William
Middle Name
Wai-Lun
Wong, Ph.D.
Middle Name
Wai-Lun
Picture
Positions
- Professor
-
Pediatrics-Nutrition
Baylor College of Medicine
Houston, TX US
Education
- Advanced Training from Texas A&M University
- 01/1976 - College Station, TX United States
- Ph.D. from Texas A&M University
- 01/1976 - College Station, TX United States
- M.S. from Texas A&M University
- 01/1974 - College Station, TX United States
- B.S. from Texas Lutheran College
- 01/1972 - Seguin, TX United States
Honors & Awards
- Young Investigator Award
- Award given to a highly productive junior faculty
- USDA/ARS Children's Nutrition Research Center (03/1985)
- Community Leadership Award
- Recognition of leadership in a community-based healthy living promotion program among minority children
- President's Council on Fitness, Sports and Nutrition (05/2012)
- Educator Outstanding Service Award
- Recognition for promoting awareness among the management and staff of the Houston Parks & Recreation Department on the epidemic of childhood obesity among minority children.
- Texas Recreation & Park Society (03/2013)
Professional Statement
My main research involves studies of dietary supplementation to prevent chronic diseases, intervention of childhood obesity, and energy metabolism under healthy conditions and diseased states.Websites
Selected Publications
- Wong WW, Clarke LL "A hydrogen gas-water equilibration method produces accurate and precise stable hydrogen isotope ratio measurements in nutrition studies.." J. Nutr.. 2012 November ; 142 (11): 2057-62. Pubmed PMID: 23014490
- Wong WW, Hachey DL, Clarke LL, Zhang S, Llaurador M, Pond WG "An improved HPLC method to purify erythrocyte cholesterol for estimation of in vivo cholesterol synthesis using the deuterium method.." Appl Radiat Isot. 1994 April ; 45 (4): 529-33. Pubmed PMID: 8186774
- Wong WW, Clarke LL, Llaurador M, Klein PD "A new zinc product for the reduction of water in physiological fluids to hydrogen gas for 2H/1H isotope ratio measurements.." Eur J Clin Nutr. 1992 January ; 46 (1): 69-71. Pubmed PMID: 1313759
- Wong WW, Barlow SE, Mikhail C, Wilson TA, Hernandez PM, Shypailo RJ, Abrams SH "A Residential Summer Camp Can Reduce Body Fat and Improve Health-related Quality of Life in Obese Children.." J. Pediatr. Gastroenterol. Nutr.. 2013 January ; 56 (1): 83-5. Pubmed PMID: 22995865
- Wong WW, Abrams SH, Mikhail C, Terrazas NL, Wilson TA, Arceo D, Mrowczynski PK, King KL, Stansel AD, Albright AN, Barlow SE, Brown KO, Brown JD, Klish WJ "An innovative summer camp program improves weight and self-esteem in obese children.." J. Pediatr. Gastroenterol. Nutr.. 2009 October ; 49 (4): 493-7. Pubmed PMID: 19590448
- Butte NF, Hopkinson JM, Wong WW, Smith EO, Ellis KJ "Body composition during the first 2 years of life: an updated reference.." Pediatr. Res.. 2000 May ; 47 (5): 578-85. Pubmed PMID: 10813580
- Ellis KJ, Abrams SA, Wong WW "Body composition of a young, multiethnic female population.." Am. J. Clin. Nutr.. 1997 March ; 65 (3): 724-31. Pubmed PMID: 9062521
- Wong WW, Butte NF, Smith EO, Garza C, Klein PD "Body composition of lactating women determined by anthropometry and deuterium dilution.." Br. J. Nutr.. 1989 January ; 61 (1): 25-33. Pubmed PMID: 2647135
