Mustafa Tosur Lab Publications

Relan S, Alarcon G, Guffey D, Minard CG, Fang ME, Timmons K, Sonabend RY, Tosur M, Redondo MJ, Posey JE. Maturity-Onset Diabetes of the Young (MODY) in a Racially/Ethnically Diverse Pediatric Population. J Clin Endocrinol Metab. 2025 Jun 24. Online ahead of print.

Tosur M, Onengut-Gumuscu S, Redondo MJ. Type 1 Diabetes Genetic Risk Scores: History, Application and Future Directions. Curr Diab Rep. 2025 Feb 8;25(1):22.

Jahoor F, Hsu JW, Keene KR, Peacock WF, Huang X, Guffey D, Byun J, Bennet R, Lernmark A, Tosur M, Balasubramanyam A. Amino acids and CART distinguish A-β+ Ketosis-Prone Diabetes from type 1 and type 2 diabetes during hyperglycemic crises. J Clin Endocrinol Metab. 2025 Jan 16.

McCullough ME, Letourneau-Freiberg LR, Naylor RN, Greeley SAW, Broome DT, Tosur M, Kreienkamp RJ, Cobry E, Rasouli N, Pollin TI, Udler MS, Billings LK, Desouza C, Evans-Molina C, Birz S, Furner B, Watkins M, Ott K, Volchenboum SL, Philipson LH. Advancing Monogenic Diabetes Research and Clinical Care by Creating a Data Commons: The Precision Diabetes Consortium (PREDICT). J Diabetes Sci Technol. 2025 Jan 9

Kreienkamp RJ, Shields BM, Pollin TI, Shah AS, Liese AD, Bellatorre A, Pihoker C, Tosur M, Florez JC, Srinivasan S, Hattersley AT, Udler MS, Redondo MJ. MODY Calculator and Clinical Features Routinely Used to Distinguish MODY From Type 2 Diabetes in Adults Perform Poorly for Youth Clinically Diagnosed With Type 2 Diabetes. Diabetes Care. 2025 Jan 1;48(1):e3-e5.

Tosur M. Maturity-onset diabetes of the young: A proposal for updated nomenclature. J Diabetes Investig. 2024 Dec;15(12):1818-1819.

Tosur M, Deen S, Huang X, Uysal S, Astudillo M, Oram RA, Redondo MJ, Jahoor F, Balasubramanyam A. Random C-Peptide and Islet Antibodies at Onset Predict β Cell Function Trajectory and Insulin Dependence in Pediatric Diabetes. Endocr Pract. 2024 Dec;30(12):1149-1157.

Bacha F, Hannon TS, Tosur M, Pike JM, Butler A, Tommerdahl KL, Zeitler PS. Pathophysiology and Treatment of Prediabetes and Type 2 Diabetes in Youth. Diabetes Care. 2024 Dec 1;47(12):2038-2049.

Haller MJ, Bell KJ, Besser REJ, Casteels K, Couper JJ, Craig ME, Elding Larsson H, Jacobsen L, Lange K, Oron T, Sims EK, Speake C, Tosur M, Ulivi F, Ziegler AG, Wherrett DK, Marcovecchio ML. ISPAD Clinical Practice Consensus Guidelines 2024: Screening, Staging, and Strategies to Preserve Beta Cell Function in Children and Adolescents with Type 1 Diabetes. Horm Res Paediatr. 2024 Dec 11:1-30. Online ahead of print.

Gupta EA, Huang X, Velasquez HJ, Golani K, Siller AF, Minard CG, Tosur M, Redondo MJ. Age and sex mark clinical differences in the presentation of pediatric type 1 diabetes mellitus. J Pediatr Endocrinol Metab. 2024 Nov 28. Online ahead of print.

Astudillo MF, Winter WE, Billings LK, Kreienkamp R, Balasubramanyam A, Redondo MJ, Tosur M; RADIANT Study Group. Identification of atypical pediatric diabetes mellitus cases using electronic medical records. BMJ Open Diabetes Res Care. 2024 Nov 7;12(6):e004471.

