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research › ... › human-genetics
… the genetic causes for human diseases were largely limited to the study of extreme phenotypes produced by Mendelian … on the case-control design based on clinical diagnoses; however, this approach is potentially limited by etiologic … on underlying amyloid pathology; and further, our genome scan implicates common variation in the amyloid precursor …
departments › ... › fellows-highlights
… is first author on an article, entitled "The use of tracheostomy to support critically ill children receiving orthotopic … for publication. " Implementation of a High-Flow Nasal Cannula Management Protocol in the Pediatric ICU " , was … and wrote an Op-Ed article for the Houston Chronicle on “How to keep your kids safe at the pool or the beach." … Kyle …
news › dna-fracturing-rewires-gene-control-in-cancer
… the mechanisms that mediate widespread DNA damage in the cancer genome is of great interest to cancer physicians and scientists because it may lead to … the genome is moved to another part of the genome, which shows up as a break point in the sequence. Therefore, when …
academic-centers › ... › biobanking
… The … Dan L Duncan Comprehensive Cancer Center … is an NCI-designated … comprehensive cancer center located in the heart of the Houston metropolitan area, which is comprised of a unique … samples vary depending on the type of sample procured and how the sample is processed. For example, within the HTAP …
research › faculty-labs › mary-k-estes-lab
… genomic basis of infectious diseases and in understanding how the intestine repairs following infection. The use of … vitro and form mature intestinal epithelium upon growth factor manipulation. In order to increase the complexity of … 2020 Sep 9:202010834. doi: 10.1073/pnas.2010834117. A genetically engineered rotavirus NSP2 phosphorylation mutant …
news › nci-cog-pediatric-match-study-shows-benefit-of-genetic-screening-in-refractory-tumors
… Cancer therapies targeting specific genetic mutations may offer benefits to patients for whom other standard chemotherapy treatments have not effectively treated their tumor. However, genetic screening of tumors is not routinely …
news › car-t-cell-therapy-targeting-her2-antigen-shows-promise-against-advanced-sarcoma-in-phase-i-trial
… Researchers at Texas Children’s Cancer Center and the Center for Cell and Gene Therapy at … College of Medicine, Texas Children’s Hospital and Houston Methodist published results of a phase I clinical trial … on the surface of sarcoma cells. The HEROS 2.0 trial showed that this therapeutic approach is safe and is …
research › faculty-labs › hsiao-tuan-chao-lab
… One emerging theme in the field is that disrupted inhibitory neuronal development and function is found in … non-coding RNAs ( MEF2C-AS1 ). Our goal is to decipher how genetic alterations perturb the balance of excitation … graduate students. Future leaders in STEM at the Duncan NRI. Kudos to Dr. Maimuna Paul and the many team members …
departments › ... › child-neurology-residency
… accredited program that provides exceptional opportunities to study neurological diseases of children from infancy … equipment including its own operating rooms, MRI unit, CT scanners, interventional radiology unit, EEG and EMG … lecture series and clinical conferences and to learn how to become effective teachers . … Baylor is ranked among …
research › ... › software
… Description: … CanProVar is designed to store and display single amino acid alterations including … analysis plays an important role in systems biology. However, network analysis algorithms are usually …
