Lauren Goldie, BSc(Hons), PhD, CCRP
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Positions
- Assistant Professor of Surgery
-
Division of Congenital Heart Surgery
Baylor College of Medicine
- Director of Clinical Research
-
Division of Congenital Heart Surgery
Baylor College of Medicine
Education
- PhD from The University of Western Australia
- 08/2003 - Perth, Western Australia Australia
- Biochemistry & Molecular Biology
- Postdoctoral Training at Baylor College Of Medicine
- 08/2008 - Houston, Texas United States
- Developmental Vascular Biology & Hematopoiesis
- BSc from The University of Western Australia
- 12/1998 - Perth, Western Australia Australia
- Biochemistry & Molecular Biology
Certifications
- Certified Clinical Research Professional (CCRP)
- Society of Clinical Research Associates (SoCRA)
Professional Interests
- Clinical research operations and regulatory affairs
- Developmental vascular biology and hematopoiesis
- Molecular cell biology and regenerative medicine
Websites
Selected Publications
- Marcelo KL, Sills TM, Coskun S, Vasavada H, Goldie LC, Hirschi KK "Retinoic acid regulation of hemogenic endothelial cell specification requires c-Kit, Notch signaling and p27-mediated cell cycle control.." Dev. Cell.2013;27:504-515.
- Goldie LC, Kelly MA, Hirschi KK "A natural history of the endothelial cell: from specification to specialization.." Trends Dev. Biol..2011;5:17-27.
- Kendrick TS, Lipscombe RJ, Rausch O, Nicholson SE, Layton JE, Goldie-Cregan LC, Bogoyevitch MA "Contribution of the membrane distal tyrosine in intracellular signaling by the granulocyte colony-stimulating factor receptor.." J. Biol. Chem..2004;279(1):326-340. Pubmed PMID: 14557262
- Goldie-Cregan LC, Croager EJ, Abraham LJ "Characterization of the murine CD153 gene: gene structure and expression.." Tissue Antigens.2002;60:139-146. Pubmed PMID: 12392508
- Marcelo KL, Goldie LC, Hirschi KK "Regulation of endothelial cell differentiation and specification.." Circ. Res.. 2013 112 (9): 1272-1287. Pubmed PMID: 23620236
- Chaudhury H, Goldie LC, Hirschi KK "Vascular precursor cells.." Genes Cancer. 2012 2 (12): 1081-1084. Pubmed PMID: 22866199
- Goldie LC, Lucitti JL, Dickinson ME, Hirschi KK "Cell signaling directing the formation and function of hemogenic endothelium during murine embryogenesis.." Blood. 2008 112 (8): 3194-3204. Pubmed PMID: 18684862
- Karimi M, Goldie LC, Ulgiati D, Abraham LJ "Integration site-specific transcriptional reporter gene analysis using Flp recombinase targeted cell lines.." BioTechniques. 2007 42 (2): 217-224. Pubmed PMID: 17373487
- Karimi M, Goldie LC, Cruickshank MN, Moses EK, Abraham LJ "A critical assessment of the factors affecting reporter gene assays for promoter SNP function: a reassessment of -308 TNF polymorphism function using a novel integrated reporter system.." Eur. J. Hum. Genet.. 2009 17 (11): 1454-1462. Pubmed PMID: 19471307
- Goldie LC, Kelly MA, Hirschi KK "Embryonic vasculogenesis and hematopoietic specification.." Organogenesis. 2008 4 (4): 257-263. Pubmed PMID: 19337406
- Chaudhury H, Raborn E, Goldie LC, Hirschi KK "Stem cell-derived vascular endothelial cells and their potential application in regenerative medicine.." Cells Tissues Organs. 2011 195 (1): 41-47. Pubmed PMID: 22005724
- Marcelo KL, Lin F, Rajapakshe K, Dean A, Gonzales N, Coarfa C, Means AR, Goldie LC and York B "Deciphering hepatocellular responses to metabolic and oncogenic stress.." J. Biol. Methods. 2015 2 (3): e28.
- Lin F, Marcelo KL, Rajapakshe K, Coarfa C, Dean A, Wilganowski N, Robinson H, Sevick E, Bissig KD, Goldie LC, Means AR and York, B "The CaMKK2/CaMKIV relay is an essential regulator of hepatic cancer.." Hepatology. 2015 62 (2): 505-520.
Memberships
- North American Vascular Biology Organization (NAVBO)
- Professional Member
- American Heart Association (AHA)
- Professional Member
- American Association for the Advancement of Science (AAAS)
- Professional Member
- Cardiovascular Research Institute (CVRI) at Baylor College of Medicine
- Member
- Society of Clinical Research Associates (SoCRA)
- Professional Member
- Regulatory Affairs Professionals Society (RAPS)
- Professional Member
- The Union of Concerned Scientists
- Professional Member
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