- Ellis KJ, Abrams SA, Wong WW "Body composition reference data for a young multiethnic female population.." Appl Radiat Isot. 49 (41400): 587-8. Pubmed PMID: 9569548
- Hopkinson JM, Butte NF, Ellis KJ, Wong WW, Puyau MR, Smith EO "Body fat estimation in late pregnancy and early postpartum: comparison of two-, three-, and four-component models.." Am. J. Clin. Nutr.. 1997 February ; 65 (2): 432-8. Pubmed PMID: 9022527
- Wong WW, Cochran WJ, Klish WJ, Smith EO, Lee LS, Fiorotto ML, Klein PD "Body fat in normal adults estimated by oxygen-18- and deuterium-dilution and by anthropometry: a comparison.." Eur J Clin Nutr. 1988 March ; 42 (3): 233-42. Pubmed PMID: 3289914
- Ellis KJ, Yao M, Shypailo RJ, Urlando A, Wong WW, Heird WC "Body-composition assessment in infancy: air-displacement plethysmography compared with a reference 4-compartment model.." Am. J. Clin. Nutr.. 2007 January ; 85 (1): 90-5. Pubmed PMID: 17209182
- Ellis KJ, Shypailo RJ, Wong WW, Abrams SA "Bone mineral mass in overweight and obese children: diminished or enhanced?." Acta Diabetol. 2003 October ; 40 : S274-7. Pubmed PMID: 14618492
- Butte NF, Hopkinson JM, Ellis KJ, Wong WW, Smith EO "Changes in fat-free mass and fat mass in postpartum women: a comparison of body composition models.." Int. J. Obes. Relat. Metab. Disord.. 1997 October ; 21 (10): 874-80. Pubmed PMID: 9347405
- Wong WW, Smith EO, Stuff JE, Hachey DL, Heird WC, Pownell HJ "Cholesterol-lowering effect of soy protein in normocholesterolemic and hypercholesterolemic men.." Am. J. Clin. Nutr.. 1998 December ; 68 (6): 1385S-1389S. Pubmed PMID: 9848504
- Butte NF, Wong WW, Garza C "Energy cost of growth during infancy.." Proc Nutr Soc. 1989 July ; 48 (2): 303-12. Pubmed PMID: 2678126
- Treuth MS, Butte NF, Wong WW "Effects of familial predisposition to obesity on energy expenditure in multiethnic prepubertal girls.." Am. J. Clin. Nutr.. 2000 April ; 71 (4): 893-900. Pubmed PMID: 10731494
- Wong WW, Taylor AA, Smith EO, Barnes S, Hachey DL "Effect of soy isoflavone supplementation on nitric oxide metabolism and blood pressure in menopausal women.." Am. J. Clin. Nutr.. 2012 June ; 95 (6): 1487-94. Pubmed PMID: 22552034
- Pond WG, Insull W, Mersmann HJ, Wong WW, Harris KB, Cross HR, Smith EO, Heath JP, Kömüves LG "Effect of dietary fat and cholesterol level on growing pigs selected for three generations for high or low serum cholesterol at age 56 days.." J. Anim. Sci.. 1992 August ; 70 (8): 2462-70. Pubmed PMID: 1506308
- Wong WW, Hachey DL, Insull W, Opekun AR, Klein PD "Effect of dietary cholesterol on cholesterol synthesis in breast-fed and formula-fed infants.." J. Lipid Res.. 1993 August ; 34 (8): 1403-11. Pubmed PMID: 8409771
- Schoknecht PA, Ebner S, Pond WG, Zhang S, McWhinney V, Wong WW, Klein PD, Dudley M, Goddard-Finegold J, Mersmann HJ "Dietary cholesterol supplementation improves growth and behavioral response of pigs selected for genetically high and low serum cholesterol.." J. Nutr.. 1994 February ; 124 (2): 305-14. Pubmed PMID: 8308581
- Zhang S, Wong WW, Hachey DL, Pond WG, Klein PD "Dietary cholesterol inhibits whole-body but not cerebrum cholesterol synthesis in young pigs.." J. Nutr.. 1994 May ; 124 (5): 717-25. Pubmed PMID: 8169664
