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healthcare › clinical-trials › h-48387
… study in Parkinson's disease patients with dyskinesia to assess the efficacy and safety/tolerability of fixed dose combinations of JM-010 and its individual components. … The purpose of this study, which involved research, is to determine if investigational treatment, JM-010, is safe …
healthcare › clinical-trials › h-41067
… of a drug called RO7043015. RO7046015 is being developed for the possible treatment of Parkinson's disease. … antibodies are antibodies which have been engineered to recognize and bind to a specific type of protein. RO7046015 binds to a protein … PASADENA: A Study to Evaluate Intravenous RO7046015 (PRX002) in Participants …
healthcare › clinical-trials › h-49062
… multicenter, randomized, controlled pivotal trial to evaluate the safety and effectiveness of transcatheter … with the Edwards Pascal Transcatheter valve repair system compared to abbott mitraclip in patients with mitral regurgitation. … A study to evaluate transcatheter mitral valve repair with the …
news › trish-to-study-spaceflight-effects-on-genome-and-nervous-system-on-axiom-spaces-ax-3-mission
… The Translational Research Institute for Space Health (TRISH) will conduct a suite of human … and performance research projects during Axiom Space’s upcoming Axiom Mission 3 (Ax-3) to the International Space Station (ISS), scheduled to … TRISH to study spaceflight effects on genome and nervous system on …
news › dr-maria-elena-bottazzi-dr-teresa-a-davis-elected-to-the-national-academy-of-medicine
… Tropical Medicine at Baylor College of Medicine and co-director of the Texas Children's Hospital Center for Vaccine Development , and Dr. Teresa A. Davis , … have demonstrated outstanding professional achievement and commitment to service. “Drs. Bottazzi and Davis are leaders …
healthcare › clinical-trials › h-55239
… Double-Blind, Randomized Placebo-Controlled Study to Evaluate Efficacy and Safety and the Maintenance of Effect of 20-mg Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Patients with Major … The purpose of this study is to evaluate the safety, efficacy, and maintenance of effect …
healthcare › clinical-trials › h-53299
… is a next-generation small molecule cardiac myosin inhibitor being developed as a chronic, oral treatment for participants with hypertrophic cardiomyopathy (HCM). … and addressing the fundamental cause of this sarcomeric disease. This is the second Phase 3 trial of …
healthcare › clinical-trials › h-54042
… normal daily activities. SAGE-718 is a unique modulator (regulator of activity) of N-methyl-D-aspartate (NMDA) receptors. NMDA receptors are a type of protein with an important … A study of long-term safety and tolerability of Sage-718 in participants with Huntington's …
healthcare › clinical-trials › h-54088
… and safety of suvecaltamide in the treatment of moderate to severe residual tremor in participants with Parkinson's … The purpose of this study is to evaluate suvecaltamide in Parkinson’s disease … the Food and Drug Administration (FDA) has not approved it for the treatment of Parkinson’s disease or any other …
research › ... › research-projects
… heterogeneous in population and have multipotent capacity to differentiate into bone, adipocyte, cartilage and marrow … they continuously supply chondrocytes and osteoblasts for cartilage and bone formation, respectively, during … previously identified functionally distinct P-SSCs using a combination of Mx1 and SMA to selectively label resident …