John Moore Vierling, MD, FACP, FAASLD, AGAF
Professor of Medicine, Transplant Hepatology Medical Director
(832) 355-1400Positions
- Professor of Medicine, Transplant Hepatology Medical Director
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Medicine
Section of Gastroenterology and Hepatology
Baylor College of Medicine
Houston, Texas, United States
Tenured
- Chief of Hepatology
-
Medicine
Section of Gastroenterology and Hepatology
Baylor College of Medicine
Houston, Texas, United States
- Director, Baylor Liver Health
-
Medicine
Section of Gastroenterology and Hepatology
Baylor College of Medicine
Houston, Texas, United States
- Professor of Surgery
-
Surgey
Division of Abdominal Transplantation
Baylor College of Medicine
Houston, Texas, United States
Tenured
- Director, Advanced Liver Therapies at St. Luke's Medical Center
-
Medicine
Section of Gastroenterology and Hepatology
Baylor College of Medicine
Houston, Texas, United States
Addresses
- Abdominal Transplant & Liver Disease (Clinic)
-
Baylor Clinic
6620 Main Street, Suite 1450
Houston, TX, 77030
United States
SCHEDULE APPOINTMENT - (832) 355-1400
- Advanced Liver Therapies (Lab)
-
Baylor Clinic
6620 Main Street
Houston, TX, 77030
United States
Phone: (713) 798-1966
https://www.bcm.edu/research/labs-and-centers/research-centers/advanced-liver-therapies-research/clinical-trials
- Department of Surgery (Office)
-
Baylor College of Medicine
One Baylor Plaza
Houston, TX, 77030
United States
Education
- Residency at University of Rochester Strong Memorial Hospital
- 06/1974 - Rochester, New York, United States
- MD from Stanford University School of Medicine
- 06/1972 - Stanford, California, United States
- Medicine
- Fellowship at University of California, San Francisco School Of Medicine
- 06/1978 - San Francisco, California, United States
- Research Fellowship at National Institutes of Health
- 06/1977 - Bethesda, Maryland, United States
Certifications
- Diplomate - Transplant Hepatology
- American Board of Internal Medicine
- Diplomate - Gastroenterology
- American Board of Internal Medicine
- Diplomate - Internal Medicine
- American Board of Internal Medicine
- Diplomate
- National Board of Medical Examiners
Honors & Awards
- Distinguished Scientist Award
- St. Luke's Hospital
- George Jamieson Award for Outstanding Public Service
- American Liver Foundation
- Best Doctors in America
- Awardee of 20 Consecutive Years of Selection by Peers
- American Health (01/2000)
- America’s Top Doctors
- Castle Connolly Medical Ltd.
- Who’s Who in America
- America’s Registry of Outstanding Professionals
- Who’s Who in Science and Engineering
- Who's Who in the World
- Selected annually since 2017
- Marquis Who's Who (01/2017)
- Chairman, Board of Directors
- Development of SEPET (TM) Liver Assist Device
- Arbios Systems, Inc. (01/1999 - 08/2008)
- Member, Board of Directors
- Independent Member of BOD for Athenex, Inc. that focuses on the discovery, development and commercialization of novel therapeutics for cancer.
- Athenex, Inc. (01/2019)
Professional Interests
- Transplant Hepatology
- Pre- and post-liver transplantation care
- Liver failure
- Hepatitis
- Cirrhosis
- Primary sclerosing cholangitis
- Drug-induced liver injury
- Wilson disease
- Hemochromatosis
- Alpha-1-antitrypsin deficiency
- Hepatocellular carcinoma (HCC) and cholangocarcinoma,
- Gastroesophageal varices
- Hepatic encephalopathy
Professional Statement
Dr. Vierling is board certified in internal medicine and gastroenterology and was previously certified in Transplant Hepatology from 2006-2016. He is a Fellow of the American College of Physicians, Fellow of the American Association for the Study of Liver Diseases and an American Gastroenterology Association Fellow. He was the founding Medical Director of Liver Transplantation and Director of Hepatology and instrumental in the founding of the current liver transplant program at the University of Colorado Health Sciences Center. He was subsequently the founding Medical Director of Liver Transplantation and Director of Hepatology at Cedars-Sinai Medical Center/UCLA. After 10 years as Medical Director of Liver Transplantation, he became the Medical Director of Multi-Organ Transplantation at Cedars-Sinai/UCLA.