- Beckett PR, Wong WW, Copeland KC "Developmental changes in the relationship between IGF-I and body composition during puberty.." Growth Horm. IGF Res.. 1998 August ; 8 (4): 283-8. Pubmed PMID: 10984319
- Jensen CL, Butte NF, Wong WW, Moon JK "Determining energy expenditure in preterm infants: comparison of 2H(2)18O method and indirect calorimetry.." Am. J. Physiol.. 1992 September ; 263 (3): R685-92. Pubmed PMID: 1415659
- Delikanaki-Skaribas E, Trail M, Wong WW, Lai EC "Daily energy expenditure, physical activity, and weight loss in Parkinson's disease patients.." Mov. Disord.. 2009 April 15; 24 (5): 667-71. Pubmed PMID: 19117356
- Butte NF, Ellis KJ, Wong WW, Hopkinson JM, Smith EO "Composition of gestational weight gain impacts maternal fat retention and infant birth weight.." Am. J. Obstet. Gynecol.. 2003 November ; 189 (5): 1423-32. Pubmed PMID: 14634581
- Wong WW, Butte NF, Garza C, Klein PD "Comparison of energy expenditure estimated in healthy infants using the doubly labelled water and energy balance methods.." Eur J Clin Nutr. 1990 March ; 44 (3): 175-84. Pubmed PMID: 2369883
- Butte NF, Wong WW, Ferlic L, Smith EO, Klein PD, Garza C "Energy expenditure and deposition of breast-fed and formula-fed infants during early infancy.." Pediatr. Res.. 1990 December ; 28 (6): 631-40. Pubmed PMID: 2284162
- Wong WW "Energy expenditure of female adolescents.." J Am Coll Nutr. 1994 August ; 13 (4): 332-7. Pubmed PMID: 7963137
- Butte NF, Wong WW, Hopkinson JM, Heinz CJ, Mehta NR, Smith EO "Energy requirements derived from total energy expenditure and energy deposition during the first 2 y of life.." Am. J. Clin. Nutr.. 2000 December ; 72 (6): 1558-69. Pubmed PMID: 11101486
- Butte NF, Wong WW, Treuth MS, Ellis KJ, O'Brian Smith E "Energy requirements during pregnancy based on total energy expenditure and energy deposition.." Am. J. Clin. Nutr.. 2004 June ; 79 (6): 1078-87. Pubmed PMID: 15159239
- Butte NF, Moon JK, Wong WW, Hopkinson JM, Smith EO "Energy requirements from infancy to adulthood.." Am. J. Clin. Nutr.. 1995 November ; 62 (5): 1047S-1052S. Pubmed PMID: 7484920
- Butte NF, Wong WW, Hopkinson JM "Energy requirements of lactating women derived from doubly labeled water and milk energy output.." J. Nutr.. 2001 January ; 131 (1): 53-8. Pubmed PMID: 11208938
- Butte NF, Treuth MS, Mehta NR, Wong WW, Hopkinson JM, Smith EO "Energy requirements of women of reproductive age.." Am. J. Clin. Nutr.. 2003 March ; 77 (3): 630-8. Pubmed PMID: 12600853
- Wong WW, Stuff JE, Butte NF, Smith EO, Ellis KJ "Estimating body fat in African American and white adolescent girls: a comparison of skinfold-thickness equations with a 4-compartment criterion model.." Am. J. Clin. Nutr.. 2000 August ; 72 (2): 348-54. Pubmed PMID: 10919926
- Wong WW, Stuff JE, Butte NF, Smith EO, Ellis KJ "Estimation of body fat in Caucasian and African-American girls: total-body electrical conductivity methodology versus a four-component model.." Int. J. Obes. Relat. Metab. Disord.. 2000 September ; 24 (9): 1200-6. Pubmed PMID: 11033991
- Pivarnik JM, Bray MS, Hergenroeder AC, Hill RB, Wong WW "Ethnicity affects aerobic fitness in US adolescent girls.." Med Sci Sports Exerc. 1995 December ; 27 (12): 1635-8. Pubmed PMID: 8614319