Alarcon G, Nguyen A, Jones A, Shields B, Redondo MJ, Tosur M. The Maturity-Onset Diabetes of the Young (MODY) Calculator Overestimates MODY Probability in Hispanic Youth. J Clin Endocrinol Metab. 2024 Nov 4:dgae770. Online ahead of print.

Alarcon G, Maston GA, Hoffman CA, Posey JE, Redondo MJ, Tosur M. Variants of Unknown Significance in Maturity-Onset Diabetes of the Young: High Rate of Conundrum Resolution via Variants of Unknown Significance Reanalysis. Horm Res Paediatr. 2024 May. Online ahead of print.

Triolo TM, Parikh HM, Tosur M, Ferrat L, You L, Gottlieb PA, Oram RA, Onengut-Gumuscu S, Krischer JP, Rich SS, Steck AK, Redondo MJ. Genetic Associations with C-peptide Levels before Type 1 Diabetes Diagnosis in At-Risk Relatives. J Clin Endocrinol Metab. 2024 May 20, Online ahead of print.

Tosur M, Huang X, Inglis AS, Aguirre RS, Redondo MJ. Inaccurate diagnosis of diabetes type in youth: prevalence, characteristics, and implications. Sci Rep. 2024 Apr 17;14(1):8876.

Kubota-Mishra E, Huang X, Minard CG, Astudillo M, Refaey A, Montes G, Sisley S, Ram N, Winter WE, Naylor RN, Balasubramanyam A, Redondo MJ, Tosur M, RADIANT Study Group, "High Prevalence of A−β+ Ketosis-Prone Diabetes in Children with Type 2 Diabetes and Diabetic Ketoacidosis at Diagnosis: Evidence from the Rare and Atypical Diabetes Network (RADIANT)", Pediatric Diabetes, 2024 Mar; vol. 2024, Article ID 5907924.

Redondo MJ, Harrall KK, Glueck DH, Tosur M, Uysal S, Muir A, Atkinson EG, Shapiro MR, Yu L, Winter WE, Weedon M, Brusko TM, Oram R, Vehik K, Hagopian W, Atkinson MA, Dabelea D; DISCOVER Study Group. Diabetes Study of Children of Diverse Ethnicity and Race: Study design. Diabetes Metabolism Research Review. 2024 Mar; 40(3):e3744.

Jacobsen LM, Sherr JL, Considine E, Chen A, Peeling SM, Hulsmans M, Charleer S, Urazbayeva M, Tosur M, Alamarie S, Redondo MJ, Hood KK, Gottlieb PA, Gillard P, Wong JJ, Hirsch IB, Pratley RE, Laffel LM, Mathieu C; ADA/EASD PMDI. Utility and precision evidence of technology in the treatment of type 1 diabetes: a systematic review. Commun Med (Lond). 2023 Oct 5;3(1):132.

Tosur M, Hsu JW, Deen S, Huang X, Guffey D, Uysal S, Astudillo M, Redondo MJ, Jahoor F and Balasubramanyam A. Plasma amino acid signatures define types of pediatric diabetes. Clinical Nutrition ESPEN, June 2023, Online ahead of print.

Abbasi M, Tosur M, Astudillo M, Refaey A, Sabhrawal A, Redondo MJ. Clinical Characterization of Data-driven Diabetes Clusters of Pediatric Type 2 Diabetes. Pediatric Diabetes. 2023:6955723. Epub 2023 Jul.

Ismail H, Baru S, Wang J, Sabharwal A, Libman I, Bacha F, Nadeau K, Tosur M, Redondo MJ. Predictors of Response to Metformin in Adolescents with Type 1 Diabetes and Increased BMI. Diabetes, Obesity and Metabolism, June 2023, Online ahead of print.

RADIANT Study Group (Balasubramanyam A, Redondo MJ, … Tosur M, … Marcovina SM, Newgard CB. The Rare and Atypical Diabetes Network (RADIANT) Study: Design and Early Results. Diabetes Care, 2023 Jun 1; 46(6):1265-1270.

Castillo Rodriguez B, Astudillo M, Tosur M, Rafaey A, McKay S, Bacha F, Balasubramanyam A, Redondo MJ. Characteristics of Type 2 Diabetes in Female and Male Youths. Clinical Diabetes. 2023 Spring; 41(2): 239-243.