Dr. John M. Vierling directs Advanced Liver Therapies, a clinical research unit devoted to hepatobiliary diseases. He and his research staff are conducting phase 1-3 studies of diagnostics and therapies in chronic hepatitis B, chronic hepatitis C, primary biliary cirrhosis, non-alcoholic fatty liver disease, anti-fibrotic therapy to prevent cirrhosis, hepatic encephalopathy, and measurement of hepatocellular function using 13C-labeled compounds.
Dr. John M. Vierling directs Advanced Liver Therapies, a clinical research unit devoted to hepatobiliary diseases. He and his research staff are conducting phase 1-3 studies of diagnostics and therapies in chronic hepatitis B, chronic hepatitis C, primary biliary cirrhosis, non-alcoholic fatty liver disease, anti-fibrotic therapy to prevent cirrhosis, hepatic encephalopathy, and measurement of hepatocellular function using 13C-labeled compounds.
Dr. Vierling’s primary research interests are the immunopathogenic mechanisms involved in hepatobiliary injury caused by viral infection, autoimmunity, alloimmunity, and non-alcoholic fatty liver disease. By emphasizing a "laboratory bench to bedside" philosophy, Dr. Vierling has also been active in the design and execution of clinical therapeutic trials of antiviral agents for treatment of hepatitis B and C infections in patients before and after liver transplantation, and trials of immunosuppressive drugs in liver transplantation and autoimmune liver diseases.
Dr. Vierling’s basic science laboratory investigations have used murine models to study the immunopathogenesis of non-suppurative destructive cholangitis, which destroys bile ducts in primary biliary cirrhosis, an autoimmune liver disease, as well as in two alloimmune diseases, hepatic allograft rejection and chronic graft-versus-host disease. Dr. Vierling is the author of numerous research publications.
Websites
Dr. Vierling's Care Centers
Abdominal Transplant and Liver Disease Clinic
What's in a Name? Change Underway for PBC
The transplant hepatology team has provided leadership for an ambitious international initiative to formally change the name of PBC from “Primary Biliary Cirrhosis” to “Primary Biliary Cholangitis.”
Selected Publications
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Bourlière M, Gordon SC, Flamm SL, Cooper CL, Ramji A, Tong M, Ravendhran N, Vierling JM, et al. " Sofosbuvir, Velpatasvir, and Voxilaprevir for Previously Treated HCV Infection " N Engl J Med. ;
Pubmed PMID: 28564569. -
Bacon BR, Gordon SC, Lawitz E, Marcellin P, Vierling JM, Zeuzem S, Poordad F, Goodman ZD, Sings HL, Boparai N, Burroughs M, Brass CA, Albrecht JK, Esteban R. " Boceprevir for previously treated chronic HCV genotype 1 infection. " N. Engl. J. Med.. 2011 Mar 31; 364 (13) : 1207-17.
Pubmed PMID: 21449784. -
Hwang JP, Mohseni M, Gor BJ, Wen S, Guerrero H, Vierling JM. " Hepatitis B and hepatitis C prevalence and treatment referral among Asian Americans undergoing community-based hepatitis screening. " Am J Public Health. 2010 Apr 1; 100 : S118-24.
Pubmed PMID: 20147697. -
Ilyas JA, Vierling JM. " An overview of emerging therapies for the treatment of chronic hepatitis C. " Clin Liver Dis. 2011 Aug ; 15 (3) : 515-36.
Pubmed PMID: 21867934.
Memberships
- American Association for the Study of Liver Diseases
- President, 2006
- American Gastroenterological Association
- Fellow
- American Liver Foundation:
- (01/1979 - 06/2020)
- American Clinical and Climatological Association
- European Association for the Study of the Liver
- Member (01/1990)
- Asian Pacific Association for the Study of the Liver
- Member (01/2004)
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