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research › faculty-labs › perumal-thiagarajan-lab
… The major emphasis of the Thiagarajan Lab is to elucidate the mechanism of the hypercoagulable … systemic lupus erythematosus and allied autoimmune disorder have antibodies that react with anionic phospholipid … The immunological specificity of these antibodies is complex and it ranges from phospholipid binding proteins, a …
research › faculty-labs › robia-pautler-lab
… The Pautler Lab develops and applies methodologies that permit high-resolution images of the structure … research efforts build upon the new technique that she developed known as Manganese Enhanced MRI (MEMRI) neuronal … is also paramagnetic, rendering it MRI detectable in spin-lattice (T1)-weighted MRI images. It is therefore possible …
research › faculty-labs › edward-cooper-lab
… The Cooper Lab is focused … on understanding and developing new treatments for forms of … infants, children, and adults, mood disorder that often accompanies epilepsy, and related brain disease. These are complex developmental … in technique, systems, and scale, and include basic molecular, explicitly translational, and clinical research, as …
research › faculty-labs › frank-horrigan-lab
… into electrochemical signals by opening and closing to regulate membrane permeability. In this way channels mediate … function of nerve, muscle, and other cell types. Thus an understanding of ion channel gating has broad consequences for … However, the mechanisms by which sensors and gates communicate represent a key aspect of channel gating that …
research › faculty-labs › monica-pillon-lab
… The Pillon Lab aims to uncover the structure, function, and regulation of RNA processing and decay factors associated with human disease. To define the … basis for gene dysregulation in disease states, we combine hybrid structural biology, enzymology, molecular …
research › faculty-labs › akash-patel-lab
… sites nationally to first sequence the human genome. Dr. Patel’s laboratory works in collaboration with the … novel therapies to treat these devastating tumors. Dr. Patel has a research laboratory dedicated to understanding … Akash Patel Lab …
research › faculty-labs › martin-matzuk-lab
… from the April 15, 2023 Thirty Years of Reproductive Biology Research – A BCM Symposium Honoring Professor Martin M. … Over the last 25 years, our research program has focused on the identification and functional analysis of genes and pathways … About the Lab … Martin Matzuk Lab …
research › faculty-labs › ming-zhou-lab
… chemical and physical principles in membrane proteins: How substrates are recognized; what structural changes are required for substrate binding and translocation; and how substrates are translocated across the membrane or …
research › faculty-labs › paul-klotman-laboratory
… The Paul Klotman laboratory studies HIV-associated nephropathy … a reservoir for replicating virus distinct from peripheral blood. Additionally, we have elucidated how HIV disrupts … Paul Klotman Laboratory …