The section of Neurology and Developmental Neuroscience at Baylor College of Medicine was officially organized in 1979 under the direction of Dr. Marvin Fishman. During his tenure, the neurology program achieved national recognition and developed a reputation for excellence in clinical neurological training. Many fellow program participants have gone on to distinguished medical careers and won prestigious awards.

Baylor Pediatric Neurology and Developmental Neuroscience has had a long and rewarding relationship with Texas Children's Blue Bird Circle Clinic for Pediatric Neurology, originally founded in 1949. For years, Baylor neurologists have provided patient care through their affiliation with the Blue Bird Circle Clinic. In 1998, the Blue Bird Clinic formed an official partnership with Texas Children's and moved into spacious new quarters within the Clinical Care Center building.

Basic neuroscience research commenced in 1992 with the founding of The Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories. Guided by Scientific Director Dr. John Swann, the Cain Foundation Laboratories investigate the causes of epilepsy and other disorders of neurological development and provide multidisciplinary research training for young neuroscientists. In addition, the neurogenetics laboratory of Dr. Huda Zoghbi conducts important neuroscience research in several areas that has led to landmark discoveries in Rett syndrome and other neurodegenerative disorders.

Dr. Gary Clark became chief of Pediatric Neurology and Developmental Neuroscience in 2004. During his tenure, Dr. Clark has recruited several highly-qualified faculty members and fellows to further develop a growing and dynamic child neurology program. Under Dr. Clark's direction, Baylor Pediatric Neurology and Developmental Neuroscience is committed to developing research that translates new scientific discoveries into effective bedside treatments and is strongly committed to addressing the significant challenges present in today's changing healthcare environment.