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research › faculty-labs › perumal-thiagarajan-lab
… of the hypercoagulable state associated with the presence of antiphospholipid antibodies. Patients with systemic … The immunological specificity of these antibodies is complex and it ranges from phospholipid binding proteins, a … hypercoagulable state. We are also exploring the cause and consequences of anionic phospholipid exposure in blood …
research › faculty-labs › robia-pautler-lab
… The Pautler Lab develops and applies methodologies that permit … Manganese Enhanced MRI (MEMRI) Neuronal Tract Tracing … Her current research efforts build upon the new technique that she … is also paramagnetic, rendering it MRI detectable in spin-lattice (T1)-weighted MRI images. It is therefore possible …
research › faculty-labs › edward-cooper-lab
… The Cooper Lab is focused … on understanding and developing new treatments for forms of epilepsy affecting infants, children, and adults, mood disorder that often accompanies epilepsy, and related brain disease. These are … potassium and sodium ion channels that generate and conduct the action potential’s electrical currents. However, …
research › faculty-labs › frank-horrigan-lab
… Our research focuses on mechanisms that govern the opening and closing (gating) of ion channels. Ion channels are … Thus an understanding of ion channel gating has broad consequences for understanding normal cell function, disease … However, the mechanisms by which sensors and gates communicate represent a key aspect of channel gating that …
research › faculty-labs › monica-pillon-lab
… The Pillon Lab aims to uncover the structure, function, and regulation … with human disease. To define the molecular basis for gene dysregulation in disease states, we combine hybrid structural biology, enzymology, molecular … Pillon Lab … Baylor College of Medicine Department of Biochemistry & Molecular Biology One Baylor Plaza, …
research › faculty-labs › akash-patel-lab
… Our research lab focuses on determining the molecular underpinnings of inherited and sporadic forms of various … The most common primary intracranial tumors, meningiomas, also happen … One of the greatest scientific achievements of our time has been the sequencing of …
research › faculty-labs › lilei-zhang-lab
… theme of our research is to translate the study of genetic and epigenetic regulation of cardiovascular disease … novel therapeutic approaches. One area of our research combines molecular biology, cell biology and animal models … model. We use patient cells and their isogenic controls and a battery of phenotyping tools to understand …
research › faculty-labs › ming-zhou-lab
… that defines the boundary of a cell and of specialized compartments within a cell. Membrane proteins are embedded in lipid … and how substrates are translocated across the membrane or converted to a product. Since many of the membrane proteins … About the Lab … Ming Zhou Lab …
research › faculty-labs › paul-klotman-laboratory
… The Paul Klotman laboratory studies HIV-associated nephropathy (HIVAN) and … to HIV infection. HIVAN only afflicts people of African descent, and remains a leading cause of renal disease in the African American community. Additionally, as highly active anti-retroviral …
research › faculty-labs › thomas-westbrook-lab
… The central mission of the Westbrook lab is to develop genetic technologies to uncover vulnerabilities of cancer, … About the Lab … Thomas Westbrook Lab …