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… Paligenosis is how differentiated cells return to the cell cycle. It is a cellular program that is evolutionarily conserved across organs and species, similar to how … In tissues with constitutively dividing undifferentiated stem cells (like the epithelium of the GI tract), …
research › ... › publicatations
… 2019 Oct 24. PubMed PMID: 31607221; PubMed Central PMCID: PMC7939568. Furuta Y, Pena-Ramos O, Li Z, … diphosphate kinase NDK-1/NME1 promotes phagocytosis in concert with DYN-1/Dynamin. FASEB J. 2019 … 2015 Jun. PubMed PMID: 26061275; PubMed Central PMCID: PMC4464654. Shen Q, He B, Lu …
research › ... › publications
… JH, Gupta R, Reyes JM, Gundry MC, Medrano G, Guzman A, Ajuilar R, Conneely SE, Song T, Johnson C, Cristobal CDD, Kurtz K, Brunetti L, Goodell MA, … . Modeling IKZF1 lesions in B-ALL reveals distinct chemosensitivity patterns and potential therapeutic … Doi: 10.1182/bloodadvances.2020002408. PMID: 3442683. Conneely SE, McAtee CL, Gupta R, Lubega J, Scheurer …
research › ... › news
… Both Drs. Annita Achilleos and Elda Reuda have received tenure-track faculty jobs! Annita will be an Assistant … Congrats to Tiffany Chern for receiving a travel award to attend the Cold Spring Harbor Laboratory Mouse Development, … Tiffany was also a finalist in the Wiki Science Image Competition! Dr. Annita Achilleos and Tiffany Chern …
research › faculty-labs › huda-zoghbi-lab
… The laboratory uses genetic, biochemical, and cell biological approaches to explore the pathogenesis of polyglutamine neurodegenerative diseases and Rett syndrome, and to study genes … Dr. Huda Y. Zoghbi is a professor in the Departments of Pediatrics, Molecular and Human Genetics, Neurology …
research › faculty-labs › james-versalovic-lab
… Versalovic Lab Members … team in the James Versalovic Laboratory explores how beneficial microbes can promote health, relieve disease, and … bowel syndrome. Probiotic beneficial bacteria derived from commensal microbes are being studied as natural modulators … be applied to the discovery of novel probiotics for the control of mucosal inflammation and immune responses to …
research › faculty-labs › melanie-samuel-lab
… The Samuel lab seeks to uncover the molecular signals that … health and disease remain largely unknown. Research in the Samuel lab seeks to decode these molecular languages by … See information about the areas of research in the Samuel Lab. … The Samuel Lab believes in helping humanity through engaging the …
research › faculty-labs › michael-ittmann-lab
… A group photo of the Michael Ittmann Lab members. … Research in the Michael Ittman Laboratory is focused on the molecular genetics of human prostate cancer and the pathobiology of benign prostatic hyperplasia. In particular, we are … and Northern blotting to determine quantitatively the content of FGFs in prostate cancer, the tissues (epithelial or …
research › faculty-labs › michael-lewis-lab
… Research in the Lewis lab is focused on the genetic regulation of mammary gland development and early-stage breast cancer. … cancer is widely recognized as a key to effective treatment, yet very little is known about the earliest stages of … normally throughout the life of a woman. Without a more complete understanding of the normal mammary gland, early …
research › faculty-labs › paul-pfaffinger-lab
… Dr. Pfaffinger leads the research efforts in this lab. … Drs. Pfaffinger and Jerng consulting on an experiment. … Understanding the regulation of ion channels and their role in native neurons is a major focus of my laboratory. Our work is ultimately tied to our interest in …