The Center for Precision Medicine Models at Baylor College of Medicine aids researchers, clinicians, genetic counselors, patients and support organizations in the development and study of precision animal models of human-disease-associated genetic variation.
About the Center
The Baylor CPMM brings together internationally recognized leaders in clinical genetics, bioinformatics, and model organism research. Our goal is to develop precision animal models that will end the diagnostic odyssey of patients with undiagnosed genetic diseases and serve as resources for exploring personalized approaches to their care.
Our center focuses on producing and phenotyping precision fly and mouse models of human disease and can facilitate the discovery of spontaneous disease models in established rhesus macaque colonies. Visit cores for more details on the center’s capabilities.
Submit a Variant for Modeling
A clinician, genetic counselor, or researcher wishing to submit a variant for precision modeling can complete our Variant Submission Form.
Patients, families, or family organizations wishing to discuss the submission of a variant can contact the center at CPMM-info@bcm.edu.
Variant Submission Guidance
View our Variant Submission Guidance for more details on the criteria and variant submission and review processes. If a variant is selected for modeling, the center works closely with the submitter to develop an experimental plan that addresses key clinically relevant questions.
Track your Submission
Submitters are provided password protected access to our Submission Tracking System where their submitted information, status of the Center’s review, review comments, and a final decision letter can be accessed. When a project is accepted for animal modeling, the Submission Tracking System provides a link to our Project Management System where project progress can be monitored.
Available Animal Resources
All mouse and fly models produced by our center are available to the scientific community. Animal resources are either provided directly from the center or through publicly accessible repositories.
Funding Information
The Center for Precision Medicine Models at Baylor College of Medicine (U54 OD030165) is funded by the NIH Office of Research Infrastructure Programs through the Office of the Director. Efforts at Baylor are complemented by funded centers at The Jackson Laboratory and University of Alabama Birmingham.
Our Cores
Our center focuses on producing and phenotyping precision fly and mouse models of human disease and can facilitate the discovery of spontaneous disease models in established rhesus macaque colonies. Find out more about our center's core capabilities.
Baylor receives NIH funding for center to model rare genetic diseases
Baylor College of Medicine has received a five-year, $9.94 million grant from the National Institutes of Health for the new Center for Precision Medicine Models.