Tosur M, Gandolfo L, Balasubramanyam A, Naylor RN, Pollin TI, Rasouli N, Cromer SJ, Buse JB, Redondo MJ, RADIANT Study Group. Enrollment of Underrepresented Racial and Ethnic Groups in the Rare and Atypical Diabetes Network (RADIANT). Journal of Clinical and Translational Science. 2023 Jan 23; 7(1):e47.

Miyake CY, Lay EJ, Soler-Alfonso C, Glinton KE, Houck K, Tosur M, Moran NE, Stephens SB, Scaglia F, Howard TS, Kim JJ, Pham TD, Valdes SO, Li N, Murali C, Zhang L, Kava M, Yim D, Beach C, Webster G, Liberman L, Janson C, Kannankeril PJ, Baxter S, Singer-Berk M, Wood J, Mackenzie S, Sacher M, Gonzalez L, Pedroza C, Morris SA, Ehsan SA, Azamian M, Lalani SR.Natural History of TANGO2 Deficiency Disorder: Baseline Assessment of 73 Patients. Genetics in Medicine. 2023 Apr; 25(4):100352.

Vakharia M, Pehlivan D, Martinez A, Glaze D, Tosur M. New-onset diabetes presenting with hyperosmolar hyperglycemic state in a lean adolescent with atypical Rett syndrome using antipsychotics. Clinical Diabetes. 2022, Fall; 40(4):503-507.

Tosur M, Phillipson LH. Precision Diabetes: Lessons Learned from Maturity-Onset Diabetes of the Young (MODY). J Diabetes Investig. 2022, Sep; 13(9)1465-1471.

Miyake CY, Lay EJ, Beach CM, Ceresnak SR, Delauz CM, Howard TS, Janson CM, Jardine K, Kannankeril PJ, Kava M, Kim JJ, Liberman L, Macicek SL, Pham TD, Robertson T, Valdes SO, Webster G, Stephens SB, Milewicz DM, Azamian M, Ehsan SA, Houck KM, Soler-Alfonso C, Glinton KE, Tosur M, Li N, Xu W, Lalani SR, Zhang L. Cardiac Crises: Cardiac Arrhythmias and Cardiomyopathy during TANGO2-deficiency related Metabolic Crises. Heart Rhythm. 2022, Oct; 19 (10): 1673-1681.

Menon S, Refaey A, Guffey D, Balasubramanyam A, Redondo MJ, Tosur M. Optimizing maturity-onset diabetes of the young detection in a pediatric diabetes population. Pediatric Diabetes. 2022, Jun; 23 (4): 447-456.

Kumar RD, Tosur M, Lalani SR, Mahoney DH Jr, Bertuch AA. The germline p53 activation syndrome: A new patient further refines the clinical phenotype. Am J Med Genet A. 2022, Jul; 188 (7): 2204-2208.

Tosur M, Soler-Alfonso C, Chan KM, Khayat MM, Jhangiani SN, Meng Q, Refeay A, Muzny D, Gibbs RA, Murdock DR, Posey J, Balasubramanyam A, Redondo MJ, Sabo A. Exome Sequencing in Children with Clinically Suspected Maturity-Onset Diabetes of the Young. Pediatric Diabetes. 2021 Nov; 22(7): 960-968.

Astudillo M, Tosur M, Castillo B, Rafaey A, Siller AF, Nieto J, Sisley S, McKay S, Nella AA, Balasubramanyam A, Bacha F, Redondo MJ. Type 2 Diabetes in Prepubertal Children. Pediatric Diabetes. 2021 Apr; 7 (6): 418-421.

Nieto J, Castillo B, Astudillo M, Tosur M, Balasubramanyam A, Pietropaolo M, Redondo MJ. Islet autoantibody types mark differential clinical characteristics at diagnosis of pediatric type 1 diabetes. Pediatric Diabetes. 2021 Sep; 22 (6): 882-888.

