Wofford Cain Chair and Professor
Molecular and Human Genetics
Baylor College of Medicine
Human Genome Sequencing Center
Baylor College of Medicine
Program in Translational Biology & Molecular Medicine
Baylor College of Medicine
Program in Integrative Molecular and Biomedical Sciences
Baylor College of Medicine
Baylor College of Medicine
Houston, TX, US
Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas, United States


BS from University Of Melbourne
PhD from University Of Melbourne
Post-Doctoral Fellowship at Baylor College Of Medicine

Honors & Awards

Elected to the Institute of Medicine
LSU Chancellor's Distinguished Lectureship
Michael E. DeBakey, M.D., Excellence in Research Award
George R. Sampson Distinguished Research Fellowship
Postdoctoral Fellowship
Postdoctoral Fellowship
Wofford Cain Chair in Molecular and Human Genetics

Professional Interests

  • Genome science, human molecular evolution, and molecular basis of inherited disease

Professional Statement

Richard Gibbs is the Founder and Director of the Human Genome Sequencing Center (HGSC), established at BCM in 1996. The HGSC has a core mission of advancing medical care through research and translation of genomics. The group was one of the five worldwide sites to undertake and complete the Human Genome Project, culminating in contribution of approximately ten percent of the sequence in 2003. The group subsequently collaborated to sequence many key species (Drosophila melanogaster, the Brown Norway rat, rhesus macaque, bovine, Dictyostelium discoideum, sea urchin and honey bee genomes) and to generate the first comprehensive map of human genetic variation (the HapMap project). The HGSC now employs more than 180 staff, including eighteen faculty.

Since 2007, new technologies have allowed unprecedented advances in human genetics. The HGSC pioneered whole exome capture methods and published the first diploid sequence of a human, James Watson. Next we demonstrated the utility of whole genome sequencing for genetic disease discovery and for guiding effective clinical treatments. In 2011, we began deploying these methods into routine clinical practice and now provide full gene sequencing to hundreds of individual patients each month.

Current research within the HGSC is focused upon the genomics of cancer, heart disease and autism. To achieve this the group is sequencing single human genomes at an increasing rate. New molecular technologies are being developed for the mapping and sequencing, for exploring novel chemistries for DNA tagging, and to enable development of instrumentation for DNA manipulation. The HGSC is also part of the national program for systematic discovery of the cause of human single genome defects and has an active bioinformatics program, with research projects involving biologists and computer scientists. Problems under study focus on developing tools for generating, manipulating, and analyzing genome data.

Selected Publications