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The Equalizer: An engineered circuit for uniform gene expression
news › the-equalizer-an-engineered-circuit-for-uniform-gene-expression
… Equalizers. The findings, in the current edition of Nature Communications , show how researchers engineered these … protein expression. This property is called “gene dosage compensation.” The researchers use an analogy of heating a … negative feedback and post-transcriptional incoherent feedforward loops.  These loops counteract the presence of extra …
Texas Developmental Center for AIDS Research (Texas D-CFAR)
research › research-centers › texas-developmental-center-for-aids-research
… Texas Developmental Center for AIDS Research (Texas D-CFAR) focuses its research on the … in Texas— and helping others to do the same— in an effort to make high-impact contributions in the battle against … of top HIV researchers and clinicians Engages our community to implement solutions that optimize HIV health …
Dr. Vivi Chen Awarded NIH Grant for Outcomes Study
news › dr-vivi-chen-awarded-nih-grant-for-outcomes-study
… Dr. Vivi Chen … from potentially preventable morbidity and mortality.  Dr. Chen’s faculty mentors include Dr. Nader Massarweh and Dr. Laura Petersen. Dr. Chen is currently a second-year … Dr. Vivi Chen Awarded NIH Grant for Outcomes Study …
HeartCare study IDs patients’ genetic risk for cardiovascular disease
news › heartcare-study-ids-patients-genetic-risk-for-cardiovascular-disease
… in cardiovascular disease, leading to better outcomes in patient care. Researchers at Baylor College of … a pilot study to determine if providing genetic testing for patients in cardiovascular clinics would benefit … we can prevent cardiovascular events and improve outcomes. Genetic testing may help us to identify not only who …
Study reveals new pathway, potential treatment for neurological disorders
news › study-reveals-pathway-neurological-disorders
… are not synthesized. Mutations in genes encoding NMD components have been identified in some individuals with … is unknown. Thus, there are no current treatment options for these conditions. Together with investigators in … UPF2 is deficient in these individuals. To investigate what compromised Upf2-dependent NMD, they removed Upf2 in the …
Chemical approach created to discover compounds for drug development
news › chemical-approach-created-to-discover-compounds-for-drug-development
… Baylor College of Medicine have devised a chemical approach for discovering new enzyme-binding compounds that could be developed into drugs for various … processes. To rapidly identify small-molecule lead compounds to target healthcare-associated proteases, the …
Dr. Scully Selected for Hecht-Levi Fellowship in Bioethics
news › scully-hecht-levi-scholarship
… generation of bioethics scholars, granting protected time for research and publication. Hecht-Levi Fellows have the … lung transplantation. The ethical challenges surrounding informed consent, medical decision making, novel therapies, … and guide decision making in an increasingly complex patient population. …
Moderate dose of novel form of stress promotes longevity
news › novel-form-of-stress-longevity
… A newly described form of stress called chromatin architectural defect, or … Huffington Center on Aging and member of the Dan L Duncan Comprehensive Cancer Center at Baylor. “One of the factors … along chromatin and the structure folds further into more complicated configurations. Everything involving DNA would …
New Alkek Center for Molecular Discovery consolidates 'omics' efforts
news › new-alkek-center-consolidates-omics-efforts
… The new Alkek Center for Molecular Discovery builds on and expands Baylor College … in one gene," said O'Malley. "The next targets are more complex with multiple gene inputs along with influences of … It will expand the ‘omics' here and could result in BCM becoming an elite national leader in this broad field," he …
How we remember could help AI be less forgetful
news › how-we-remember-could-help-ai-be-less-forgetful
… networks, found in artificial intelligence (AI), from forgetting what they have previously learned. The study, in the current edition of Nature Communications , has implications for both neuroscience and … lose the ability to solve the previously learned task completely. This phenomenon, known as “catastrophic …

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