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news › sequencing-uncovers-cause-childhood-blindness
… for mutations in this gene in more patients, we found another four with this gene mutation. That confirmed our … that in humans, this is a partial loss of function. In other words, the protein's activity is compromised, causing … What we don't know is if it will have an effect later on in other organs. …
news › qa-ricin
… toxin, it is less toxic but it is much more toxic than many other proteins or protein toxins. … If untreated, a person can succumb or die from ricin intoxication in about three to five … likely) that it can be transferred from one person to another. If you are experiencing symptoms of exposure to …
news › insights-into-heart-healing-capacity
… fellow in the Martin lab during this project. “This and other evidence indicated that the Hippo pathway is required … signaling molecules that ‘talk’ to macrophages and other immune cells luring them into the heart,” Martin said. … for maintaining the fibroblasts in their resting state. Other contributors to this work include co-first author …
news › maternal-deaths-and-coronavirus
… a voluntary reporting of maternal cases with morbidity (occurrences of severe illness) or mortality (death) suspected … in pregnancy is the same, less, or greater than that of others. “We need to understand if COVID-19 is the exception … to quantify risk in pregnancy and explicitly discourage others from doing so,” Aagaard said. “The work of our team …
news › dawn-to-sunset-fasting-associated-with-anti-cancer-proteins
… proteins that are downregulated in several cancers and other disorders,” she said. Downregulation is the process … in blood pressure and sugar levels that could have occurred if breakfast was skipped or delayed to late morning … effects of these results are not yet known. There are also other questions about how often someone fasts or how diet …
news › fungi-cause-brain-infection-in-mice
… “An increasing number of clinical observations by us and other groups indicates that fungi are becoming a more common … upper airway allergic diseases such as asthma, as well as other conditions such as sepsis, a potentially … as the FIGGs formed, amyloid precursor proteins accumulated within the periphery and amyloid beta molecules …
news › factors-linked-poor-treatment-outcomes-all
… which children would not optimally respond to standard chemotherapy,” said first and corresponding author, Dr. Jeremy … to identify those patients and plan their treatment accordingly.” In this retrospective study, Schraw and his … time of diagnosis. At the end of their first block of chemotherapy, these patients were evaluated for minimal residual …
news › gut-bacteria-might-one-day-help-slow-down-aging
… of and also slow down the progression of tumors and the accumulation of amyloid-beta, a compound associated with … and molecular virology and microbiology at Baylor, and other colleagues who are experts in bacterial genetics. They … on some of the worm’s known processes linked to aging. Other mutants encouraged longevity by over-producing the …
news › postnatal-overnutrition-linked-to-aging
… pancreatic Islets of Langerhans, which produce insulin and other hormones. Islets of mice that were overnourished … islet malfunction and the onset of diabetes, but how they occur remains a mystery. Looking to shed light on this … of mice, one was overnourished during infancy and the other was not and represented the control group.“Adjusting …
news › the-equalizer-an-engineered-circuit-for-uniform-gene-expression
… feedforward loop can saturate because it requires other proteins that are present in limited quantities in the … with each circuit helping mitigate the limitation of the other. “The process we used for these findings was a … protein may mislocalize, aggregate, produce cytotoxicity or otherwise produce responses that are not physiological. It …
