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Celebrating a decade of neurological research at the Jan and Dan Duncan NRI
news › celebrating-a-decade-of-neurological-research-at-the-jan-and-dan-duncan-nri
… Last month, the Jan and Dan Duncan Neurological Research … world-renowned research and scientific breakthroughs.   On Dec. 8, 2010, the Duncan NRI opened and was the first … journals, discovered 72 disease-causing genetic mutations, completed one successful clinical trial for an intractable …
Novel brain circuit discovery and therapy might tackle coinciding obesity and depression
news › novel-brain-circuit-discovery-and-therapy-might-tackle-coinciding-obesity-and-depression
… Research has found that obesity and mental disorders such as depression and anxiety seem to often go hand in hand. Researchers at Baylor College of Medicine and collaborating institutions are providing new insights into this … provide evidence that supports the involvement of a neural component.” To investigate the neuronal circuits that could …
Technology Development for non-invasive prenatal genetic diagnosis using maternal peripheral blood (H-24326)
healthcare › clinical-trials › h-24326
… Study Goal(s): Development and validation of new methods to diagnose genetic … the fetus by studying cells and fetal DNA in the mother's blood. Eligibility Criteria: Pregnant women over 18 years old … or chorionic villus sampling Investigators: Ignatia Van den Veyver, M.D. (principal investigator) Supported by: …
Norovirus strains differ in sensitivity to the body’s first line of defense
news › norovirus-strains-differ-in-sensitivity-to-the-bodys-first-line-of-defense
… Interferon (IFN) responses are one of the first defenses the body mounts against viral infections, and research has shown that it plays a role controlling viral replication. But when … growth of HuNoV strain GII.3, but not of GII.4, the most common strain worldwide. The findings, published in the …
COVID-19 patients have increased oxidative stress, oxidant damage, and glutathione deficiency
news › covid-19-patients-have-increased-oxidative-stress-oxidant-damage-and-glutathione-deficiency
… glutathione, the most abundant physiological antioxidant. Compared to healthy age-matched individuals whose samples were taken before the pandemic started in 2019, patients hospitalized with COVID-19 … glutathione as well as improve health indicators such as inflammation, might be beneficial to COVID-19 …
Baylor College of Medicine names new dean of School of Health Professions
news › baylor-college-of-medicine-names-new-dean-of-school-of-health-professions
… Dr. Todd A. Reinhart has been named dean of the School of Health Professions at Baylor College … previously served as interim dean at Minnesota State Community and Technical College, where he oversaw 15 … of the Sciences. In this role he led the development and launch of multiple programs, including a Bachelor of Science …
AI used to reduce intrapartum stillbirths and early neonatal deaths in Malawi
news › ai-used-to-reduce-intrapartum-stillbirths-and-early-neonatal-deaths-in-malawi
… have a longstanding maternal neonatal health project in Malawi, in partnership with Baylor’s Children’s Foundation … professionals in the United States to promote safe outcomes for mothers and babies. The deployment of this … women, families and society that comes along with these preventable deaths.” Other contributors to this work include …
Researchers show benefit of ultra-deep RNA sequencing in Mendelian disorder diagnostics
news › researchers-show-benefit-of-ultra-deep-rna-sequencing-in-mendelian-disorder-diagnostics
… depths (about 50-150 million reads) that may not detect low-abundance transcripts and rare splicing events that are … platform, we substantially increased the detection of lowly expressed genes and transcripts,” said corresponding …  “With ultra-deep sequencing, we can evaluate many more low-expression genes that would be missed when sequenced at …
New center provides resources to develop and test new genome editing technologies
news › new-center-provides-resources-to-develop-and-test-new-genome-editing-technologies
… with somatic cell genome editing experiments in mouse models. Somatic cell genome editing, the ability to edit DNA … treatment for the most severe human diseases. Over the last decade, significant effort has gone into developing … to have this opportunity to serve the broader scientific community interested in somatic genome editing. Our goal is …
Understanding the brain mechanisms behind emotion processing bias in treatment-resistant depression
news › understanding-the-brain-mechanisms-behind-emotion-processing-bias-in-treatment-resistant-depression
… electroencephalography signals (sEEG) in the amygdala and prefrontal cortex (PFC) of the brain from treatment-resistant depression … Bottom-up processing is when sensory data or information comes into the brain, leading to a meaningful … Understanding the brain mechanisms behind emotion processing …

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