Department of Medicine

Funding and Grants

Master
Content

Aladin Boriek, Ph.D

Grant Title: RPPR (MPI): Short Term Training to Increase Diversity – HL108853
Funding Agency: National Heart, Lung and Blood Institute (NHLBI)
Role: Principal Investigator 

Grant Title: NCE: Exploratory Role of the Cytoskeleton in Anisotropic Regulation of MicroRNAs in Skeletal Muscles - 1714478
Funding Agency: National Science Foundation (NSF)
Role: Principal Investigator

Grant Title: Exploratory Role of the Cytoskeleton in Anisotropic Regulation of MicroRNAs in Skeletal Muscles - 1714478
Funding Agency: National Science Foundation (NSF)
Role: Principal Investigator

Kalpalatha Guntupalli, M.D.

Grant Title: Idiopathic Pulmonary Fibrosis Prospective Outcomes Registry (IPF-PRO) and Chronic Fibrosing Interstitial Lung Disease with Progressive Phenotype Prospective Outcomes (ILD-PRO) Registry
Funding Agency: Boehringer Ingelheim Ltd 
Role: Site-Principal Investigator

Grant Title: Idiopathic Pulmonary Fibrosis (IPF) Prospective Outcomes Registry (IPF-PRO, ILD-PRO)
Funding Agency: Duke University
Role: Site Principal Investigator

Grant Title: Functional roles of Nrf2 and NQO1 genetic variants in hyperoxic lung injury-ARDS
Funding Agency: NIH  
Role: Co-Investigator

Nicola Hanania, M.D.

Grant Title: Airways Clinical Research Centers (ACRC) 
Funding Agency: American Lung Association 
Role: Principal Investigator

Grant Title: Project Extension (NCE)- Losartan Effects on Emphysema Progression Trial (LEEP) Trial 
Funding Agency: American Lung Association 
Role: Principal Investigator

Grant Title: The Genetics Epidemiology of COPD – 2U01-HL089897
Funding Agency: National Institutes of Health (NIH) 
Role: Principal Investigator

Grant Title: Network Management Core (NEMO) for the Pulmonary Trials Cooperative (PTC) (RETHINC) – 5U01-HL128954-04
Funding Agency: National Heart, Lung and Blood Institute (NHLBI) 
Role: Principal Investigator

Grant Title: Network Management Core (NEMO) for the Pulmonary Trials Cooperative (PTC)/ Insight: Pulmonary Trials Cooperative (PTC) Intervention Study in Overweight Patient with COPD (Insight COPD) Trial – HL128954
Funding Agency: National Heart, Lung and Blood Institute (NHLBI)
Role: Principal Investigator

Grant Title: A Phase 2B, Randomized, Double-blind, Placebo-controlled, Dose-ranging, Multi-center Study to Evaluate the Efficacy and Safety of GB001 as Maintenance Therapy in Adult Subjects with Moderate to Severe Asthma 
Funding Agency: Gossamer Bio   
Role: Site-Principal Investigator

Grant Title: A Randomized, Double-blind, Placebo-controlled, Parallel-group, 52-Week Pivotal Study to Assess the Efficacy, Safety, and Tolerability of Dupilumab in Patients with Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD) with Type 2 Inflammation
Funding Agency: Sanofi U.S.  
Role: Site-Principal Investigator

Grant Title: A 24-Week Multi-center, Double-blind, Placebo Controlled Dose-range Finding Study to Investigate the Efficacy and Safety or Oral QBW251 in COPD Patients on Triple Inhaled Therapy (LABA/LAMA/ICS)
Funding Agency: Novartis Pharmaceuticals Corp 
Role: Site-Principal Investigator

Grant Title: A Phase IIA, Multicenter, Randomized, Placebo-controlled, Double-blind Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of MTPS9579A in Patients with Asthma Requiring Inhaled Corticosteroids and a Second Controller 
Funding Agency: Genetech, Inc. 
Role: Site-Principal Investigator

Grant Title: Asthma BMI Baseline Study (ABBS) Under Master ACRC Network (47412-N2)
Funding Agency: American Lung Association   
Role: Principal Investigator

Grant Title: Observational Study in Healthy Subjects and Patients with COPD to Assess the Relationship Between Clinical, Imaging and Biomarker Measurements, and Progression of Emphysema Over Three Years [Footprints]. (Emphysema Progression Biomarker Study) 
Funding Agency: Boehringer Ingelheim Pharmaceutical, 
Role: Principal Investigator

Farrah Kheradmand, M.D. 

Grant Title: Enhancement of Immune Memory Responses to Respiratory Infection - PR140593P1
Funding Agency: Department of Defense Congressionally Directed Medical Research Programs 
Role: Principal Investigator

Grant Title: Toxic Effects of E-Cigs Following Transition from Conventional Cigarettes – 5R01-ES029442-02
Funding Agency: National Institutes of Health (NIH) 
Role: Principal Investigator

Grant Title: Fungal Pathogenesis of Moderate to Severe Asthma – R01Al135803-01
Funding Agency: National Institutes of Health (NIH)
Role: Co-Principal Investigator 

Grant Title: Mechanism and Function of Let-7, a Novel Modulator of Th17-Dependent 
Emphysema – R01HL140398-01
Funding Agency: National Institutes of Health (NIH)
Role: Co-Principal Investigator 

Grant Title: Mariposa: Roche-Genentech - CA42481                           Funding Agency: Multicenter Cooperative Trial with Veteran Affairs Medical Center  
Role: Principal Investigator- Kheradmand

Grant Title: Innate and Acquired Immune Responses in Human COPD
Funding Agency: Clinical Science Research & Development Merit Review 
Role: Principal Investigator

Grant Title: CMA: Pulmonary and Systemic Effects of Deployment Related Particulate Matter Exposures 
Funding Agency: Clinical Science Research & Development Merit Review 
Role: Co-Principal Investigator

Sara Nowakowski, Ph.D.

