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news › disease-causing-genetic-changes-chromosome-17
… occurred because of the imbalance in the genetic information contained in the altered piece of chromosome 17, but a multidisciplinary team led by researchers at Baylor College of Medicine … two groups. One group includes individuals that have in common the same alterations in the same area of DNA. We call …
news › a-promising-approach-to-develop-a-birth-control-pill-for-men
… from 8 billion in 2022. These numbers underscore the need for considering family planning; however, there have been … Chemistry Technology (DEC-Tec) to screen our multi-billion compound collection to discover potent STK33 inhibitors,” … potent and selective. “Among these modified versions, compound CDD-2807 turned out to be the most effective,” Ku …
news › fda-ind-clearance-for-stxbp1-developmental-and-epileptic-encephalopathy-therapy
… clinical trial to study an investigational therapy for the treatment of a devastating childhood epilepsy … that CAP-002 may have potential to meaningfully improve outcomes in patients with this disease.” Gene therapy for … please reach out to Dr. Hsiao-Tuan Chao and her research team at chao-lab@bcm.edu. …
departments › ... › healthcare
… the surgical needs of the tens of thousands of patients visiting our affiliated hospitals each year from the Houston … follow-up of their care at all of our clinical sites. For General Surgery, call 713-798-7911 or visit our healthcare site . For the Hernia Center call …
news › novel-gene-variants-that-modify-risk-of-late-onset-alzheimers-disease-discovered
… Late-onset Alzheimer’s disease (LOAD) is the most common form of dementia in the elderly, affecting almost 44 … to these rules. Some people with APOEɛ4 remain disease-free while some APOEɛ2 carriers develop the disease. Using a … fruit fly screening developed by Juan and his team at the NRI. This is a good example of the power of …
news › huda-zoghbi-awarded-gruber-neuroscience-prize
… Prize of The Peter and Patricia Gruber Foundation for her pioneering work in unlocking the genetic and … lives of patients with neurological diseases, I am grateful for the foundation's support and for their ongoing efforts to promote awareness of advances …
healthcare › clinical-trials › h-40255
… Development of Adaptive Deep Brain Stimulation for Treatment-Resistant Obsessive Compulsive Disorder (OCD) The purpose of this study is to … could be up to 18 months and involves: A screening visit A baseline visit An inpatient surgery and … Deep Brain Stimulation for OCD …
research › ... › projects
… Developmental, translational and clinical studies for skeletal disorders and inborn errors of metabolism As a … disorders (specifically urea cycle disorders) as models of complex disease (those involving nitric oxide … pathogenesis of heritable disorders of connective tissue. Ultimately, I have attempted to translate these findings by …
research › ... › fgf-receptors-as-key-survival-factors-in-prostate-cancer
… gene. The dominant negative FGFR construct inhibited colony formation after hygromycin selection by over 99 percent in all three cell lines compared to vector controls. To determine the mechanism of … prostate cancer cells to traverse the G2/M checkpoint and ultimately for cell survival. We are seeking to understand …
research › faculty-labs › rachel-rau-lab
… with conventional chemotherapy in many cases, relapses are common and the therapy itself is highly toxic causing … that drive leukemogenesis and therapy resistance with the ultimate goal of translating these findings into better therapies for patients with leukemia. A major driver of leukemia …
