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news › bacteria-help-discover-cancer-causing-protein
… The researchers genetically modified bacteria so they would fluoresce red when DNA … each of the 4,000 genes present in E coli individually and determined which ones made bacteria glow red. “We … the University of Texas at Austin. See a complete list of all the contributors and their affiliations and the …
news › trial-shows-promise-treating-neuroblastoma
… in children, and patients with high-risk disease are challenging to treat. In a promising development, researchers … form of immunotherapy to treat neuroblastoma using genetically engineered natural killer T cells (NKTs). The findings … “This trial marks the first time highly pure and genetically engineered NKTs are being evaluated in humans to define …
news › tgf-beta-protects-against-uterine-cancer
… , director of the Center for Drug Discovery , Stuart A. Wallace Chair, Robert L. Moody, Sr. Chair and professor of … at Princeton University and their colleagues genetically modified mice to lack ALK5, which mediates TGF-beta … and her colleagues. In this case, the researchers genetically modified mice to lack two other proteins, Smad2 and …
healthcare › specialties › allergy-and-immunology
… a unique, comprehensive treatment option for patients with Allergic and Immunologic conditions in a single location. We diagnose and manage the following Allergic and Immunologic conditions and provide the … examination, perform and analyze the results from the allergy skin testing and other laboratory tests to determine …
news › early-environmental-exposure-impacts-liver-epigenome
… Communications , show how early life chemical exposure actually reprograms the liver epigenome, aging it more rapidly. … or “operating system” of the genome. It is comprised of small chemical modifications to DNA and the proteins that make up our chromosomes, and controls the activity of all the genes within the genome. During early life, as our …
news › car-t-cell-therapy-shows-promising-results-against-hodgkin-lymphoma
… treated at the highest dose level of therapy, with almost all patients having clinical benefit after treatment,” said … developed by Dr. Savoldo when she was at Baylor and initially translated to the clinic with Dr. Ramos, has now been … included flu-like symptoms due to an immune chemical storm called cytokine release syndrome, but these events were …
news › proteomics-analysis-ids-potential-drug-targets-for-aggressive-cancers
… of Medicine show that analysis of the proteomics, or all the protein data, from aggressive human cancers is a … to identify drivers of aggressive disease that could potentially be manipulated to control cancer growth. “That’s … cells. Cell migration is a property of cancer cells that allows them to spread cancer to other tissues. This work …
news › mouse-model-closely-reproduces-human-fatty-liver-disease
… the disease. “Our goal was to have a mouse model that would allow us to study the disorder and test potential … regarding genes that are regulated after the high-fat diet. All the analyses pointed at cholesterol metabolism being …
academic-centers › ... › our-partners
… cancer prevention and control services for the medically underserved residents of Harris County. Over the years, additional support from CPRIT has allowed us to expand our efforts to include breast cancer … and Hematology Centers, Texas Southern University, and Fallbrook Church Cancer Ministry. In 2023, we established the …
news › can-regulating-a-novel-brain-circuit-help-control-obesity
… that connects a unique group of dopamine-producing neurons called DA-VTA with downstream target neurons known as … the animals stopped eating. When the researchers genetically inhibited these neurons, the animals prolonged their feeding, drastically increasing the portion size. This suggests that …