Grant Title: Effectiveness of Healthy Sleep Habits for Hospitalized Older Adults to Optimize Rehabilitation – R01NR018342
Funding Agency: National Institutes of Health (NIH) – National Institute of Nursing Research Grant
Role: Principal Investigator 

Grant Title: Effectiveness of Healthy Sleep Habits for Hospitalized Older Adults to Optimize Rehabilitation
Funding Agency: National Institutes of Health (NIH)- National Institute of Aging 
Role: Principal Investigator 

Lavannya Pandit, M.D.

Grant Title: G6PD Deficiency Predicts Outcomes from COVID-19 Infection amongst Veterans at Highest Risk for Severity of Illness 
Funding Agency: Department of Veterans Affairs 
Role: Principal Investigator
      
Grant Title: Neutrophil Exosomes: New Pathogenic Entities in COPD 
Funding Agency: Department of Veterans Affairs, (Gaggar) 
Role: Co-Principal Investigator

Grant Title: EMPACTA: Genentech - ML42528                                         Funding Agency: Multicenter Cooperative Trial with Veterans Affairs Medical Center 
Role: Co-Principal Investigator (Principal Investigator: Trautner)
 
Grant Title: Mariposa: Roche-Genentech - CA42481                              Funding Agency: Multicenter Cooperative Trial with Veteran Affairs Medical Center  
Role: Co-Principal Investigator (Principal Investigator- Kheradmand)

Freddy Romero, Ph.D.

Grant Title: Proteasome Degradation of p53 Drives HPS Lung Fibrosis - 1R01HL136833-01A1
Funding Agency: National Heart, Lung, and Blood Institute, NIH
Role: Principal Investigator

Ivan Rosas, M.D.

Grant Title: Normal Aging Lung Cell Atlas (NALCA) – U01HL145567
Funding Agency: National Institutes of Health (NIH) 
Role: Co-Investigator

Grant Title: Epithelial Protective Effects of Thyroid Hormone Signaling in Fibrosis – R01HL141852
Funding Agency: National Institutes of Health (NIH)
Role: Co-Investigator

Grant Title: Autoantibody- Targeted Therapy for Acute Exacerbations of Idiopathic Pulmonary Fibrosis – U01HL133232 
Funding Agency: National Institutes of Health (NIH)
Role: Multi Principal Investigator

Grant Title: Research Training in Lung Disease – T32HL00747-24
Funding Agency: National Heart, Lung and Blood Institute (NHLBI) 
Role: Principal Investigator

Grant Title: A Randomized Double-blind, Placebo-controlled Multicenter Study to Evaluate the Safety and Efficacy of Tocilizumab in Patients with Severe COVID-19 Pneumonia (COVACTA) 
Funding Agency: Hoffmann La Roche, Inc. 
Role: Site-Principal Investigator

Grant Title: A Randomized, Double-blind, Placebo-controlled Phase 2 Study of Safety, Tolerability and Efficacy of Pirfenidone in Patients with Rheumatoid Arthritis Interstitial Lung Disease 
Funding Agency: Genentech, Inc.  
Role: Overall Principal Investigator

Grant Title: A Phase III, Randomized, Double-blind, Multicenter Study to Evaluate the Efficacy and Safety of Remdesivir Plus Tocilizumab Compared with Remdesivir Plus Placebo in Hospitalized Patients with Severe COVID-19 Pneumonia 
Funding Agency: F. Hoffmann-La Roche Ltd 
Role: Site-Principal Investigator

Grant Title: Clinical Genetics and Screening for Pulmonary Fibrosis – R01HL130974
Funding Agency: National Heart, Lung and Blood Institute (NHLBI)
Role: Co-Principal Investigator 

Grant Title: Molecular Profiles of Smokers with Subclinical Interstitial Lung Disease – PR171782
Funding Agency: Department of Defense
Role: Principal Investigator 

Rolando Rumbaut, M.D., Ph.D.

Grant Title: Collaborative Research Training in Thrombosis and Inflammation – T32HL139425
Funding Agency: National Heart, Lung and Blood Institute (NHLBI) 
Role: Principal Investigator

Grant Title: Ocular Surface Injury: Inflammatory Cascade and Healing of Corneal Wounds – 5R01-EY018239-10
Funding Agency: National Institutes of Health (NIH)
Role: Principal Investigator

Konstantin Tsoyi, Ph.D.

Grant Title: Antifibrotic Effects of Syndecan-2 and CD148 in Rheumatoid Arthritis Interstitial Lung Disease – AR074558 
Funding Agency: National Institutes of Health (NIH)
Role: Principal Investigator