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news › integrative-exome-sequencing-and-machine-learning-identify-new-genes-contributing-to-systemic-sclerosis-risk
… Systemic sclerosis (SSc) is a severe autoimmune disease with complex genetic causes. Some genetic contributors have been … College of Medicine and collaborating institutions used complementary approaches that integrate exome sequencing and … mechanisms in SSc. Previous genome-wide association studies (GWAS) that analyzed the frequency of common genetic …
news › brain-stars-hold-the-power-to-preserve-cognitive-function-in-model-of-alzheimers-disease
… for normal brain function, including facilitating brain communications and memory storage. As the brain ages, … Alzheimer’s disease, focusing on Sox9, as this protein is a top regulator of multiple genes in aging astrocytes. “We manipulated the …
news › researchers-uncover-risk-of-shoulder-injury-during-and-after-spaceflight
… of orthopedic surgeons at Baylor College of Medicine studied the risk of shoulder injury during and post spaceflight … focus on upper extremity and shoulder injuries or complaints. “The main finding of the study was that … in space,” he said. The team hopes to conduct further studies with astronauts in real time to prevent further …
news › fossils-of-ancient-chromosomes-discovered
… ancient chromosomes in the remains of a woolly mammoth that died 52,000 years ago. The fossils preserve the structure of … “By comparing ancient DNA molecules to the DNA sequences of … active. This is because of a phenomenon called chromosome compartmentalization – the fact that active and inactive DNA …
departments › ... › systematic-reviews-workshop
… Systematic reviews are comprehensive, structured reviews of the evidence on … a focused question around a clinical topic Perform a comprehensive literature search Critically appraise published studies, grade the evidence, and pool the quantitative results … ‘Poll everywhere’ app will be used as needed to gauge audience perceptions and knowledge Systematic reviews comprise …
research › ... › finding-a-health-care-provider
… consider giving total control of our life savings over to a complete stranger. Yet this is how most of us choose our … and entrust them with the future well being of our bodies. We permit doctors to make decisions about the most … and the power of decision-making given to one individual so completely and without question. So how do you choose the …
news › graduates-encouraged-to-be-ready-for-unexpected-forks-in-the-road-that-can-lead-to-success
… take the unexpected forks in the road that will inevitably come along, because they can turn into opportunity. Perhaps … in Houston and, now, a global pandemic. The 2021 Commencement Ceremony was held Thursday, May 27, at the … to grow human T cells. He eventually applied these HIV studies to cancer patients and found that his lab had a major …
news › novel-technology-makes-studying-gene-function-easier-faster
… new technology as well as examples of its applications. A companion paper in STAR Protocols shows how to set up, … improved the screening process,” said Dr. Herman A. Dierick , associate professor of molecular and human … and the National Institutes of Health grants 1R21HG006726, 1R21GM110190,1R21OD022981, R01GM109938, and R01MH107474. …
news › genomic-alterations-in-advanced-cancers-reveal-interactions-with-therapy
… and the possibility of preventing or minimizing outcomes with treatments. “Treatment resistance is a big … cancer types analyzed, the team identified more than 300 top genes with altered expression. “Not all of these genes … Genome Sciences Centre. “To date, most tumor profiling studies only have sequenced a small proportion of the genome, …
news › a-novel-switch-to-turn-genes-on-off-promising-step-toward-safer-gene-therapy
… this technology and now they have found a solution to overcome the main obstacles in its clinical use. “The solution … engineered to contain an extra polyA signal, akin to a “stop sign” that genes naturally use to mark the end of a … A patient has received gene therapy that provides a gene to compensate for a malfunctioning gene that causes a medical …