- Wong WW, Hergenroeder AC, Stuff JE, Butte NF, Smith EO, Ellis KJ "Evaluating body fat in girls and female adolescents: advantages and disadvantages of dual-energy X-ray absorptiometry.." Am. J. Clin. Nutr.. 2002 August ; 76 (2): 384-9. Pubmed PMID: 12145011
- Morkeberg JC, Sheng HP, Wong WW "Extracellular water estimated by the bromide dilution method from samples of urine, saliva, and plasma.." Basic Life Sci.. 1990 55 : 55-9. Pubmed PMID: 2088308
- Butte N, Heinz C, Hopkinson J, Wong W, Shypailo R, Ellis K "Fat mass in infants and toddlers: comparability of total body water, total body potassium, total body electrical conductivity, and dual-energy X-ray absorptiometry.." J. Pediatr. Gastroenterol. Nutr.. 1999 August ; 29 (2): 184-9. Pubmed PMID: 10435656
- Butte NF, Villalpando S, Wong WW, Flores-Huerta S, Hernandez-Beltran MD, Smith EO "Higher total energy expenditure contributes to growth faltering in breast-fed infants living in rural Mexico.." J. Nutr.. 1993 June ; 123 (6): 1028-35. Pubmed PMID: 8505662
- Ellis KJ, Wong WW "Human hydrometry: comparison of multifrequency bioelectrical impedance with 2H2O and bromine dilution.." J. Appl. Physiol.. 1998 September ; 85 (3): 1056-62. Pubmed PMID: 9729583
- Hachey DL, Silber GH, Wong WW, Garza C "Human lactation. II: Endogenous fatty acid synthesis by the mammary gland.." Pediatr. Res.. 1989 January ; 25 (1): 63-8. Pubmed PMID: 2919120
- Butte NF, Villalpando S, Wong WW, Flores-Huerta S, Hernandez-Beltran MJ, Smith EO, Garza C "Human milk intake and growth faltering of rural Mesoamerindian infants.." Am. J. Clin. Nutr.. 1992 June ; 55 (6): 1109-16. Pubmed PMID: 1595582
- Motil KJ, Sheng HP, Montandon CM, Wong WW "Human milk protein does not limit growth of breast-fed infants.." J. Pediatr. Gastroenterol. Nutr.. 1997 January ; 24 (1): 41554. Pubmed PMID: 9093980
- Wong WW, Cochran WJ, Klish WJ, Smith EO, Lee LS, Klein PD "In vivo isotope-fractionation factors and the measurement of deuterium- and oxygen-18-dilution spaces from plasma, urine, saliva, respiratory water vapor, and carbon dioxide.." Am. J. Clin. Nutr.. 1988 January ; 47 (1): 41280. Pubmed PMID: 3122550
- Motil KJ, Schultz RJ, Wong WW, Glaze DG "Increased energy expenditure associated with repetitive involuntary movement does not contribute to growth failure in girls with Rett syndrome.." J. Pediatr.. 1998 February ; 132 (2): 228-33. Pubmed PMID: 9506632
- Butte NF, Wong WW, Hopkinson JM, Smith EO, Ellis KJ "Infant feeding mode affects early growth and body composition.." Pediatrics. 2000 December ; 106 (6): 1355-66. Pubmed PMID: 11099589
- Shulman RJ, Wong WW, Smith EO "Influence of changes in lactase activity and small-intestinal mucosal growth on lactose digestion and absorption in preterm infants.." Am. J. Clin. Nutr.. 2005 February ; 81 (2): 472-9. Pubmed PMID: 15699237
- Butte NF, Wong WW, Fiorotto M, Smith EO, Garza C "Influence of early feeding mode on body composition of infants.." Biol. Neonate. 1995 67 (6): 414-24. Pubmed PMID: 7578625
- Ellis KJ, Shypailo RJ, Wong WW "Measurement of body water by multifrequency bioelectrical impedance spectroscopy in a multiethnic pediatric population.." Am. J. Clin. Nutr.. 1999 November ; 70 (5): 847-53. Pubmed PMID: 10539745