Tosur M, Geary CA, Matalon R, Radhakrishnan RS, Swischuk LE, Tarry WF, Dong J, Lee PD. Corrigendum Re: “Persistence of Müllerian Duct Structures in a Genetic Male with Distal Monosomy 10q. Am J Med Genet A. 2015 Apr;167A(4):791-6. Doi: 10.1002/ajmg.a.37014”. Am J Med Genet A. 2021 June, Doi:10.1002/ajmg.a.62358

Miyake CY, Kim JJ, Tosur M, Howard TS, Pham T, Valdes SO. Severe Hypoglycemia Associated with Oral Sotalol Use in Two Children. Heart Rhythm Case Reports. 2021, June; 7(6):418-421.

Redondo MJ, Siller AF, Gu X, Tosur M, Bondy M, Devaraj S and Sisley S. Sex differences in circulating leptin as a marker of adiposity in obese or overweight adolescents with type 1 diabetes. BMJ Open Diabetes Research and Care. 2020, Oct; 8(1):e001683.

Tosur M, Cleves M, Sosenko J, Libman I, Baidal D, Balasubramanyam A, Redondo MJ. The Effect of Ethnicity in the Rate of Beta Cell Functional Loss in the First 3 Years After Type 1 Diabetes Diagnosis. Journal of Clinical Endocrinology and Metabolism. 2020, Dec 1; 105(12):e4393-406.

Siller AF, Tosur M, Relan S, Astudillo M, McKay S, Dabelea D, Redondo MJ. Challenges in the Diagnosis of Diabetes Type in Pediatrics. Pediatric Diabetes. 2020 Nov; 21(7):1064-1073.

Tosur M*, Viau-Colindres J*, Astudillo M, Redondo MJ, Lyons SK. Medication-Induced Hyperglycemia: Pediatric Perspective. BMJ Open Diabetes Res Care. 2020, Jan; 8(1):e000801.

Redondo MJ, Sosenko J, Libman I, McVean JJF, Tosur M, Atkinson MA, Becker D, Geyer S. Single Islet Autoantibody at Diagnosis of Clinical Type 1 Diabetes is Associated with Older Age and Insulin Resistance. Journal of Clinical Endocrinology & Metabolism. 2020 May; 105(5):1629-40.

Tosur M, Rodriguez H, Libman I, Baidal D, Redondo MJ. Ethnic Differences in Progression to Type 1 Diabetes in Relatives at Risk. Diabetologia. 2018 Sep; 61(9):2043-2053.

 Tosur M, Redondo MJ, Lyons SK. Adjuvant pharmacotherapies to Insulin for the Treatment of Type 1 Diabetes. Curr Diab Rep. 2018 Aug; 18 (10):79.

Tosur M, Redondo MJ. Heterogeneity of Type 1 Diabetes: The Effect of Ethnicity. Current Diabetes Reviews. 2018; 14(3):266-272.

Redondo MJ, Libman I, Tosur M, Cheng P, Gal R, Klingensmith G, Clements M. Racial/Ethnic Minority Youth with Recent-Onset Type 1 Diabetes Have Poor Prognostic Factors. Diabetes Care. 2018 May;41(5):1017-1024.

Tosur M. Letter to the Editor: Autoimmune Diseases in Children and Adults with Type 1 Diabetes from the T1D Exchange Clinic Registry. Clin Pediatr (Phila). 2018 May; 57 (5):621.

Tosur M, Collins MT, Ponder SW, Stratakis CA, Karaviti LP and Jeha GS. Persistent Diabetes Mellitus Post-adrenalectomy in Neonatal McCune-Albright Syndrome. Global Pediatric Health. 2017 Nov; 4:2333794X17742748; eCollection.

Gandhi K, Tosur M, Schaub R, Haymond MW, Redondo MJ. Racial and Ethnic Differences among Youth with New Onset Autoimmune Type 1 Diabetes. Diabetic Medicine. 2017 Oct; 34(10):1435-1439.

Tosur M. Modified Nomogram for Derivation of Renal Threshold Phosphate Concentration. International Urology and Nephrology Journal. 2017 Jul; 49(7): 1309-1310.

Tosur M, Jeha GS. A Novel Intragenic SLC16A1 Mutation Associated with Congenital Hyperinsulinism. Global Pediatric Health. 2017 April; 4:2333794X17703462; eCollection.