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Ang Li Lab

Ang Li Lab Projects and Publications

Master
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Epidemiology and biomarkers in transplant associated thrombotic microangiopathy

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A Prospective Validation Cohort Study: The goals are to prospectively assess the incidence of TA-TMA in a large pediatric cohort and to test a dynamic risk prediction tool that incorporates validated clinical and laboratory biomarkers in immune, endothelial, and complement activation pathways.

Funding: NIH/NHLBI - K23HL159271, April 1, 2022 - March 31, 2027

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Epidemiology, health disparity, and risk stratification for cancer associated thrombosis

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The goal of this project is to study the epidemiology and prevention of cancer-associated thrombosis and to determine the patient and societal impact of a thromboprophylaxis program.

Funding: Cancer Prevention & Research Institute of Texas (CPRIT) RR190104,  Aug. 31, 2019 - Aug. 30, 2024

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Risk factors and burden of COVID-19 related thrombosis and bleeding complication:

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The goals are to determine the incidence of thrombosis and bleeding and to assess benefit/harm of therapeutic anticoagulation among hospitalized patients with COVID-19 across different hospital systems. There was a specific focus on people with cancer and thrombosis.

Funding: CDC - 6NU38OT000280-03-02, Sept. 1, 2020 - Jul 31, 2022

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Management of thrombosis and bleeding in hematopoietic cell transplant patients:

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The goals are to assess the incidence of and risk factors for thrombosis and bleeding in people undergoing hematopoietic cell transplantation. A novel risk prediction model was derived and externally validated.

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Rapid diagnosis of immune thrombotic thrombocytopenic purpura

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The goals are to characterize patients with high pre-test probability for iTTP. Specifically, a risk prediction model was derived and externally validated for iTTP.

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Comparative and cost effectiveness research in hematology

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The gaosl are to better understand the societal implications of novel treatment approaches in anticoagulation through systematic review, meta-analysis, and cost effectiveness analysis.