news › oops-after-ten-years-and-1000-studies-epigeneticists-uncover-trouble-in-their-tool-box
… began conducting large genome-wide association studies to identify genomic regions linked to human disease. In … modifications to test associations with disease. Today more than 1,000 such epigenome-wide association studies … researchers at Baylor College of Medicine reveals that the commercial tool that has been the workhorse for these …
news › getting-ahead-of-the-infection-phages-anticipate-bacterias-location
… of the bacteria. This strategy has the potential of becoming a game changer in the fight against … in mucin-rich environments, such as the gut.” Further studies looked closer at this novel phage-mucin interaction. … Fund at Baylor St. Luke’s Medical Center, the Mike Hogg Foundation and Baylor College of Medicine Seed Fund. …
news › circadian-clock-in-heart-failure
… investigated the function of the protein Rev-erbα/β, a key component of the circadian clock, on heart disease … as a source of energy during the animal’s resting time, daytime for mice. Removing Rev-erbα/β disrupts this rhythm, … dilated cardiomyopathy and lethal heart failure. “We studied how the Rev-erbα/β gene influenced the metabolism of …
research › ... › publications
… M.P. 6 x 4 PoxyGrid 15 mL Conical Tube Metal Rack Adapter - Orbital Shaker to Vortexer Conversion Device. NIH … 2022. Thingiverse. 15 mL Conical Tube Rack and Shaking Adapter . Chlouber, B. and Dzakovich, M.P. 2022. Thingiverse. … Dzakovich, M.P., Le, E.A., Tak, A.L., Chacko, S.K. (2024). A Comprehensive UHPLC-MS/MS and Extraction Method for Spinach …
news › protein-eif4a-emerges-as-a-potential-achilles-heel-for-triple-negative-breast-cancer
… in TNBC that could lead to novel therapies and improved outcomes for this devastating condition. The team reports in … chemotherapy and immunotherapy. “We observed increased DNA damage and cell death after three days of a combination … promising results,” Zhao said. “We are hoping that our studies could help inform future clinical trials and positively …
news › dr-hugo-bellen-named-recipient-of-the-2024-gruber-genetics-prize
… The Gruber Foundation at Yale University has named eminent geneticist, Dr. … of Medicine and principal investigator at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at … to how disruptions in these pathways lead to rare and common brain disorders and, finally, to finding new ways to …
research › ... › astro-accommodation-of-anxiety-behaviors
… help them with their quick fixes. This is what we call “accommodation”. Sometimes, avoidance behaviors and quick fixes can become so integrated into your family’s lives that they are … Now it’s your turn! Fill out this Accommodation Worksheet to track the things you do to …
research › ... › lab-members
… Southwestern’s M.D./Ph.D. graduate program. Under the guidance of scientific mentor, Dr. Andrew Zinn, Dr. Holder … demonstrate that over-expression of SIM 1 protects against diet-induced obesity via gene-regulated actions upon the … rodent behaviors to model human neurologic diseases. He accomplished this by performing research relating to the role …
research › ... › accommodation-of-anxiety-behaviors
… help them with their quick fixes. This is what we call “accommodation”. Sometimes, avoidance behaviors and quick fixes can become so integrated into your family’s lives that they are … Now it’s your turn! Fill out this Accommodation Worksheet to track the things you do to …
news › nih-awards-more-than-15-million-to-fund-two-rare-diseases-consortia
… longitudinal cohort of OI patients in the world to collect data on skeletal features, quality of life and psychosocial … study. Researchers also established 10 pilot studies addressing patient needs and published nearly 50 … BBDC will focus on three projects. First, researchers will complete the longitudinal study with six years of follow up …
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