2026
Chaudhury, A., Kongchan, N., … Zhao, N., … Ferreon, J., & Neilson, J. R. (2026). CELF1 is a non-canonical eIF4E binding protein that promotes translation of epithelial-mesenchymal transition effector mRNAs. Nucleic Acids Research, 54(5). https://doi.org/10.1093/nar/gkag123
Pedroza, D. A., Yuan, X., … Zhao, N., … Zhang, X., & Rosen, J. M. (2026). Anti-CSF-1R therapy with combined immuno-chemotherapy coordinate an adaptive immune response to eliminate macrophage enriched triple negative breast cancers. Nature Communications, 17(1), 1193. https://doi.org/10.1038/s41467-025-67964-2
2025
Zhao, N. (2025). My academic job offer was rescinded. I'll keep going—but U.S. researchers are running out of road. Science (Working Life).
2024
Xu, L., Peng, F., … Zhao, N., … Rosen, J. R., & Chen, X. (2024). IRE1α silences dsRNA to prevent taxane-induced pyroptosis in triple-negative breast cancer. Cell, 187(25), 7248–7266. https://doi.org/10.1016/j.cell.2024.09.032
Yuan, X., Hao, X., Chan, H. L., Zhao, N., … Zhang, X., & Rosen, J. M. (2024). CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer. JCI Insight, 9(20), e182621. https://doi.org/10.1172/jci.insight.182621
2023
Zhao, N., Kabotyanski, E., Saltzman, A., … Perou, C., & Rosen, J. M. (2023). Targeting EIF4A triggers an interferon response to synergize with chemotherapy and suppress triple-negative breast cancer. Journal of Clinical Investigation, 133(24). https://doi.org/10.1172/JCI172503
2022
Zhao, N., & Rosen, J. M. (2022). Breast cancer heterogeneity through the lens of single-cell analysis and spatial pathologies. Seminars in Cancer Biology, 82, 3–10. https://doi.org/10.1016/j.semcancer.2021.07.010
Si, H., Zhao, N., Pedroza, A., Zaske, A. M., Rosen, J. M., Creighton, C. J., & Roarty, K. (2022). Noncanonical Wnt/Ror2 signaling regulates cell–matrix adhesion to prompt directional tumor cell invasion in breast cancer. Molecular Biology of the Cell, 33(11), ar103. https://doi.org/10.1091/mbc.E22-02-0055
Singh, S., Lee, N., … Zhao, N., … Perou, C. M., Zhang, X., & Rosen, J. M. (2022). Chemotherapy coupled to macrophage inhibition induces T-cell and B-cell infiltration and durable regression in triple-negative breast cancer. Cancer Research, 82(12), 2281–2297. https://doi.org/10.1158/0008-5472.CAN-21-3714
Xiao, M. H., Lin, Y. F., … Zhao, N., … Zhu, Y., & Fang, J. H. (2022). Downregulation of a mitochondrial micropeptide, MPM, promotes hepatoma metastasis by enhancing mitochondrial complex I activity. Molecular Therapy, 30(2), 714–725. https://doi.org/10.1016/j.ymthe.2021.08.032
2021
Zhao, N., Powell, R. T., … Stephan, C. C., & Rosen, J. M. (2021). Morphological screening of mesenchymal mammary tumor organoids to identify drugs that reverse epithelial-mesenchymal transition. Nature Communications, 12(1), 4262. https://doi.org/10.1038/s41467-021-24545-3
Janghorban, M., Yang, Y., Zhao, N., Hamor, C., Nguyen, T. M., Zhang, X. H., & Rosen, J. M. (2021). Single cell analysis unveils the role of the tumor immune microenvironment and Notch signaling in dormant minimal residual disease. Cancer Research, 82(5), 885–899. https://doi.org/10.1158/0008-5472.CAN-21-1230
2020
Xie, C., Zhang, L. Z., … Zhao, N., He, X., & Zhuang, S. M. (2020). A hMTR4-PDIA3P1-miR-125/124-TRAF6 regulatory axis and its function in NF-κB signaling and chemoresistance. Hepatology, 71(5), 1660–1677. https://doi.org/10.1002/hep.30931
