Katarzyna Kent, Ph.D.

Email

kkent@bcm.edu

Education

PhD from Baylor College of Medicine: 02/2025 - Houston, Texas, United States

BS from University of Houston: Houston, Texas, United States; Molecular and Cellular Biology

Certifications

HT: American Society for Clinical Pathology

Websites

Center for Drug Discovery

Selected Publications

Kaori Nozawa, Thomas X Garcia, Katarzyna Kent, Mei Leng, Anna Malovannaya, Fei Yuan, Zhifeng Yu, Masahito Ikawa, Martin M. Matzuk. " Testis-specific serine kinase 3 is required for sperm morphogenesis and male fertility " Andrology. 2022 Oct 28;
Pubmed PMID: 36306217.
Kaori Nozawa, Yoshitaka Fujihara, Darius J Devlin, Ricardo E Deras, Katarzyna Kent, Irina V Larina , Kohei Umezu, Zhifeng, Courtney M Sutton, Qiuji Ye, Laura K Dean, Chihiro Emori, Masahito Ikawa, Thomas X Garcia, Martin M Matzuk. " The testis-specific E3 ubiquitin ligase RNF133 is required for fecundity in mice. " BMC Biology. 2022 Jul 13; 161 (20)
Pubmed PMID: 35831855.
Robertson MJ, Kent K, Tharp N, Nozawa K, Dean L, Mathew M, Grimm SL, Yu Z, Légaré C, Fujihara Y, Ikawa M, Sullivan R, Coarfa C, Matzuk MM & Garcia TX.. " Large-scale discovery of male reproductive tract-specific genes through analysis of RNA-seq datasets. " BMC Biology. 2020 ; 103 (18)
Pubmed PMID: 32814578.
Kent K, Johnston M, Strump N, Garcia TX.. " Toward Development of the Male Pill: A Decade of Potential Non-hormonal Contraceptive Targets " Frontiers in Cell and Developmental Biology. 2020 Feb 26;
Pubmed PMID: 32161754.
Holcomb RJ, Oura S, Nozawa K, Kent K, Yu Z, Robertson MJ, Coarfa C, Matzuk MM, Ikawa M & Garcia TX.. " The testis-specific serine proteases PRSS44, PRSS46, and PRSS54 are dispensable for male mouse fertility " Biology of Reproduction. 2020 Jan 1; 102 (1) : 84-91.
Pubmed PMID: 31403672.
Courtney Sutton, Kaori Nozawa, Katarzyna Kent, Alexander Saltzman, Mei Leng, Sureshbabu Nagarajan, Anna Malovannaya, Masahito Ikawa Thomas X Garcia, Martin M Matzuk. " Molecular dissection and testing of PRSS37 function through LC-MS/MS and the generation of a PRSS37 humanized mouse model " Sci Rep.. 2023 Jul 14;
Pubmed PMID: 37452050.
Katarzyna Kent, Kaori Nozawa, Courtney Sutton, Frey Daniel, Masahito Ikawa, Thomas X Garcia, Martin M Matzuk. " CUB domains are not required for OVCH2 function in sperm maturation in the mouse epididymis " Andrology. 2023 Aug 8;
Pubmed PMID: 37551853.
Ku A, Sharma K, Ta H, Sutton C, Bohren K, Wang Y, Chamakuri S, Chen R, Hakenjos J, Jimmidi R, Kent K, Li F, Li J, Ma L, [...], Young D, Teng M, Kim C, Matzuk M. " Reversible male contraception by targeted inhibition of serine/threonine kinase 33 " Science. 2024 May 23; 384 (6698) : 885-890.
Pubmed PMID: 38781365.
Katarzyna Kent, Kaori Nozawa, Rachel Parkes, Laura Dean, Frey Daniel, Mei Leng, Antrix Jain, Anna Malovannaya, Martin M Matzuk, Thomas X Garcia. " Large-scale CRISPR/Cas9 deletions within the WFDC gene cluster uncover gene functionality and critical roles in mammalian reproduction " PNAS. 2024 Dec 17; 121 (51)
Pubmed PMID: 39665756.
Katarzyna Kent, Kaori Nozawa, Antrix Jain, Anna Malovannaya, Thomas X Garcia, Martin M Matzuk. " Ovochymase 2 is a key regulatory factor modulating proteolytic pathways and sperm maturation in the mammalian epididymis " Biol Reprod. 2025 Jul 13; 113 (1) : 127-140.
Pubmed PMID: 40155198.

Funding

T32 - Comprehensive Mechanisms in Reproductive Sciences: NICHD