … proteins involved in cancer. The compounds, called BET BD1-inhibitors, are a starting point in the … Center at Baylor. The researchers conducted 3D molecular studies to determine the precise location on the BD1 protein to …
news › oops-after-ten-years-and-1000-studies-epigeneticists-uncover-trouble-in-their-tool-box
… began conducting large genome-wide association studies to identify genomic regions linked to human disease. In … researchers at Baylor College of Medicine reveals that the commercial tool that has been the workhorse for these studies is actually not appropriate for population epigenetics. “Many …
research › ... › publications
… All models available on our NIH 3D Repository Page … M.P., Le, E.A., Tak, A.L., Chacko, S.K. (2024). A Comprehensive UHPLC-MS/MS and Extraction Method for Spinach … . Ag. And Food Chem. 68(18):5241-5248. doi: 10.1021/acs.jafc.0c01681 Dzakovich, M.P., Gas-Pascual, E., Orchard, C.J., …
news › protein-eif4a-emerges-as-a-potential-achilles-heel-for-triple-negative-breast-cancer
… in TNBC that could lead to novel therapies and improved outcomes for this devastating condition. The team reports in … promising results,” Zhao said. “We are hoping that our studies could help inform future clinical trials and positively impact the treatment …
news › common-olympic-injuries
… The 2024 Olympic Games are top of mind for people globally. While the athletes make their sports look effortless, … A Baylor College of Medicine orthopedic surgeon details common injuries among fan-favorite Olympic sports. … …
news › dr-hugo-bellen-named-recipient-of-the-2024-gruber-genetics-prize
… to how disruptions in these pathways lead to rare and common brain disorders and, finally, to finding new ways to diagnose and treat these … how the peripheral nervous system develops and how neurons communicate with one another. He elucidated the role of …
