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… inhibitors are an emerging and often very successful class of cancer drugs that target chromatin modifying … of these inhibitors, including some novel inhibitors developed here at Baylor College of Medicine, to understand … proteoform level. Our focus is to understand how specific combinations of PTMs respond differentially to these …
research › ... › research-areas
… Research in the Britton lab is focused on four major areas: Limosilactobacillus Reuteri as a Key Therapeutic Bacterial … Between Intestinal Hormones and the Microbiota Synthetic Biology for Diagnosing and Treating Disease Microbial Ecology … Britton Lab Research Areas …
research › ... › research-projects
… These two agouti viable yellow ( A vy ) heterozygous littermates are genetically identical. Their physical differences are due to a naturally-occurring difference in DNA methylation at the A vy metastable epiallele. We are working to … Identification and characterization of human metastable …
research › ... › research
… Stem cell aging and cellular senescence are important processes that contribute to the aging pathology and development of cancer. As a complement to our yeast replicative aging model, we are … phenomena. It is very clear now epigenetics represents a complex regulation network on top of the genetic code. In …
research › ... › student-information
… Xander Wehrens, M.D., Ph.D. is a Professor of Integrative Physiology and Medicine (in Cardiology), with secondary … and graduate students, clinical and research fellows in his laboratory. Dr. Wehrens accepts trainees from the programs … Clinical Fellows and Junior Faculty …
research › ... › lab-members
… The Li lab periodically has vacancies for postdoctoral fellows. Applicants should have a Ph.D. or M.D. degree, with strong experience in molecular biology. Please … Yi Li Lab Members …
research › ... › publications
… in HER2-positive breast cancer treated with dual HER2 blockade A combinatorial biomarker predicts pathologic complete response to neoadjuvant lapatinib and trastuzumab without chemotherapy in patients … Schiff-Osborne Lab Publications …