- Wong WW, Hachey DL, Feste A, Leggitt J, Clarke LL, Pond WG, Klein PD "Measurement of in vivo cholesterol synthesis from 2H2O: a rapid procedure for the isolation, combustion, and isotopic assay of erythrocyte cholesterol.." J. Lipid Res.. 1991 June ; 32 (6): 1049-56. Pubmed PMID: 1940619
- Butte NF, Wong WW, Klein PD, Garza C "Measurement of milk intake: tracer-to-infant deuterium dilution method.." Br. J. Nutr.. 1991 January ; 65 (1): 41347. Pubmed PMID: 1997129
- Klish WJ, Karavias KE, White KS, Balch AJ, Fraley JK, Mikhail C, Abrams SH, Terrazas NL, Smith EO, Wong WW "Multicomponent School-initiated Obesity Intervention in a High-risk, Hispanic Elementary School.." J. Pediatr. Gastroenterol. Nutr.. 2012 January ; 54 (1): 113-6. Pubmed PMID: 21857252
- Patterson BW, Wong WW, Sheng HP, Mersmann HJ, Insull W, Klein PD, Fiorotto ML, Pond WG "Neonatal genetically lean and obese pigs respond differently to dietary cholesterol.." J. Nutr.. 1992 September ; 122 (9): 1830-9. Pubmed PMID: 1512632
- Hsu HW, Butte NF, Wong WW, Moon JK, Ellis KJ, Klein PD, Moise KJ "Oxidative metabolism in insulin-treated gestational diabetes mellitus.." Am. J. Physiol.. 1997 June ; 272 (6): E1099-107. Pubmed PMID: 9227457
- Hackman AM, Pond WG, Mersmann HJ, Wong WW, Krook LP, Zhang S "Obese pigs fed a high cholesterol diet from birth to 2 months are less susceptible than lean pigs to atherosclerosis.." J. Nutr.. 1996 February ; 126 (2): 564-73. Pubmed PMID: 8632232
- Bush CL, Pittman S, McKay S, Ortiz T, Wong WW, Klish WJ "Park-based obesity intervention program for inner-city minority children.." J. Pediatr.. 2007 November ; 151 (5): 513-7, 517.e1. Pubmed PMID: 17961696
- Sheng HP, Muthappa PB, Wong WW, Schanler RJ "Pitfalls of body fat assessments in premature infants by anthropometry.." Biol. Neonate. 1993 64 (5): 279-86. Pubmed PMID: 8297937
- Butte NF, Wong WW, Garza C "Prediction equations for total body water during early infancy.." Acta Paediatr.. 1992 March ; 81 (3): 264-5. Pubmed PMID: 1511204
- Ellis KJ, Shypailo RJ, Wong WW, Abrams SA "Prediction models for bone mineral content in school-aged children.." Ann. N. Y. Acad. Sci.. 2000 May ; 904 : 428-32. Pubmed PMID: 10865785
- Butte NF, Hsu HW, Thotathuchery M, Wong WW, Khoury J, Reeds P "Protein metabolism in insulin-treated gestational diabetes.." Diabetes Care. 1999 May ; 22 (5): 806-11. Pubmed PMID: 10332686
- Wong WW, Butte NF, Ellis KJ, Hergenroeder AC, Hill RB, Stuff JE, Smith EO "Pubertal African-American girls expend less energy at rest and during physical activity than Caucasian girls.." J. Clin. Endocrinol. Metab.. 1999 March ; 84 (3): 906-11. Pubmed PMID: 10084569
- Wong WW, Leggitt JL, Clarke LL, Klein PD "Rapid preparation of pyrogen-free 2H2(18)O for human-nutrition studies.." Am. J. Clin. Nutr.. 1991 March ; 53 (3): 585-6. Pubmed PMID: 2000811
- Ellis KJ, Shypailo RS, Steinberg FM, Lewis RD, Young RL, Wong WW "Reproducibility of fan-beam DXA measurements in adults and phantoms.." J Clin Densitom. 2004 7 (4): 413-8. Pubmed PMID: 15618602
- Wong WW, Nicolson M, Stuff JE, Butte NF, Ellis KJ, Hergenroeder AC, Hill RB, Smith EO "Serum leptin concentrations in Caucasian and African-American girls.." J. Clin. Endocrinol. Metab.. 1998 October ; 83 (10): 3574-7. Pubmed PMID: 9768667