Nguyen, T. M., Kabotyanski, E. B., … Zhao, N., … Li, W., & Rosen, J. M. (2020). The SINEB1 element in the long non-coding RNA Malat1 is necessary for TDP-43 proteostasis. Nucleic Acids Research, 48(5), 2621–2642. https://doi.org/10.1093/nar/gkz1176
2019
Guo, Z. W., Meng, Y., Xie, C., Zhao, N., … & Wu, Y. S. (2019). Translated long non-coding ribonucleic acid ZFAS1 promotes cancer cell migration by elevating reactive oxygen species production in hepatocellular carcinoma. Frontiers in Genetics, 10, 1111. https://doi.org/10.3389/fgene.2019.01111
Wang, X., Wang, B., Zhao, N., … Huang, S., & Liu, Y. (2019). Pharmacological targeting of BET bromodomains inhibits lens fibrosis via downregulation of MYC expression. Investigative Ophthalmology & Visual Science, 60(14), 4748–4758. https://doi.org/10.1167/iovs.19-27596
Kim, I. S., Gao, Y., … Zhao, N., … Rosen, J. M., & Zhang, X. H. (2019). Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms. Nature Cell Biology, 21(9), 1113–1126. https://doi.org/10.1038/s41556-019-0373-7
Lin, Y. F., Xiao, M. H., … Zhao, N., … Zhu, Y., & Zhuang, S. M. (2019). A novel mitochondrial micropeptide MPM enhances mitochondrial respiratory activity and promotes myogenic differentiation. Cell Death & Disease, 10(7), 528. https://doi.org/10.1038/s41419-019-1767-y
Vijay, G. V., Zhao, N., … Rosen, J. M., & Mani, S. A. (2019). GSK3β regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer. Breast Cancer Research, 21(1), 1–14. https://doi.org/10.1186/s13058-019-1125-0
Zhao, N., Peng, F., & Chen, X. (2019). The unfolded protein response in triple-negative breast cancer. In The Unfolded Protein Response in Cancer (pp. 133–161). Humana Press.
2018
Zhao, N., Cao, J., … Lewis, M. T., & Chen, X. (2018). Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. Journal of Clinical Investigation, 128(4), 1283–1299. https://doi.org/10.1172/JCI95873
Lu, Y., Cao, J., Napoli, M., Xia, Z., Zhao, N., … McManus, M. T., & Rosen, J. M. (2018). miR-205 regulates basal cell identity and stem cell regenerative potential during mammary reconstitution. Stem Cells, 36(12), 1875–1889. https://doi.org/10.1002/stem.2914
Wang, R., Fu, T., You, K., Li, S., Zhao, N., Yang, J., & Zhuang, S. M. (2018). Identification of a TGF-β-miR-195 positive feedback loop in hepatocytes and its deregulation in hepatoma cells. FASEB Journal, 32(7), 3936–3945. https://pubmed.ncbi.nlm.nih.gov/29465312/
2016
Zhao, N., Li, S., Wang, R., Xiao, M., Meng, Y., Zeng, C., Fang, J. H., Yang, J., & Zhuang, S. M. (2016). Expression of microRNA-195 is transactivated by Sp1 but inhibited by histone deacetylase 3 in hepatocellular carcinoma cells. BBA-Gene Regulatory Mechanisms, 1859(7), 933–942. https://doi.org/10.1016/j.bbagrm.2016.05.006
2014
Zhao, N., Wang, R., Zhou, L., Zhu, Y., Gong, J., & Zhuang, S. M. (2014). MicroRNA-26b suppresses the NF-κB signaling and enhances the chemosensitivity of hepatocellular carcinoma cells by targeting TAK1 and TAB3. Molecular Cancer, 13(1), 1–11. https://doi.org/10.1186/1476-4598-13-35
2013
Wang, R., Zhao, N., Li, S., Fang, J. H., … & Zhuang, S. M. (2013). MicroRNA-195 suppresses angiogenesis and metastasis of hepatocellular carcinoma by inhibiting the expression of VEGF, VAV2, and CDC42. Hepatology, 58(2), 642–653. https://doi.org/10.1002/hep.26373