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news › novel-approach-prevents-liver-damage-in-animal-models-of-alagille-syndrome
… cases. The mutations affect multiple organs including the liver where it often results in cholestasis, a condition in which the flow of bile from the liver stops or slows, leading to bile buildup that in time … models were developed by manipulating a second gene in the livers of the first model, which resulted in severe to very …
healthcare › ... › amyotrophic-lateral-sclerosis
… and support for cognitive and emotional well-being. Care from a palliative care physician to assist with managing … cells in the brain and the spinal cord. Motor neurons reach from the brain to the spinal cord and from the spinal cord to the muscles throughout the body. The …
research › ... › can-we-regenerate-sensory-cells-of-the-inner-ear
… States, with approximately half of all adults suffering from some degree of hearing loss by the time they reach … has also been a huge problem in combat veterans returning from Iraq and Afghanistan. The most common form of hearing … non-mammalian vertebrates can functionally recover from deafening injury by mobilizing supporting cells in the …
research › faculty-labs › david-bates-lab
… From left: Mohan Joshi, David Magnan, Nick Stepankiw, Mark … by a 300-400 kb sliding window of sister chromatid cohesion from origin to terminus. We later showed that cohesion could … this tension affects fork progression, which likely ranges from fork slowing to complete fork arrest, and what …
news › dna-fracturing-rewires-gene-control-in-cancer
… in human cancers. The researchers brought together data from whole genome sequencing, gene expression and DNA methylation from more than 1,400 human cancers. They report today in the … sequencing a DNA segment, one may find two pieces of DNA from other regions fused together, which disrupts the …
departments › ... › michael-e-debakey-high-school-for-health-professions
… in honor of the famous physician. DHSHP has grown from 45 students attending classes at Baylor to a current … years. DHSHP also received awards for academic excellence from the Office of the Mayor of Houston (1994, 1995), HISD … scholarship offers. To date, 6,163 students have graduated from the school, and more than 99 percent of these students …
news › proteomics-analysis-ids-potential-drug-targets-for-aggressive-cancers
… that analysis of the proteomics, or all the protein data, from aggressive human cancers is a useful approach to … protein data that included tens of thousands of proteins from about 800 tumors including seven different cancer types … enables researchers to extract a new layer of information from these cancers,” Creighton said. “In this study, we …
news › baylor-college-of-medicine-names-new-endowed-chairs
… Hope Award in 2015, the Sue Eccles Young Investigator Award from the Metastasis Research Society in 2018 and Stand Up To … of Health funding and publication. He came to Baylor from Boston University where he served as section chief of … underserved populations in the Houston area benefit from innovative outreach, education, screening and primary …
academic-centers › ... › services
… such as GEO, Metabolomics Workbench. The core will collect from investigators sample metadata, fill in XML-format … improves availability by allowing for more rapid recovery from a disaster such as a fire or flood that incapacitates … 10s-100s of TB can be readily leased at very low cost from BCM Information Technology. Four cluster nodes are set …
news › protein-akap8-suppresses-breast-cancer-metastasis
… splicing, cells can make a large number of proteins from a limited number of genes. It would be like putting … as alternative splicing modulators that prevented cells from becoming metastatic. They identified a set of proteins … breast cancer animal model systems of cancer cells from human patients,” Cheng said. “We found that depletion …