- Wong WW, Lewis RD, Steinberg FM, Murray MJ, Cramer MA, Amato P, Young RL, Barnes S, Ellis KJ, Shypailo RJ, Fraley JK, Konzelmann KL, Fischer JG, Smith EO "Soy isoflavone supplementation and bone mineral density in menopausal women: a 2-y multicenter clinical trial.." Am. J. Clin. Nutr.. 2009 November ; 90 (5): 1433-9. Pubmed PMID: 19759166
- Ellis KJ, Shypailo RJ, Abrams SA, Wong WW "The reference child and adolescent models of body composition. A contemporary comparison.." Ann. N. Y. Acad. Sci.. 2000 May ; 904 : 374-82. Pubmed PMID: 10865775
- Wong WW, Clarke LL, Llaurador M, Ferlic L, Klein PD "The use of cotton balls to collect infant urine samples for 2H/1H and 18O/16O isotope ratio measurements.." Appl Radiat Isot. 1993 August ; 44 (8): 1125-8. Pubmed PMID: 8358400
- Hergenroeder AC, Wong WW, Fiorotto ML, Smith EO, Klish WJ "Total body water and fat-free mass in ballet dancers: comparing isotope dilution and TOBEC.." Med Sci Sports Exerc. 1991 May ; 23 (5): 534-41. Pubmed PMID: 2072831
- Cochran WJ, Wong WW, Fiorotto ML, Sheng HP, Klein PD, Klish WJ "Total body water estimated by measuring total-body electrical conductivity.." Am. J. Clin. Nutr.. 1988 October ; 48 (4): 946-50. Pubmed PMID: 3048079
- Butte NF, Barbosa L, Villalpando S, Wong WW, Smith EO "Total energy expenditure and physical activity level of lactating Mesoamerindians.." J. Nutr.. 1997 February ; 127 (2): 299-305. Pubmed PMID: 9039831
- Wong WW "Total energy expenditure of free-living humans can be estimated with the doubly labeled water method.." Adv. Food Nutr. Res.. 1996 40 : 171-80. Pubmed PMID: 8858813
- Butte NF, Wong WW, Adolph AL, Puyau MR, Vohra FA, Zakeri IF "Validation of cross-sectional time series and multivariate adaptive regression splines models for the prediction of energy expenditure in children and adolescents using doubly labeled water.." J. Nutr.. 2010 August ; 140 (8): 1516-23. Pubmed PMID: 20573939
- Hergenroeder AC, Hill RB, Wong WW, Sangi-Haghpeykar H, Taylor W "Validity of self-assessment of pubertal maturation in African American and European American adolescents.." J Adolesc Health. 1999 March ; 24 (3): 201-5. Pubmed PMID: 10195803
- Ellis KJ, Shypailo RJ, Hardin DS, Perez MD, Motil KJ, Wong WW, Abrams SA "Z score prediction model for assessment of bone mineral content in pediatric diseases.." J. Bone Miner. Res.. 2001 September ; 16 (9): 1658-64. Pubmed PMID: 11547835
Memberships
- American Institute of Nutrition
- Member (03/1988)
Funding
- Dietary Composition and Energy Expenditure During Weight-Loss Maintenance - #0000563867
- $1,183,447.00 (03/01/2014 - 06/30/2017) Grant funding from Nutrition Science Initiative
- To understand the effect of dietary composition on energy expenditure during weight-loss maintenance.
- Study of Latinos-Nutrition & Physical Activity Assessment Study (SOLNAS) - #1R01 HL095856-01A1
- $472,514.00 (04/25/2010 - 03/31/2015) Grant funding from NIH
- To document the measurement errors on subjective dietary and physical activity instruments against validated biomarker measurements among Latinos.
- Prenatal Stress Biology, Infant Body Composition and Obesity Risk - #5R01 HD065825-02
- $286,033.00 (07/01/2011 - 06/30/2015) Grant funding from NIH
- To document the association between infant body composition and obesity risk.
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