Positions
- Associate Professor of Surgery
-
Division of Congenital Heart Surgery
Baylor College of Medicine
Addresses
- Texas Children's Hospital (Lab)
-
Room: TXCH-B19
Houston, TX 77030
United States
Education
- Postdoctoral Fellowship at Baylor College Of Medicine
- Houston, TX United States
- PhD from University Of London
- London, United Kingdom
- MS from Garhwal University
- Srinagar, India
- BS from Garhwal University
- Srinagar, India
Professional Interests
- Pediatric developmental disorders
- Cardiovascular genetics
- Somatic mosaicism
- Autoimmunity and heart disease pathways
- Biobanking
Professional Statement
Dr. Wadhwa joined BCM as a postdoctoral fellow and subsequently as a faculty member. She has a broad academic and research background in pediatric developmental disorders, with a particular focus on congenital heart disease (CHD). Her research explores the molecular and genetic mechanisms underlying complex CHD, with recent work emphasizing the role of somatic mosaicism in its pathogenesis. Dr. Wadhwa has established one of the nation's largest and most robust CHD Tissue Banks, a resource supporting numerous research initiatives within the Heart Center. She earned her doctoral degree in Biotechnology from the University of London, UK, and gained postdoctoral training at the University of Dundee, Scotland, UK, and the Department of Pediatrics, Baylor College of Medicine.Websites
Selected Publications
- Yu L, Baxter PA, Zhao X, Liu Z, Wadhwa L, Zhang Y, Su JM, Tan X, Yang J, Adesina A, Perlaky L, Hurwitz M, Idamakanti N, Police SR, Hallenbeck PL, Blaney SM, Chintagumpala M, Hurwitz RL, Li XN "A single intravenous injection of oncolytic picornavirus SVV-001 eliminates medulloblastomas in primary tumor-based orthotopic xenograft mouse models.." Neuro-oncology. 2011 Jan;13(1):14-27. Pubmed PMID: 21075780
- Sharma JB, Wadhwa L, Malhotra M, Arora R, Singh S "A case of huge enlargement of cystosarcoma phylloides of breast in pregnancy.." Eur. J. Obstet. Gynecol. Reprod. Biol..;115(2):237-9. Pubmed PMID: 15262364
- Song J, Wadhwa L, Bejjani BA, O'Brien WE "Determination of 3-keto-4-ene steroids and their hydroxylated metabolites catalyzed by recombinant human cytochrome P450 1B1 enzyme using gas chromatography-mass spectrometry with trimethylsilyl derivatization.." J. Chromatogr. B Analyt. Technol. Biomed. Lif. 2003 Jul 5;791(41276):127-35. Pubmed PMID: 12798173
- Tempe A, Singh S, Wadhwa L, Garg A "Conventional and color Doppler sonography in preoperative assessment of ovarian tumors.." Int J Gynaecol Obstet. 2006 Jan;92(1):64-8. Pubmed PMID: 16303129
- Bond WS, Wadhwa L, Perlaky L, Penland RL, Hurwitz MY, Hurwitz RL, Chèvez-Barrios P "Establishment and propagation of human retinoblastoma tumors in immune deficient mice.." J Vis Exp.;(54) Pubmed PMID: 21847079
- Malhotra M, Sharma JB, Wadhwa L, Singh S "Disseminating myxoid leiomyosarcoma of the uterus.." Arch. Gynecol. Obstet..;271(2):166-7. Pubmed PMID: 14749942
- Wadhwa L, Utreja A, Tewari A "A study of clinical signs and symptoms of temporomandibular dysfunction in subjects with normal occlusion, untreated, and treated malocclusions.." Am J Orthod Dentofacial Orthop. 1993 Jan;103(1):54-61. Pubmed PMID: 8422032
- Wadhwa L, Bond WS, Perlaky L, Overbeek PA, Hurwitz MY, Chévez-Barrios P, Hurwitz RL "Embryonic Retinal Tumors in SV40 T-Ag Transgenic Mice Contain CD133+ Tumor-Initiating Cells.." Invest. Ophthalmol. Vis. Sci..;53(7):3454-62. Pubmed PMID: 22562503
- Chaudhuri SR, Mallam JN, Chévez-Barrios P, Wadhwa L, Ng P, Hurwitz MY, Hurwitz RL "Modulation of adenoviral transduction in vitro and in vivo by hyaluronan and its receptor CD44.." Mol. Ther.. Mar;15(3):566-70. Pubmed PMID: 17180120
- Sharma JB, Wadhwa L "Recurrent aggressive angiomyxoma of vagina--a case report.." Indian J Pathol Microbiol.;47(3):425-7. Pubmed PMID: 16295447
- Singh S, Singh B, Bahuguna R, Wadhwa L, Saxena R "Stress degradation studies on ezetimibe and development of a validated stability-indicating HPLC assay.." J Pharm Biomed Anal. 7;41(3):1037-40. Pubmed PMID: 16495029
- Wadhwa L, Hurwitz MY, Chévez-Barrios P, Hurwitz RL "Treatment of invasive retinoblastoma in a murine model using an oncolytic picornavirus.." Cancer Res..;67(22):10653-6. Pubmed PMID: 18006805
- Arnav Adhikari , G Vick Wesley 3rd , Minh B Nguyen, Tam T Doan , Mounica Y Rao , Anitha Parthiban , Lance Patterson , Kashika Adhikari , David Ouyang , Jeffery S Heinle , Lalita Wadhwa "Predicting Cardiac Magnetic Resonance-Derived Ejection Fraction from Echocardiogram Via Deep Learning Approach in Tetralogy of Fallot." Pediatr Cardiol.; Pubmed PMID: 40038120
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