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news › new-proteins-involved-in-spinocerebellar-ataxia-provide-insight-into-selective-neuronal-vulnerability
… Alzheimer’s and Parkinson’s disease result from the loss of specific types of neurons due to abnormal accumulation of … a mutant ATXN1 protein having long uninterrupted stretches called polyglutamine (polyQ) repeats. In healthy neurons, … models result from the enhanced activity of the ATXN1-CIC complex. However, ATXN1 protein is widely expressed and …
news › circadian-clock-gene-rev-erb-linked-to-dawn-phenomenon-in-type-2-diabetes
… Researchers at Baylor College of Medicine, Shandong University in China and other … journal Nature that mice lacking the circadian clock gene called Rev-erb in the brain show characteristics similar to … at Rev-erb gene expression in patients with type 2 diabetes comparing a group with dawn phenomenon to a group without it …
news › unraveling-the-complexity-of-vitamin-b12-diseases
… A team of researchers at Baylor College of Medicine and … B12 conditions that affect the same gene but are clinically distinct from the most common genetic vitamin B12 … of RONIN and HCFC1 proteins is a hybrid syndrome as it is both a cobalamin disorder and a disease of ribosomes, or a …
news › mapk4-novel-therapeutic-target-for-triple-negative-breast-cancer
… Scientific evidence supporting the involvement of the enzyme MAPK4 in cancer growth and resistance to … quickly. In a current study published in the journal Nature Communications , a team at Baylor College of Medicine and … by activating in cells a cancer-promoting signaling pathway called AKT,” Yang said. “Here we showed that this is also …
news › holiday-ingredient-substitutions
… The holidays often involve overindulging, and while the occasional … for those who want them, though.” Dessert Desserts that call for a lot of butter, solid fat or even coconut oil can … with other decadent foods compared to something like a bottle of wine. Wine and beer contain sugar, so they …
research › ... › lab-members
… My research focuses on the prevention of youth obesity and related diseases, such as … type 2 diabetes, and certain cancers, through the promotion of healthy diet and physical activity. Specifically, my work can be placed into one of three categories – … with Dr. Debbe Thompson’s research team in the Department of Pediatrics-Nutrition at Baylor College of Medicine …
news › unanticipated-aspects-of-the-genetic-regulation-of-different-brain-tumors-uncovered
… A team led by researchers at Baylor College of Medicine has shed new light on the genetic regulation of … chemical modifications to the DNA or associated proteins called epigenetic markers that determine which genes are … and ependymoma (EPN).” “We knew that Sox9 is elevated in both HGG and EPN. Also, we knew that these tumors have …
news › kipa-potentially-predicts-chemotherapy-response-in-triple-negative-breast-cancer
… Researchers at Baylor College of Medicine and collaborating institutions are developing a … R&D at AstraZeneca. The researchers used a laboratory assay called Kinase Inhibitor Pulldown Assay, or KIPA, to search … They searched for these proteins in 43 frozen tumor biopsies that were part of the previous Clinical Proteomic …
healthcare › ... › birth-injuries
… Injuries related to childbirth are common and can have a significant impact on a new mother. … the anus), within the vagina, near the urethra (where urine comes out), or on the labia. Perineal tears are also called vaginal tears or perineal lacerations. … There are four types of perineal tears. First- and second-degree tears are tears …
news › using-ai-to-improve-diagnosis-of-rare-genetic-disorders
… experienced geneticists. Investigators at Baylor College of Medicine are trying to make the process more efficient … intelligence. The team developed a machine learning system called AI-MARRVEL (AIM) to help prioritize potentially … gene candidates causing the rare disease. Researchers compared AIM’s results to other algorithms used in recent …
